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The mechanical properties within living cells play a critical role in the adaptive regulation of their biological functions upon environmental and internal stimuli. While these properties exhibit nonequilibrium dynamics due to the thermal…

Biological Physics · Physics 2024-08-14 Yuika Ueda , Shinji Deguchi

We propose a model for the dynamics of a probe embedded in a living cell, where both thermal fluctuations and nonequilibrium activity coexist. The model is based on a confining harmonic potential describing the elastic cytoskeletal matrix,…

Biological Physics · Physics 2015-06-18 É. Fodor , M. Guo , N. S. Gov , P. Visco , D. A. Weitz , F. van Wijland

Many-body systems relaxing to equilibrium can exhibit complex dynamics even if their steady state is trivial. At low temperatures or high densities their evolution is often dominated by steric hindrances affecting particle motion [1,2,3].…

Statistical Mechanics · Physics 2016-05-10 M. M. Valado , C. Simonelli , M. D. Hoogerland , I. Lesanovsky , J. P. Garrahan , E. Arimondo , D. Ciampini , O. Morsch

It is now widely recognized that mechanical interactions between cells play a crucial role in epithelial morphogenesis, yet understanding the mechanisms through which stress and deformation affect cell behavior remains an open problem due…

Tissues and Organs · Quantitative Biology 2017-01-20 Nicholas Noll , Madhav Mani , Idse Heemskerk , Sebastian Streichan , Boris I. Shraiman

An irreversible thermodynamical theory of solids is presented where the kinematic quantities are defined in an automatically objective way. Namely, auxiliary elements like reference frame, reference time and reference configuration are…

Classical Physics · Physics 2015-12-22 Tamás Fülöp

A 1D model of interacting particles moving over a periodic substrate and in a position dependent temperature profile is considered. When the substrate and the temperature profile are spatially asymmetric a center-of-mass velocity develops,…

Statistical Mechanics · Physics 2021-03-03 A. Imparato

For a circuit made of thermodynamic devices in stationary nonequilibrium, we determine the mean currents (of energy, matter, charge, etc) exchanged with external reservoirs driving the circuit out of equilibrium. Starting from the…

Statistical Mechanics · Physics 2024-05-03 Paul Raux , Christophe Goupil , Gatien Verley

The model analyzes the muscle fiber as a deformable system for which experimental data are determinated with the help of the laws of Newtonian mechanic. The model predicts the four transient phases for the shortening of a muscle fiber…

Tissues and Organs · Quantitative Biology 2013-11-19 Sylvain Louvet

Thermally actuated twisted and coiled polymer (TCP) artificial muscles exhibit exceptional specific work capacities but are limited by an inherent competition between load-bearing capacity and actuation stroke. To address this limitation,…

Soft Condensed Matter · Physics 2026-02-09 Ye Xiao , Zhao Luo , Falin Tian , Xinghao Hu , Dabiao Liu , Chun Li

The Electrocardiograph signal represents the heart's electrical activity while blood pressure results from the heart's mechanical activity. Previous studies have investigated how the heart's electrical and mechanical activities are related…

Signal Processing · Electrical Eng. & Systems 2020-08-25 Seyedeh Somayyeh Mousavi , Mostafa Charmi , Mohammad Firouzmand , Mohammad Hemmati , Maryam Moghadam , Yadollah Ghorbani

The in silico simulations are widely used in contemporary systems biology including the analysis of nerve pulse propagation. As known from numerous experiments, the propagation of an action potential is accompanied by mechanical and thermal…

Biological Physics · Physics 2020-09-21 Jüri Engelbrecht , Kert Tamm , Tanel Peets

Using shear wave elastography, we measure the changes in the wave speed with the stress produced by a striated muscle during isometric voluntary contraction. To isolate the behaviour of an individual muscle from complementary or…

A unified thermodynamic framework for characterization of functional materials is developed. This framework encompasses linear reversible and irreversible processes with thermal, electrical, magnetic, and/or mechanical effects coupled. The…

Materials Science · Physics 2016-10-07 Sushma Santapuri

We consider a continuum model of active viscoelastic matter, whereby an active nematic liquid-crystal is coupled to a minimal model of polymer dynamics with a viscoelastic relaxation time $\tau_C$. To explore the resulting interplay between…

Soft Condensed Matter · Physics 2016-03-30 E. J. Hemingway , M. E. Cates , S. M. Fielding

The purpose of this study was to report numerical validation of a 3D finite element model of contracting muscle. The model was based on continuum theory for fibre-reinforced composite materials. Here we simulated contractions for an…

Quantitative Methods · Quantitative Biology 2015-04-03 Hadi Rahemi , Nilima Nigam , James M. Wakeling

Activity and renewability are distinctive features of living matter, and constitute a new class of materials that we term renewable active matter. A striking example is the cell cytoskeleton, where myosin filaments bind to the actin…

Soft Condensed Matter · Physics 2025-05-27 M. Abhishek , Ankit Dhanuka , Deb Sankar Banerjee , Madan Rao

Nonlinear thermoelastic systems play a crucial role in understanding thermal conductivity, stresses, elasticity, and temperature interactions. This research focuses on finding solutions to these systems in their fractional forms, which is a…

Analysis of PDEs · Mathematics 2025-01-13 Qasim Khan

Spatiotemporal patterns are common in biological systems. For electrically-coupled cells previous studies of pattern formation have mainly used external forcing as the main bifurcation parameter. The purpose of this paper is to show that…

Dynamical Systems · Mathematics 2021-11-02 H. O. Fatoyinbo , R. G. Brown , D. J. W. Simpson , B. van Brunt

Computer-based simulations of non-invasive cardiac electrical outputs, such as electrocardiograms and body surface potential maps, usually entail severe computational costs due to the need of capturing fine-scale processes and to the…

Numerical Analysis · Mathematics 2023-08-09 Elena Zappon , Andrea Manzoni , Alfio Quarteroni

The paper deals with the properties of thermally excited solitons of the isotropic spin-$S$ ferromagnetic chain with nearest-neighbor logarithmic interactions. The exact statistical mechanics of the interacting soliton gas is developed for…

Condensed Matter · Physics 2007-06-19 N. Theodorakopoulos