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In the present review, we describe three hot topics in cancer research such as circulating tumor cells, exosomes, and 3D environment models. The first section is dedicated to microfluidic platforms for detecting circulating tumor cells,…

Two atmospheric pressure plasma jet devices - a plasma gun and a plasma Tesla jet - are compared in terms of safety and therapeutic efficiency to reduce the tumor volume progression of cholangiocarcinoma, i.e. a rare and very aggressive…

Applied Physics · Physics 2019-11-26 F. Judée , J. Vaquero , S. Guégan , L. Fouassier , T. Dufour

Cancer therapy for deep-seated tumors requires precise irradiation of a small target deep within the patient while minimizing radiation exposure to surrounding tissues. This can be accomplished with a round beam sharply converging towards a…

A compact helicon plasma thruster that features a cusp in its internal magnetic field is analyzed with experiments and simulations. A compensated Langmuir probe and a Faraday cup are used in the former, while a hybrid PIC/fluid transport…

Plasma Physics · Physics 2024-05-14 Pedro Jimenez , Jiewei Zhou , Jaume Navarro , Pablo Fajardo , Mario Merino , Eduardo Ahedo

For the past twelve years, cold plasmas have been positioned as a breakthrough technology for treating cancer thanks to their antitumor properties. The innovation of ad hoc plasma sources and personalized protocols appears crucial to treat…

Medical Physics · Physics 2023-05-23 Henri Decauchy , Allan Pavy , Marine Camus , Laura Fouassier , Thierry Dufour

We present a study of the expansion of an ultracold neutral plasma (UCNP) with an initial density distribution that decays exponentially in space, created by photoionizing atoms shortly after their release from a quadrupole (or biconic…

Plasma Physics · Physics 2022-10-19 MacKenzie K. Warrens , Grant M. Gorman , Stephen J. Bradshaw , Thomas C. Killian

In this study, we conduct a study on magnetic hyperthermia treatment when a vessel is located near the tumor. The holistic framework is established to solve the process of tumor treatment. The interstitial tissue fluid, MNP distribution,…

Malignant brain tumors are among the deadliest neoplasms with the lowest survival rates of any cancer type. In considering surgical tumor resection, suboptimal extent of resection is linked to poor clinical outcomes and lower overall…

Image and Video Processing · Electrical Eng. & Systems 2020-09-23 Benjamin R. Ecclestone , Kevan Bell , Saad Abbasi , Deepak Dinakaran , Frank K. H. van Landeghem , John R. Mackey , Paul Fieguth , Parsin Haji Reza

Micromagnetic beads are widely used in biomedical applications for cell separation, drug delivery, and hypothermia cancer treatment. Here we propose to use self-organized magnetic bead structures which accumulate on fixed magnetic seeding…

Patient derived xenograft (PDX) tumor models initiated in avian chorioallantoic membranes (CAM) are under investigation to evaluate the effectiveness of therapeutic options with the objective of personalizing treatments. CAM PDXs paired…

Atmospheric pressure plasma jets (APPJ) are investigated as an efficient approach to induce antitumor effects of cancerous tissues without inducing any damage (e.g. dessication, burnings). For this, a two-steps methodology has been…

Medical Physics · Physics 2019-12-03 F. Judee , J. Vaquero , L. Fouassier , T. Dufour

Ultracold polar molecules are an ideal platform for studying many-body physics with long-range dipolar interactions. Experiments in this field have progressed enormously, and several groups are pursuing advanced apparatus for manipulation…

Atomic Physics · Physics 2018-04-27 Jacob P. Covey , Luigi De Marco , Oscar L. Acevedo , Ana Maria Rey , Jun Ye

Immunotherapy emerges as promising approach for treating cancer. Encouraging findings have validated the efficacy of immunotherapy medications in addressing tumors, resulting in prolonged survival rates and notable reductions in toxicity…

Image and Video Processing · Electrical Eng. & Systems 2023-07-28 Francesco Rundo , Concetto Spampinato , Michael Rundo

Chip-scale atomic devices built around micro-fabricated alkali vapor cells are at the forefront of compact metrology and atomic sensors. We demonstrate a micro-fabricated vapor cell that is actively-pumped to ultra-high-vacuum (UHV) to…

Experiments have revealed a nontrivial cancer-inhibiting capability of liquid media treated by the plasma jet capable of forming thinly stratified self-organized patterns at a plasma-liquid interface. A pronounced cancer depressing activity…

Medical Physics · Physics 2017-01-09 Zhitong Chen , Shiqiang Zhang , Igor Levchenko , Isak I. Beilis , Michael Keidar

The aim of this study was to investigate the impact of ambient air plasma treatment on both sunflower seed germination and early steps of seedling development under water stress. Dry seeds were exposed to a cold atmospheric plasma (CAP)…

Plasma Physics · Physics 2025-12-30 L. Taras , C. Bailly , T. Dufour

Focused ultrasound stimulated microbubbles have been shown to be capable of inducing blood flow shutdown and necrosis in a range of tissue types in an approach termed antivascular ultrasound or mechanical ablation. In oncology, this…

Medical Physics · Physics 2022-10-17 Xiaoxiao Zhao , Carly Pellow , David E. Goertz

Cold atmospheric pressure plasmas are crucial for applications in medicine, agriculture, and material processing, where their interaction with ambient air generates reactive oxygen and nitrogen species for disinfection and treatment…

Plasma Physics · Physics 2025-03-27 Muhammad Rizwan Akram , Abbas Semnani

In the field of biomedicine magnetic beads are used for drug delivery and to treat hyperthermia. Here we propose to use self-organized bead structures to isolate circulating tumor cells using lab-on-chip technologies. Typically blood flows…