Related papers: Minimum Segmentation for Pan-genomic Founder Recon…
A common problem in phylogenetics is to try to infer a species phylogeny from gene trees. We consider different variants of this problem. The first variant, called Unrestricted Minimal Episodes Inference, aims at inferring a species tree…
Sequence segmentation is a well-studied problem, where given a sequence of elements, an integer K, and some measure of homogeneity, the task is to split the sequence into K contiguous segments that are maximally homogeneous. A classic…
We study the problem of reconfiguring one minimum $s$-$t$-separator $A$ into another minimum $s$-$t$-separator $B$ in some $n$-vertex graph $G$ containing two non-adjacent vertices $s$ and $t$. We consider several variants of the problem as…
Approximate nearest-neighbor search is a fundamental algorithmic problem that continues to inspire study due its essential role in numerous contexts. In contrast to most prior work, which has focused on point sets, we consider…
Genome sequencing is the basis for many modern biological and medicinal studies. With recent technological advances, metagenomics has become a problem of interest. This problem entails the analysis and reconstruction of multiple DNA…
We study the Requirement Cut problem, a generalization of numerous classical graph partitioning problems including Multicut, Multiway Cut, $k$-Cut, and Steiner Multicut among others. Given a graph with edge costs, terminal groups $(S_1,…
We address a fundamental problem arising from analysis of biomolecular sequences. The input consists of two numbers $w_{\min}$ and $w_{\max}$ and a sequence $S$ of $n$ number pairs $(a_i,w_i)$ with $w_i>0$. Let {\em segment} $S(i,j)$ of $S$…
In this paper we consider the problem of finding a vector that can be written as a nonnegative integer linear combination of given 0-1 vectors, the generators, such that the l_1-distance between this vector and a given target vector is…
In this paper, we present new efficiently solvable cases of the Minimum Uncovering Branching problem, an optimization problem with applications in cancer genomics introduced by Hujdurovi\'c, Husi\'c, Milani\v{c}, Rizzi, and Tomescu in 2018.…
\ac{fl} proposed a distributed \ac{ml} framework where every distributed worker owns a complete copy of global model and their own data. The training is occurred locally, which assures no direct transmission of training data. However, the…
The palindromic fingerprint of a string $S[1\ldots n]$ is the set $PF(S) = \{(i,j)~|~ S[i\ldots j] \textit{ is a maximal }\\ \textit{palindrome substring of } S\}$. In this work, we consider the problem of string reconstruction from a…
The study of genetic map linearization leads to a combinatorial hard problem, called the {\em minimum breakpoint linearization} (MBL) problem. It is aimed at finding a linearization of a partial order which attains the minimum breakpoint…
We consider compact representations of collections of similar strings that support random access queries. The collection of strings is given by a rooted tree where edges are labeled by an edit operation (inserting, deleting, or replacing a…
We study the problem of finding a maximum cardinality minimal separator of a graph. This problem is known to be NP-hard even for bipartite graphs. In this paper, we strengthen this hardness by showing that for planar bipartite graphs, the…
In the (deletion-channel) trace reconstruction problem, there is an unknown $n$-bit source string $x$. An algorithm is given access to independent traces of $x$, where a trace is formed by deleting each bit of~$x$ independently with…
We study graph partitioning problems from a min-max perspective, in which an input graph on n vertices should be partitioned into k parts, and the objective is to minimize the maximum number of edges leaving a single part. The two main…
In this paper we present a collection of results pertaining to haplotyping. The first set of results concerns the combinatorial problem of reconstructing haplotypes from incomplete and/or imperfectly sequenced haplotype data. More…
We study the complexity of the following cell connection and separation problems in segment arrangements. Given a set of straight-line segments in the plane and two points $a$ and $b$ in different cells of the induced arrangement: (i)…
We revisit the classical problem of Fourier-sparse signal reconstruction -- a variant of the \emph{Set Query} problem -- which asks to efficiently reconstruct (a subset of) a $d$-dimensional Fourier-sparse signal ($\|\hat{x}(t)\|_0 \leq…
The transversal hypergraph problem is the task of enumerating the minimal hitting sets of a hypergraph. It is a long-standing open question whether this can be done in output-polynomial time. For hypergraphs whose solutions have bounded…