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This work proposes a deep learning (DL)-based framework, namely Sim2Real, for spectral signal reconstruction in reconstructive spectroscopy, focusing on efficient data sampling and fast inference time. The work focuses on the challenge of…

Machine Learning · Computer Science 2024-08-20 Jiyi Chen , Pengyu Li , Yutong Wang , Pei-Cheng Ku , Qing Qu

Deep Learning (DL) algorithms hold great promise for applications in the field of computational biophysics. In fact, the vast amount of available molecular structures, as well as their notable complexity, constitutes an ideal context in…

Soft Condensed Matter · Physics 2019-01-07 Marco Giulini , Raffaello Potestio

Dramatic advances in the quality of the latent diffusion models (LDMs) also led to the malicious use of AI-generated images. While current AI-generated image detection methods assume the availability of real/AI-generated images for…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Sungik Choi , Hankook Lee , Jaehoon Lee , Seunghyun Kim , Stanley Jungkyu Choi , Moontae Lee

Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique in biomedical research that uses the fluorophore decay rate to provide additional contrast in fluorescence microscopy. However, at present, the calculation, analysis,…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Varun Mannam , Yide Zhang , Xiaotong Yuan , Cara Ravasio , Scott S. Howard

Recently, deep learning-based compressive imaging (DCI) has surpassed the conventional compressive imaging in reconstruction quality and faster running time. While multi-scale has shown superior performance over single-scale, research in…

Image and Video Processing · Electrical Eng. & Systems 2020-08-04 Thuong Nguyen Canh , Byeungwoo Jeon

Advances in microscopy imaging enable researchers to visualize structures at the nanoscale level thereby unraveling intricate details of biological organization. However, challenges such as image noise, photobleaching of fluorophores, and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Pamela Osuna-Vargas , Maren H. Wehrheim , Lucas Zinz , Johanna Rahm , Ashwin Balakrishnan , Alexandra Kaminer , Mike Heilemann , Matthias Kaschube

Three-dimensional (3D) fluorescence microscopy in general requires axial scanning to capture images of a sample at different planes. Here we demonstrate that a deep convolutional neural network can be trained to virtually refocus a 2D…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Yichen Wu , Yair Rivenson , Hongda Wang , Yilin Luo , Eyal Ben-David , Laurent A. Bentolila , Christian Pritz , Aydogan Ozcan

To operate quantum sensors at their quantum limit in real time, it is crucial to identify efficient data inference tools for rapid parameter estimation. In photodetection, the key challenge is the fast interpretation of click-patterns that…

Quantum Physics · Physics 2026-02-24 Mateusz Molenda , Lewis A. Clark , Marcin Płodzień , Jan Kolodynski

We leverage deep learning techniques to jointly denoise and super-resolve biomedical images acquired with fluorescence microscopy. We develop a deep learning algorithm based on the networks and method described in the recent W2S paper to…

Image and Video Processing · Electrical Eng. & Systems 2020-04-24 Martin Chatton

While functional Magnetic Resonance Imaging (fMRI) offers valuable insights into cognitive processes, its inherent spatial limitations pose challenges for detailed analysis of the fine-grained functional architecture of the brain. More…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Fernando Pérez-Bueno , Hongwei Bran Li , Matthew S. Rosen , Shahin Nasr , Cesar Caballero-Gaudes , Juan Eugenio Iglesias

Diffusion bridges (DBs) are a class of diffusion models that enable faster sampling by interpolating between two paired image distributions. Training traditional DBs for image reconstruction requires high-quality reference images, which…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Harry Gao , Weijie Gan , Yuyang Hu , Hongyu An , Ulugbek S. Kamilov

Image deblurring is an ill-posed problem with multiple plausible solutions for a given input image. However, most existing methods produce a deterministic estimate of the clean image and are trained to minimize pixel-level distortion. These…

Computer Vision and Pattern Recognition · Computer Science 2021-12-30 Jay Whang , Mauricio Delbracio , Hossein Talebi , Chitwan Saharia , Alexandros G. Dimakis , Peyman Milanfar

We propose a simple all-in-line single-shot scheme for diagnostics of ultrashort laser pulses, consisting of a multi-mode fiber, a nonlinear crystal and a CCD camera. The system records a 2D spatial intensity pattern, from which the pulse…

Sub-diffraction resolution imaging has played a pivotal role in biological research by visualizing key, but previously unresolvable, sub-cellular structures. Unfortunately, applications of far-field sub-diffraction resolution are currently…

Biological Physics · Physics 2017-05-02 Shwetadwip Chowdhury , Will J. Eldridge , Adam Wax , Joseph A. Izatt

We propose an unfolded accelerated projected-gradient descent procedure to estimate model and algorithmic parameters for image super-resolution and molecule localization problems in image microscopy. The variational lower-level constraint…

Numerical Analysis · Mathematics 2024-03-27 Silvia Bonettini , Luca Calatroni , Danilo Pezzi , Marco Prato

Deep learning has shown great potential in accelerating diffusion tensor imaging (DTI). Nevertheless, existing methods tend to suffer from Rician noise and eddy current, leading to detail loss in reconstructing the DTI-derived parametric…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Wenxin Fan , Jian Cheng , Cheng Li , Jing Yang , Ruoyou Wu , Juan Zou , Shanshan Wang

Functional MRI (fMRI) is commonly used for interpreting neural activities across the brain. Numerous accelerated fMRI techniques aim to provide improved spatiotemporal resolutions. Among these, simultaneous multi-slice (SMS) imaging has…

Image and Video Processing · Electrical Eng. & Systems 2021-05-11 Omer Burak Demirel , Burhaneddin Yaman , Logan Dowdle , Steen Moeller , Luca Vizioli , Essa Yacoub , John Strupp , Cheryl A. Olman , Kâmil Uğurbil , Mehmet Akçakaya

Modern technology for producing extremely bright and coherent X-ray laser pulses provides the possibility to acquire a large number of diffraction patterns from individual biological nanoparticles, including proteins, viruses, and DNA.…

Methodology · Statistics 2018-07-11 Stefan Engblom , Carl Nettelblad , Jing Liu

In this paper, we present a novel approach to accelerate the Bayesian inference process, focusing specifically on the nested sampling algorithms. Bayesian inference plays a crucial role in cosmological parameter estimation, providing a…

Instrumentation and Methods for Astrophysics · Physics 2024-10-17 Isidro Gómez-Vargas , J. Alberto Vázquez

While single-image super-resolution (SISR) has attracted substantial interest in recent years, the proposed approaches are limited to learning image priors in order to add high frequency details. In contrast, multi-frame super-resolution…

Computer Vision and Pattern Recognition · Computer Science 2021-04-07 Goutam Bhat , Martin Danelljan , Luc Van Gool , Radu Timofte