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A critical decision point when training predictors using multiple studies is whether studies should be combined or treated separately. We compare two multi-study prediction approaches in the presence of potential heterogeneity in…

Machine Learning · Statistics 2024-12-13 Zoe Guan , Giovanni Parmigiani , Prasad Patil

Transfer learning is beneficial for survival analysis, especially when the target study has a limited number of events. However, existing transfer learning methods rely on the restrictive assumption that the target and source studies share…

Methodology · Statistics 2026-03-13 Yu Gu , Donglin Zeng , D. Y. Lin

Discrimination and calibration represent two important properties of survival analysis, with the former assessing the model's ability to accurately rank subjects and the latter evaluating the alignment of predicted outcomes with actual…

Machine Learning · Computer Science 2024-06-04 Shi-ang Qi , Yakun Yu , Russell Greiner

The conditional survival function of a time-to-event outcome subject to censoring and truncation is a common target of estimation in survival analysis. This parameter may be of scientific interest and also often appears as a nuisance in…

Methodology · Statistics 2024-08-20 Charles J. Wolock , Peter B. Gilbert , Noah Simon , Marco Carone

From the formation of ice in small clusters of water molecules to the mass raids of army ant colonies, the emergent behavior of collectives depends critically on their size. At the same time, common wisdom holds that such behaviors are…

Populations and Evolution · Quantitative Biology 2025-10-08 Jacob Calvert , Andréa W. Richa , Dana Randall

Predictions about people, such as their expected educational achievement or their credit risk, can be performative and shape the outcome that they aim to predict. Understanding the causal effect of these predictions on the eventual outcomes…

Machine Learning · Statistics 2022-10-19 Celestine Mendler-Dünner , Frances Ding , Yixin Wang

Sensitivity analysis is widely used to assess the robustness of causal conclusions in observational studies, yet its interaction with the structure of measured covariates is often overlooked. When latent confounders cannot be directly…

Methodology · Statistics 2026-02-17 Abhinandan Dalal , Iris Horng , Yang Feng , Dylan S. Small

Causal inference with observational studies often suffers from unmeasured confounding, yielding biased estimators based on the unconfoundedness assumption. Sensitivity analysis assesses how the causal conclusions change with respect to…

Methodology · Statistics 2024-04-01 Sizhu Lu , Peng Ding

Biological organisms are open, adaptve systems that can respond to changes in environment in specific ways. Adaptation and response can be posed as an optimization problem, with a tradeoff between the benefit obtained from a response and…

Statistical Mechanics · Physics 2018-10-17 Suman G. Das , Madan Rao , Garud Iyengar

Cross-validation is a popular non-parametric method for evaluating the accuracy of a predictive rule. The usefulness of cross-validation depends on the task we want to employ it for. In this note, I discuss a simple non-parametric setting,…

Methodology · Statistics 2019-09-27 Stefan Wager

Spurious correlations occur when a model learns unreliable features from the data and are a well-known drawback of data-driven learning. Although there are several algorithms proposed to mitigate it, we are yet to jointly derive the…

Machine Learning · Computer Science 2023-08-23 Gautam Sreekumar , Vishnu Naresh Boddeti

In recent years, the growing availability of biomedical datasets featuring numerous longitudinal covariates has motivated the development of several multi-step methods for the dynamic prediction of survival outcomes. These methods employ…

Methodology · Statistics 2026-01-14 Mirko Signorelli , Sophie Retif

We study multiple change-points detection using multi-samples tests based on U-statistics for absolutely regular observations. Our results extend those of Ngatchou-Wandji et al. (2022) concerned with the study of one single changepoint. The…

Statistics Theory · Mathematics 2025-11-25 Joseph Ngatchou-Wandji , Echarif Elharfaoui , Michel Harel

We propose a change-point detection method for large scale multiple testing problems with data having clustered signals. Unlike the classic change-point setup, the signals can vary in size within a cluster. The clustering structure on the…

Methodology · Statistics 2021-10-07 Hongyuan Cao , Wei Biao Wu

The prediction of surrounding traffic participants behavior is a crucial and challenging task for driver assistance and autonomous driving systems. Today's approaches mainly focus on modeling dynamic aspects of the traffic situation and try…

Computers and Society · Computer Science 2021-10-27 Florian Wirthmüller , Jochen Hipp , Christian Reichenbächer , Manfred Reichert

Delayed separation of survival curves is a common occurrence in confirmatory studies in immuno-oncology. Many novel statistical methods that aim to efficiently capture potential long-term survival improvements have been proposed in recent…

Methodology · Statistics 2022-01-26 Dominic Magirr , José L. Jiménez

Conventional survival metrics, such as Harrell's concordance index (CI) and the Brier Score, rely on the independent censoring assumption for valid inference with right-censored data. However, in the presence of so-called dependent…

Machine Learning · Statistics 2025-05-20 Christian Marius Lillelund , Shi-ang Qi , Russell Greiner

Time series, as frequently the case in neuroscience, are rarely stationary, but often exhibit abrupt changes due to attractor transitions or bifurcations in the dynamical systems producing them. A plethora of methods for detecting such…

Methodology · Statistics 2018-10-05 Hazem Toutounji , Daniel Durstewitz

It has long been hypothesized that operating close to the critical state is beneficial for natural, artificial and their evolutionary systems. We put this hypothesis to test in a system of evolving foraging agents controlled by neural…

Neural and Evolutionary Computing · Computer Science 2023-11-28 Sina Khajehabdollahi , Jan Prosi , Emmanouil Giannakakis , Georg Martius , Anna Levina

Investigation of the critical levels and catastrophes in the complex systems of different nature is useful and perspective. Mathematical modeling and analysis is presented for revealing and investigation of the phenomena and critical levels…

Adaptation and Self-Organizing Systems · Physics 2017-04-06 Ivan V. Kazachkov