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This study aims to investigate the effects of violations of the sphericity assumption on Type I error rates for different methodical approaches of repeated measures analysis using a simulation approach. In contrast to previous simulation…

Applications · Statistics 2017-04-26 Nicolas Haverkamp , Andre Beauducel

Linear mixed-effects models have increasingly replaced mixed-model analyses of variance for statistical inference in factorial psycholinguistic experiments. Although LMMs have many advantages over ANOVA, like ANOVAs, setting them up for…

Applications · Statistics 2017-02-14 Hannes Matuschek , Reinhold Kliegl , Shravan Vasishth , Harald Baayen , Douglas Bates

This paper proposes one of the first clinical applications of multimodal large language models (LLMs) as an assistant for radiologists to check errors in their reports. We created an evaluation dataset from real-world radiology datasets…

Computation and Language · Computer Science 2024-03-05 Jinge Wu , Yunsoo Kim , Eva C. Keller , Jamie Chow , Adam P. Levine , Nikolas Pontikos , Zina Ibrahim , Paul Taylor , Michelle C. Williams , Honghan Wu

We consider the problems of variable selection and estimation in nonparametric additive regression models for high-dimensional data. In recent years, several methods have been proposed to model nonlinear relationships when the number of…

Methodology · Statistics 2013-10-07 Linn Cecilie Bergersen , Kukatharmini Tharmaratnam , Ingrid K. Glad

Large language models (LLMs) are increasingly used to generate labels from radiology reports to enable large-scale AI evaluation. However, label noise from LLMs can introduce bias into performance estimates, especially under varying disease…

Through the lense of multilevel model (MLM) specification and regularization, this is a connect-the-dots introductory summary of Small Area Estimation, e.g. small group prediction informed by a complex sampling design. While a comprehensive…

Methodology · Statistics 2018-05-23 Michael Tzen

Representational Similarity Analysis (RSA) is a popular method for analyzing neuroimaging and behavioral data. Here we evaluate the accuracy and reliability of RSA in the context of model selection, and compare it to that of regression.…

Methodology · Statistics 2025-11-18 Chuanji Gao , Gang Chen , Svetlana V. Shinkareva , Rutvik H. Desai

Popular software packages report four generalizations of the ANOVA F test when conducting a multivariate analysis of variance (MANOVA). The reported operating characteristics of these fours tests vary widely depending on which research…

Computation · Statistics 2026-04-22 Joseph D Consiglio

Participants in clinical trials are often viewed as a unique, finite population. Yet, statistical analyses often assume that participants were randomly sampled from a larger population. Under Complete Randomization, Randomization-Based…

Methodology · Statistics 2025-10-09 Jonathan J. Chipman , Oleksandr Sverdlov , Diane Uschner

There is ongoing debate about whether large language models (LLMs) can serve as substitutes for human participants in survey and experimental research. While recent work in fields such as marketing and psychology has explored the potential…

Computation and Language · Computer Science 2025-12-30 Steven Wang , Kyle Hunt , Shaojie Tang , Kenneth Joseph

Background: Multicollinearity inflates the variance of OLS coefficients, widening confidence intervals and reducing inferential reliability. Yet fixed variance inflation factor (VIF) cut-offs are often applied uniformly across studies with…

Methodology · Statistics 2026-01-27 Stephanie CC van der Lubbe , Jose M Valderas , Evangelos Kontopantelis

Fine-tuning Large Language Models (LLMs) on specific datasets is a common practice to improve performance on target tasks. However, this performance gain often leads to overfitting, where the model becomes too specialized in either the task…

Computation and Language · Computer Science 2024-09-10 Sonam Gupta , Yatin Nandwani , Asaf Yehudai , Mayank Mishra , Gaurav Pandey , Dinesh Raghu , Sachindra Joshi

In randomized trials, repeated measures of the outcome are routinely collected. The mixed model for repeated measures (MMRM) leverages the information from these repeated outcome measures, and is often used for the primary analysis to…

Methodology · Statistics 2023-07-20 Bingkai Wang , Yu Du

Large Language Models (LLMs) are increasingly used to simulate social attitudes and behaviors, offering scalable "silicon samples" that can approximate human data. However, current simulation practice often collapses diversity into an…

Computers and Society · Computer Science 2026-04-09 Xiaoyou Qin , Zhihong Li , Xiaoxiao Cheng

The Hubble constant ($H_0$) is one of the fundamental parameters in cosmology, but there is a heated debate around the $>$4$\sigma$ tension between the local Cepheid distance ladder and the early Universe measurements. Strongly lensed Type…

Cosmology and Nongalactic Astrophysics · Physics 2022-03-14 S. Huber , S. H. Suyu , D. Ghoshdastidar , S. Taubenberger , V. Bonvin , J. H. H. Chan , M. Kromer , U. M. Noebauer , S. A. Sim , L. Leal-Taixé

Outcome-reward reinforcement learning (RL) is a common and increasingly significant way to refine the step-by-step reasoning of multimodal large language models (MLLMs). In the multiple-choice setting - a dominant format for multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Jiahao Wang , Weiye Xu , Aijun Yang , Wengang Zhou , Lewei Lu , Houqiang Li , Xiaohua Wang , Jinguo Zhu

Machine Learning (ML) models trained on complex health surveys such as the National Health and Nutrition Examination Survey (NHANES) often ignore primary sampling units, stratification variables, and sampling weights. This practice violates…

Machine Learning · Statistics 2026-05-12 YongKyung Oh , Henry W. Zheng , Jeffrey Feng , Alex A. T. Bui

In this paper, we investigate a multivariate multi-response (MVMR) linear regression problem, which contains multiple linear regression models with differently distributed design matrices, and different regression and output vectors. The…

Machine Learning · Computer Science 2013-07-31 Weiguang Wang , Yingbin Liang , Eric P. Xing

Magnetic Resonance Spectroscopy (MRS) is a noninvasive tool to reveal metabolic information. One challenge of 1H-MRS is the low Signal-Noise Ratio (SNR). To improve the SNR, a typical approach is to perform Signal Averaging (SA) with M…

Large language models are rapidly transforming social science research by enabling the automation of labor-intensive tasks like data annotation and text analysis. However, LLM outputs vary significantly depending on the implementation…

Computation and Language · Computer Science 2025-10-07 Joachim Baumann , Paul Röttger , Aleksandra Urman , Albert Wendsjö , Flor Miriam Plaza-del-Arco , Johannes B. Gruber , Dirk Hovy
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