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Purpose: The purpose of this work was to provide a flexible platform for FLASH research with protons by adapting a former clinical pencil beam scanning gantry to irradiations with ultrahigh dose rates. Methods: PSI Gantry 1 treated patients…

Quantum tomography is the main method used to assess the quality of quantum information processing devices, but its complexity presents a major obstacle for the characterization of even moderately large systems. The number of experimental…

Quantum Physics · Physics 2015-03-19 Marcus P. da Silva , Olivier Landon-Cardinal , David Poulin

We propose a method to achieve the geometric calibration of cone-beam imaging and delivery systems in radiation therapy; our approach applies to devices where an X-ray source and a flat-panel detector, facing each other, move in circular…

Medical Physics · Physics 2007-05-23 Evangelos Matsinos , Wolfgang Kaissl

Quantum imaging is emerging as a transformative approach for biomedical applications, applying nonclassical properties of light, such as entanglement, squeezing, and quantum correlations, to overcome fundamental limits of conventional…

The principle of the momentum computed tomography of charged particles is presented. It may be useful for momentum spectroscopy of various beam-matter interactions, especially when very intense beams are involved. It is able to collect the…

Instrumentation and Detectors · Physics 2013-02-20 Deyang Yu

Dose painting has been developed to modulate the required dose in the target area without increasing the toxicity in healthy areas. Apart from determining the accurate location and size of tumors, quantitative functional imaging can be used…

Medical Physics · Physics 2020-11-24 Yaru Pang , Gary Royle , Spyros Manolopoulos

Medical image segmentation is an increasingly popular area of research in medical imaging processing and analysis. However, many researchers who are new to the field struggle with basic concepts. This tutorial paper aims to provide an…

Image and Video Processing · Electrical Eng. & Systems 2023-04-13 Diedre Carmo , Gustavo Pinheiro , Lívia Rodrigues , Thays Abreu , Roberto Lotufo , Letícia Rittner

In the context of computer models, calibration is the process of estimating unknown simulator parameters from observational data. Calibration is variously referred to as model fitting, parameter estimation/inference, an inverse problem, and…

Methodology · Statistics 2023-10-16 Richard D. Wilkinson , Christopher W. Lanyon

With the continued evolution of modern radiation therapy towards high precision delivery of high therapeutic doses to the tumour while optimally sparing surrounding healthy tissue, imaging becomes a crucial component to identify the…

Medical Physics · Physics 2018-04-24 Katia Parodi

Quantum state tomography (QST) is the gold standard technique for obtaining an estimate for the state of small quantum systems in the laboratory. Its application to systems with more than a few constituents (e.g. particles) soon becomes…

Magnetic Resonance Imaging (MRI) has become one of the most important tools to screen humans in medicine, virtually every modern hospital is equipped with an NMR tomograph. The potential of NMR in 3D imaging tasks is by far greater, but…

Soft Condensed Matter · Physics 2018-09-14 Ralf Stannarius

Recent advancements in model checking have demonstrated significant potential across diverse applications, particularly in signal and image analysis. Medical imaging stands out as a critical domain where model checking can be effectively…

Computer Vision and Pattern Recognition · Computer Science 2025-01-08 Elhoucine Elfatimi , Lahcen El fatimi

Particle therapy is a well established clinical treatment of tumors. More than one hundred particle therapy centers are in operation world wide. The advantage of using hadrons like protons or carbon ions as particles for tumor irradiation…

Brain tumour segmentation is an essential task in medical image processing. Early diagnosis of brain tumours plays a crucial role in improving treatment possibilities and increases the survival rate of the patients. Manual segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2021-11-08 Angad Ripudaman Singh Bajwa

Segmentation, or the outlining of objects within images, is a critical step in the measurement and analysis of cells within microscopy images. While improvements continue to be made in tools that rely on classical methods for segmentation,…

Quantitative Methods · Quantitative Biology 2024-03-15 Nodar Gogoberidze , Beth A. Cimini

Using optical speckle scanning microscopy [1], we demonstrate that clear images of multiple cells can be obtained through biological scattering tissue, with subcellular resolution and good image quality, as long as the size of the imaging…

Optics · Physics 2023-07-19 Xin Yang , Ye Pu , Demetri Psaltis

Medical images constitute a source of information essential for disease diagnosis, treatment and follow-up. In addition, due to its patient-specific nature, imaging information represents a critical component required for advancing…

Computer Vision and Pattern Recognition · Computer Science 2016-06-10 Dorin Comaniciu , Klaus Engel , Bogdan Georgescu , Tommaso Mansi

The partitioning of small molecules in cell membranes---a key parameter for pharmaceutical applications---typically relies on experimentally-available bulk partitioning coefficients. Computer simulations provide a structural resolution of…

Soft Condensed Matter · Physics 2017-12-04 Roberto Menichetti , Kiran H. Kanekal , Kurt Kremer , Tristan Bereau

Quantum state tomography is an integral part of quantum computation and offers the starting point for the validation of various quantum devices. One of the central tasks in the field of state tomography is to reconstruct with high fidelity,…

Quantum Physics · Physics 2022-12-21 Rishabh Gupta , Manas Sajjan , Raphael D. Levine , Sabre Kais

Raman spectroscopy provides spectral information related to the specific molecular structures of substances and has been well established as a powerful tool for studying biological tissues and diagnosing diseases. This article reviews…