English
Related papers

Related papers: Haplotype-aware graph indexes

200 papers

The explosion of data throughout the biomedical sciences provides unprecedented opportunities to learn about the dynamics of evolution and disease progression, but harnessing these large and diverse datasets remains challenging. Here, we…

Quantitative Methods · Quantitative Biology 2019-12-03 Sam F. Greenbury , Mauricio Barahona , Iain G. Johnston

The classification of high-dimensional data defined on graphs is particularly difficult when the graph geometry is unknown. We introduce a Haar scattering transform on graphs, which computes invariant signal descriptors. It is implemented…

Machine Learning · Computer Science 2014-11-04 Xu Chen , Xiuyuan Cheng , Stéphane Mallat

Diabetes is a worldwide health issue affecting millions of people. Machine learning methods have shown promising results in improving diabetes prediction, particularly through the analysis of diverse data types, namely gene expression data.…

Machine Learning · Computer Science 2024-04-24 Rita T. Sousa , Heiko Paulheim

Vector data is prevalent across business and scientific applications, and its popularity is growing with the proliferation of learned embeddings. Vector data collections often reach billions of vectors with thousands of dimensions, thus,…

Information Retrieval · Computer Science 2025-09-09 Ilias Azizi , Karima Echihab , Themis Palpanas , Vassilis Christophides

Graph Neural Networks (GNNs) are popular machine learning methods for modeling graph data. A lot of GNNs perform well on homophily graphs while having unsatisfactory performance on heterophily graphs. Recently, some researchers turn their…

Machine Learning · Computer Science 2022-09-20 Wendong Bi , Lun Du , Qiang Fu , Yanlin Wang , Shi Han , Dongmei Zhang

Generating graph structures is a challenging problem due to the diverse representations and complex dependencies among nodes. In this paper, we introduce Graph Variational Recurrent Neural Network (GraphVRNN), a probabilistic autoregressive…

Machine Learning · Computer Science 2019-10-07 Shih-Yang Su , Hossein Hajimirsadeghi , Greg Mori

The graph isomorphism problem looks deceptively simple, but although polynomial-time algorithms exist for certain types of graphs such as planar graphs and graphs with bounded degree or eigenvalue multiplicity, its complexity class is still…

Discrete Mathematics · Computer Science 2025-07-11 Stefan Klus , Patrick Gelß

Genotype networks are a method used in systems biology to study the "innovability" of a set of genotypes having the same phenotype. In the past they have been applied to determine the genetic heterogeneity, and stability to mutations, of…

Populations and Evolution · Quantitative Biology 2015-06-17 Giovanni Marco Dall'Olio , Jaume Bertranpetit , Andreas Wagner , Hafid Laayouni

Graph Neural Networks (GNNs) excel at analyzing graph-structured data but struggle on heterophilic graphs, where connected nodes often belong to different classes. While this challenge is commonly addressed with specialized GNN…

Machine Learning · Computer Science 2025-05-20 Harel Mendelman , Haggai Maron , Ronen Talmon

Heterophilic Graph Neural Networks (HGNNs) have shown promising results for semi-supervised learning tasks on graphs. Notably, most real-world heterophilic graphs are composed of a mixture of nodes with different neighbor patterns,…

Machine Learning · Computer Science 2025-02-26 Jinluan Yang , Zhengyu Chen , Teng Xiao , Wenqiao Zhang , Yong Lin , Kun Kuang

In this paper we introduce a novel polynomial-time algorithm to compute graph invariants based on the modified random walk idea on graphs. However not proved to be a full graph invariant by now, our method gives the right answer for the…

Data Structures and Algorithms · Computer Science 2015-08-24 Alexander Gamkrelidze , Gunter Hotz , Levan Varamashvili

In genome-wide prediction, independence of marker allele substitution effects is typically assumed; however, since early stages of this technology it has been known that nature points to correlated effects. In statistics, graphical models…

Quantitative Methods · Quantitative Biology 2017-09-21 Carlos Alberto Martínez , Kshitij Khare , Syed Rahman , Mauricio A. Elzo

Graph neural networks (GNNs) have emerged as a powerful tool for modeling graph-structured data. However, existing GNNs often struggle with heterophilic graphs, where connected nodes tend to have dissimilar features or labels. While…

Machine Learning · Computer Science 2026-02-10 Ruizhong Qiu , Ting-Wei Li , Gaotang Li , Hanghang Tong

Many processes, from gene interaction in biology to computer networks to social media, can be modeled more precisely as temporal hypergraphs than by regular graphs. This is because hypergraphs generalize graphs by extending edges to connect…

Human-Computer Interaction · Computer Science 2021-05-12 Maximilian T. Fischer , Devanshu Arya , Dirk Streeb , Daniel Seebacher , Daniel A. Keim , Marcel Worring

Learning generative models for graph-structured data is challenging because graphs are discrete, combinatorial, and the underlying data distribution is invariant to the ordering of nodes. However, most of the existing generative models for…

Machine Learning · Computer Science 2020-03-03 Chenhao Niu , Yang Song , Jiaming Song , Shengjia Zhao , Aditya Grover , Stefano Ermon

In recent years, non-parametric methods utilizing random walks on graphs have been used to solve a wide range of machine learning problems, but in their simplest form they do not scale well due to the quadratic complexity. In this paper, a…

Machine Learning · Computer Science 2012-10-19 Saeed Amizadeh , Bo Thiesson , Milos Hauskrecht

Current graph neural networks (GNNs) lack generalizability with respect to scales (graph sizes, graph diameters, edge weights, etc..) when solving many graph analysis problems. Taking the perspective of synthesizing graph theory programs,…

Machine Learning · Computer Science 2020-10-27 Hao Tang , Zhiao Huang , Jiayuan Gu , Bao-Liang Lu , Hao Su

Transformers have recently emerged as powerful neural networks for graph learning, showcasing state-of-the-art performance on several graph property prediction tasks. However, these results have been limited to small-scale graphs, where the…

Machine Learning · Computer Science 2023-12-19 Vijay Prakash Dwivedi , Yozen Liu , Anh Tuan Luu , Xavier Bresson , Neil Shah , Tong Zhao

In recent years, graph neural networks (GNNs) have gained increasing attention, as they possess the excellent capability of processing graph-related problems. In practice, hyperparameter optimisation (HPO) is critical for GNNs to achieve…

Machine Learning · Computer Science 2021-04-29 Yingfang Yuan , Wenjun Wang , Wei Pang

Recent advances in biological technologies, such as multi-way chromosome conformation capture (3C), require development of methods for analysis of multi-way interactions. Hypergraphs are mathematically tractable objects that can be utilized…

Quantitative Methods · Quantitative Biology 2023-07-19 Joshua Pickard , Can Chen , Rahmy Salman , Cooper Stansbury , Sion Kim , Amit Surana , Anthony Bloch , Indika Rajapakse