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A major limitation of machine learning (ML) prediction models is that they recover associational, rather than causal, predictive relationships between variables. In high-stakes automation applications of ML this is problematic, as the model…

Machine Learning · Computer Science 2025-11-04 Jianqiao Mao , Max A. Little

Causal discovery algorithms allow for the inference of causal structures from probabilistic relations of random variables. A natural field for the application of this tool is quantum mechanics, where a long-standing debate about the role of…

Quantum Physics · Physics 2018-04-19 R. Rossi

The notion of causality is used in many situations dealing with uncertainty. We consider the problem whether causality can be identified given data set generated by discrete random variables rather than continuous ones. In particular, for…

Machine Learning · Statistics 2014-01-23 Joe Suzuki , Takanori Inazumi , Takashi Washio , Shohei Shimizu

Causal discovery, the problem of inferring the direction of causality, is generally ill-posed. We use the language of structural causal models (SCM) to show that assuming that the causal relations are acyclic and invariant across multiple…

Machine Learning · Statistics 2026-05-14 Francesco Montagna , Francesco Locatello

Causal inference in observational studies with high-dimensional covariates presents significant challenges. We introduce CausalBGM, an AI-powered Bayesian generative modeling approach that captures the causal relationship among covariates,…

Machine Learning · Statistics 2026-02-23 Qiao Liu , Wing Hung Wong

Distinguishing cause from effect using observations of a pair of random variables is a core problem in causal discovery. Most approaches proposed for this task, namely additive noise models (ANM), are only adequate for quantitative data. We…

Machine Learning · Computer Science 2023-03-16 Mário A. T. Figueiredo , Catarina A. Oliveira

This paper serves as a starting point for machine learning researchers, engineers and students who are interested in but not yet familiar with causal inference. We start by laying out an important set of assumptions that are collectively…

Machine Learning · Computer Science 2024-08-28 Daniel Jiwoong Im , Kyunghyun Cho

In causal inference, it is common to estimate the causal effect of a single treatment variable on an outcome. However, practitioners may also be interested in the effect of simultaneous interventions on multiple covariates of a fixed target…

Methodology · Statistics 2022-11-24 Jaime Roquero Gimenez , Dominik Rothenhäusler

The goal of Causal Discovery is to find automated search methods for learning causal structures from observational data. In some cases all variables of the interested causal mechanism are measured, and the task is to predict the effects one…

Machine Learning · Statistics 2024-01-11 Shuyan Wang

Learning disentangled causal representations is a challenging problem that has gained significant attention recently due to its implications for extracting meaningful information for downstream tasks. In this work, we define a new notion of…

Machine Learning · Computer Science 2024-08-27 Aneesh Komanduri , Yongkai Wu , Feng Chen , Xintao Wu

Much of scientific data is collected as randomized experiments intervening on some and observing other variables of interest. Quite often, a given phenomenon is investigated in several studies, and different sets of variables are involved…

Methodology · Statistics 2012-10-19 Antti Hyttinen , Frederick Eberhardt , Patrik O. Hoyer

Large Language Models (LLMs) offer a flexible means to generate synthetic tabular data, yet existing approaches often fail to preserve key causal parameters such as the average treatment effect (ATE). In this technical exploration, we first…

Machine Learning · Computer Science 2025-11-04 Dana Kim , Yichen Xu , Tiffany Lin

Designing studies that apply causal discovery requires navigating many researcher degrees of freedom. This complexity is exacerbated when the study involves fMRI data. In this paper we (i) describe nine challenges that occur when applying…

Quantitative Methods · Quantitative Biology 2023-12-21 Eric Rawls , Bryan Andrews , Kelvin Lim , Erich Kummerfeld

The inaccessibility of controlled randomized trials due to inherent constraints in many fields of science has been a fundamental issue in causal inference. In this paper, we focus on distinguishing the cause from effect in the bivariate…

Machine Learning · Statistics 2021-02-23 Jean-Francois Ton , Dino Sejdinovic , Kenji Fukumizu

Classical machine learning techniques often struggle with overfitting and unreliable predictions when exposed to novel conditions. Introducing causality into the modelling process offers a promising way to mitigate these challenges by…

Computational Engineering, Finance, and Science · Computer Science 2025-05-28 David Zapata Gonzalez , Marcel Meyer , Oliver Mueller

Unraveling the causal relationships among the execution of process activities is a crucial element in predicting the consequences of process interventions and making informed decisions regarding process improvements. Process discovery…

Artificial Intelligence · Computer Science 2025-01-15 Fabiana Fournier , Lior Limonad , Inna Skarbovsky , Yuval David

Bivariate causal direction identification is a fundamental and vital problem in the causal inference field. Among binary causal methods, most methods based on additive noise only use one single causal mechanism to construct a causal model.…

Artificial Intelligence · Computer Science 2025-07-30 Saixiong Liu , Yuhua Qian , Jue Li , Honghong Cheng , Feijiang Li

Causal discovery is an imperative foundation for decision-making across domains, such as smart health, AI for drug discovery and AIOps. Traditional statistical causal discovery methods, while well-established, predominantly rely on…

Machine Learning · Computer Science 2025-06-03 ChengAo Shen , Zhengzhang Chen , Dongsheng Luo , Dongkuan Xu , Haifeng Chen , Jingchao Ni

The assumption of independence between observations (units) in a dataset is prevalent across various methodologies for learning causal graphical models. However, this assumption often finds itself in conflict with real-world data, posing…

Machine Learning · Computer Science 2024-12-31 Alex Chen , Qing Zhou

To discover new drugs is to seek and to prove causality. As an emerging approach leveraging human knowledge and creativity, data, and machine intelligence, causal inference holds the promise of reducing cognitive bias and improving decision…

Quantitative Methods · Quantitative Biology 2025-04-09 Tom Michoel , Jitao David Zhang