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We exploit a simple one-dimensional trapping model introduced before, prompted by the problem of ion current across a biological membrane. The voltage-sensitive channels are open or closed depending on the value taken by an external…

Statistical Mechanics · Physics 2009-11-07 J. A. Revelli , A. D. Sanchez , H. S. Wio

We study an open-chain totally asymmetric exclusion process (TASEP) with stochastic gates present at the two boundaries. The gating dynamics has been modeled keeping the physical system of ion-channel gating in mind. These gates can…

Statistical Mechanics · Physics 2014-10-16 Mithun Kumar Mitra , Sakuntala Chatterjee

The action potential signal of nerve and muscle is produced by voltage sensitive channels that include a specialized device to sense voltage. Gating currents of the voltage sensor are now known to depend on the back-and-forth movements of…

Biological Physics · Physics 2017-07-11 Tzyy-Leng Horng , Robert S. Eisenberg , Chun Liu , Francisco Bezanilla

A Poisson-Nernst-Planck-Fermi (PNPF) theory is developed for studying ionic transport through biological ion channels. Our goal is to deal with the finite size of particle using a Fermi like distribution without calculating the forces…

Biological Physics · Physics 2015-06-23 Jinn-Liang Liu , Bob Eisenberg

For low enough flow rates, turbulent channel flow displays spatial modulations of large wavelengths. This phenomenon has recently been interpreted as a linear instability of the turbulent flow. We question here the ability of linear…

Fluid Dynamics · Physics 2024-06-21 P. V. Kashyap , Y. Duguet , O. Dauchot

This is an early but comprehensive review of the PNP Poisson Nernst Planck theory of ion channels. Extensive reference is made to the earlier literature. The starting place for this theory of open channels is a theory of electrodiffusion…

Biomolecules · Quantitative Biology 2010-09-16 Bob Eisenberg

Understanding the system-level spectral immittance response of capacitive energy storage devices with analytically tractable physics-based models is not only important for the progress of the technology, but also allows to develop new…

Applied Physics · Physics 2022-02-22 Anis Allagui , Hachemi Benaoum , Hichem Eleuch , Chunlei Wang

Boolean networks are discrete dynamical systems in which the state (zero or one) of each node is updated at each time t to a state determined by the states at time t-1 of those nodes that have links to it. When these systems are used to…

Molecular Networks · Quantitative Biology 2012-02-28 Andrew Pomerance , Michelle Girvan , Ed Ott

Ion transport through narrow channels is described by the coupled Poisson--Nernst--Planck--Stokes equations (PNPS) on a continuum scale. However, direct numerical simulations in two or three dimensions of boundary value problems for small…

Analysis of PDEs · Mathematics 2026-03-10 Christine Keller , Andreas Münch , Barbara Wagner

This study investigates the flux ratios of ionic flows using Poisson-Nernst-Planck (PNP) models. The flux ratio measures the effect of permanent charge on the ion fluxes and can exhibit bifurcation, where a small parameter change causes a…

Dynamical Systems · Mathematics 2023-11-07 Hamid Mofidi

The stochastic mutual repressor model is analysed using perturbation methods. This simple model of a gene circuit consists of two genes and three promotor states. Either of the two protein products can dimerize, forming a repressor molecule…

Biological Physics · Physics 2014-06-12 Jay Newby

We investigate the stabilization of unstable multidimensional partially observed single-sensor and multi-sensor linear systems driven by unbounded noise and controlled over discrete noiseless channels under fixed-rate information…

Optimization and Control · Mathematics 2012-09-21 Andrew P. Johnston , Serdar Yüksel

Kinetic equations for the stationary state distribution function of ions moving through narrow pores are solved for a number of one-dimensional models of single ion transport. Ions move through pores of length $L$, under the action of a…

Soft Condensed Matter · Physics 2009-11-10 Jaroslaw Piasecki , Rosalind J. Allen , Jean-Pierre Hansen

Networks of channels conveying particles are often subject to blockages due to the limited carrying capacity of the individual channels. If the channels are coupled, blockage of one causes an increase in the flux entering the remaining open…

Statistical Mechanics · Physics 2019-06-28 Chloé Barré , Gregory Page , Julian Talbot , Pascal Viot

An anomalous diffusion model for ion channel gating is put forward. This scheme is able to describe non-exponential, power-law like distributions of residence time intervals in several types of ion channels. Our method presents a…

Biological Physics · Physics 2007-05-23 Igor Goychuk , Peter Hanggi

We discuss various models of ion transport through cell membrane channels. Recent experimental data shows that sizes of ion channels are compared to those of ions and that only few ions may be simultaneously in any single channel.…

Subcellular Processes · Quantitative Biology 2007-06-06 Jan Gomulkiewicz , Jacek Miekisz , Stanislaw Miekisz

Recurrent neural networks (RNNs) are powerful dynamical models, widely used in machine learning (ML) and neuroscience. Prior theoretical work has focused on RNNs with additive interactions. However, gating - i.e. multiplicative -…

Disordered Systems and Neural Networks · Physics 2021-12-02 Kamesh Krishnamurthy , Tankut Can , David J. Schwab

We investigate channel-confined, nematic liquid crystals using the Beris-Edwards model of nematohydrodynamics. Using strong homeotropic anchoring at the walls, we find multistability i.e. multiple coexisting states where the uniform nematic…

Soft Condensed Matter · Physics 2025-11-19 Rahil N. Valani , Sumesh Thampi , Julia M. Yeomans

Stabilization of non-stationary linear systems over noisy communication channels is considered. Stochastically stable sources, and unstable but noise-free or bounded-noise systems have been extensively studied in information theory and…

Information Theory · Computer Science 2012-05-07 Serdar Yüksel

Transitions between multiple stable states of nonlinear systems are ubiquitous in physics, chemistry, and beyond. Two types of behaviors are usually seen as mutually exclusive: unpredictable noise-induced transitions and predictable…

Statistical Mechanics · Physics 2017-10-03 Corentin Herbert , Freddy Bouchet