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We study the problem of finding maximal exact matches (MEMs) between a query string $Q$ and a labeled graph $G$. MEMs are an important class of seeds, often used in seed-chain-extend type of practical alignment methods because of their…

Data Structures and Algorithms · Computer Science 2023-07-04 Nicola Rizzo , Manuel Cáceres , Veli Mäkinen

We present several new results pertaining to haplotyping. These results concern the combinatorial problem of reconstructing haplotypes from incomplete and/or imperfectly sequenced haplotype fragments. We consider the complexity of the…

Genomics · Quantitative Biology 2016-11-17 Rudi Cilibrasi , Leo van Iersel , Steven Kelk , John Tromp

We study the minimum \emph{Monitoring Edge Geodetic Set} (\megset) problem introduced in [Foucaud et al., CALDAM'23]: given a graph $G$, we say that an edge is monitored by a pair $u,v$ of vertices if \emph{all} shortest paths between $u$…

Data Structures and Algorithms · Computer Science 2025-10-09 Davide Bilò , Giordano Colli , Luca Forlizzi , Stefano Leucci

The MEG (minimum equivalent graph) problem is, given a directed graph, to find a small subset of the edges that maintains all reachability relations between nodes. The problem is NP-hard. This paper gives a proof that, for graphs where each…

Data Structures and Algorithms · Computer Science 2015-06-02 Samir Khuller , Balaji Raghavachari , Neal Young

Recent matrix completion based methods have not been able to properly model the Haplotype Assembly Problem (HAP) for noisy observations. To cope with such a case, in this letter we propose a new Minimum Error Correction (MEC) based matrix…

Optimization and Control · Mathematics 2019-04-16 Mohamad Mahdi Mohades , Sina Majidian , Mohammad Hossein Kahaei

Given an undirected connected graph $G = (V(G), E(G))$ on $n$ vertices, the minimum Monitoring Edge-Geodetic Set (MEG-set) problem asks to find a subset $M \subseteq V(G)$ of minimum cardinality such that, for every edge $e \in E(G)$, there…

Computational Complexity · Computer Science 2024-05-24 Davide Bilò , Giordano Colli , Luca Forlizzi , Stefano Leucci

Multimodal data is a precious asset enabling a variety of downstream tasks in machine learning. However, real-world data collected across different modalities is often not paired, which is a significant challenge to learn a joint…

Machine Learning · Computer Science 2025-08-11 Mustapha Bounoua , Giulio Franzese , Pietro Michiardi

Sparsity constrained minimization captures a wide spectrum of applications in both machine learning and signal processing. This class of problems is difficult to solve since it is NP-hard and existing solutions are primarily based on…

Optimization and Control · Mathematics 2018-12-31 Ganzhao Yuan , Bernard Ghanem

In this paper we introduce and study the Minimum Edge Compact Spanner~(MECS) problem. We prove hardness results related to the problem, design exact and greedy algorithms for solving the problem, and show related experimental results. The…

Discrete Mathematics · Computer Science 2017-12-13 Tathagata Mukherjee , Alexander Veremyev , Piyush Kumar , Eduardo Pasiliao

Edge-Geodetic Sets play a crucial role in network monitoring and optimization, wherein the goal is to strategically place monitoring stations on vertices of a network, represented as a graph, to ensure complete coverage of edges and…

Computational Complexity · Computer Science 2025-06-17 Giordano Colli

In this thesis we develop FPTASs for the counting problems of m-tuples, contingency tables with two rows, and 0/1 knapsack. For the problem of counting m-tuples, we design two algorithms, one is strongly polynomial. As far as we know, these…

Data Structures and Algorithms · Computer Science 2016-11-04 Tzvi Alon

The MEG (minimum equivalent graph) problem is, given a directed graph, to find a small subset of the edges that maintains all reachability relations between nodes. The problem is NP-hard. This paper gives an approximation algorithm with…

Data Structures and Algorithms · Computer Science 2015-06-02 Samir Khuller , Balaji Raghavachari , Neal E. Young

The single nucleotide polymorphism (SNP) is the most widely studied type of genetic variation. A haplotype is defined as the sequence of alleles at SNP sites on each haploid chromosome. Haplotype information is essential in unravelling the…

Genomics · Quantitative Biology 2020-06-19 Sina Majidian , Mohammad Hossein Kahaei , Dick de Ridder

The area of parameterized approximation seeks to combine approximation and parameterized algorithms to obtain, e.g., (1+eps)-approximations in f(k,eps)n^{O(1)} time where k is some parameter of the input. We obtain the following results on…

Data Structures and Algorithms · Computer Science 2019-06-27 Fabrizio Grandoni , Stefan Kratsch , Andreas Wiese

The distinguishing result of this paper is a $\mathbf{P}$-time enumerable partition of all the potential perfect matchings in a bipartite graph. This partition is a set of equivalence classes induced by the missing edges in the potential…

Computational Complexity · Computer Science 2017-10-31 Javaid Aslam

Given an $n*n$ sparse symmetric matrix with $m$ nonzero entries, performing Gaussian elimination may turn some zeroes into nonzero values. To maintain the matrix sparse, we would like to minimize the number $k$ of these changes, hence…

Computational Complexity · Computer Science 2016-06-28 Yixin Cao , R. B. Sandeep

In this paper, we consider the packet-level forward error correction (FEC) code design, without feedback or with delayed feedback, for achieving the minimum end-to-end latency, i.e., the latency between the time when packet is generated at…

Information Theory · Computer Science 2020-01-08 Xiaoli Xu , Yong Zeng , Yonghui Li , Branka Vucetic

The main results of this paper provide an Efficient Polynomial-Time Approximation Scheme (EPTAS) for approximating the genus (and non-orientable genus) of dense graphs. By dense we mean that $|E(G)|\ge \alpha |V(G)|^2$ for some fixed…

Combinatorics · Mathematics 2024-08-28 Yifan Jing , Bojan Mohar

Recently, a so-called E-MS algorithm was developed for model selection in the presence of missing data. Specifically, it performs the Expectation step (E step) and Model Selection step (MS step) alternately to find the minimum point of the…

Methodology · Statistics 2021-06-22 Ping-Feng Xu , Lai-Xu Shang , Man-Lai Tang , Na Shan , Guoliang Tian

Max-value entropy search (MES) is one of the state-of-the-art approaches in Bayesian optimization (BO). In this paper, we propose a novel variant of MES for constrained problems, called Constrained MES via Information lower BOund…

Machine Learning · Computer Science 2023-02-21 Shion Takeno , Tomoyuki Tamura , Kazuki Shitara , Masayuki Karasuyama
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