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We report that population dynamics in fluctuating environment accompanies mathematically equivalent structure to steady state thermodynamics. By employing the structure, population growth in fluctuating environment is decomposed into…

Statistical Mechanics · Physics 2016-03-04 Yuki Sughiyama , Tetsuya J. Kobayashi

The question of the local stability of the (replica-symmetric) amorphous solid state is addressed for a class of systems undergoing a continuous liquid to amorphous-solid phase transition driven by the effect of random constraints. The…

Disordered Systems and Neural Networks · Physics 2009-10-31 Horacio E. Castillo , Paul M. Goldbart , Annette Zippelius

Topological defects are increasingly being identified in various biological systems, where their characteristic flow fields and stress patterns are associated with continuous active stress generation by biological entities. Here, using…

Soft Condensed Matter · Physics 2022-11-09 Lasse Bonn , Aleksandra Ardaseva , Romain Mueller , Tyler N. Shendruk , Amin Doostmohammadi

Plasmoid-driven magnetic reconnection in elongated current sheets is suspected to be an ubiquitous phenomenon in space and astrophysical plasmas, but the mechanisms driving its onset and dynamics are still debated. Deciphering the physical…

A ubiquitous feature of living cells is their growth over time followed by division into daughter cells. How isogenic cell populations maintain size homeostasis, i.e., a narrow distribution of cell size, is an intriguing fundamental…

Cell Behavior · Quantitative Biology 2016-06-03 César Augusto Vargas-García , Mohammad Soltani , Abhyudai Singh

During growth, tissue expands and deforms. Given its elastic properties, stresses emerge in an expanding and deforming tissue. Cell rearrangements can dissipate these stresses and numerous experiments confirm the viscoelastic properties of…

Tissues and Organs · Quantitative Biology 2017-10-20 M. D. Peters , D. Iber

Engineering synthetic materials that mimic the remarkable complexity of living organisms is a fundamental challenge in science and technology. We study the spatiotemporal patterns that emerge when an active nematicfilm of microtubules and…

The collective chemotaxis of multicellular clusters is an important phenomenon in various physiological contexts, ranging from embryonic development to cancer metastasis. Such clusters often display interesting shape dynamics and…

Tissues and Organs · Quantitative Biology 2025-06-03 Monika Sanoria , Gema Malet-Engra , Giorgio Scita , Nir Gov , Ajay Gopinathan

External stress can accelerate molecular mobility of amorphous solids by several orders of magnitude. The changes in mobility are commonly interpreted through the Eyring model, which invokes an empirical activation volume whose origin…

Soft Condensed Matter · Physics 2022-03-14 Entao Yang , Robert A. Riggleman

Here we study a driven lattice gas model for microtubule depolymerizing molecular motors, where traffic jams of motors induce stochastic switching between microtubule growth and shrinkage. We term this phenomenon \enquote{traffic dynamic…

Statistical Mechanics · Physics 2015-05-07 Louis Reese , Anna Melbinger , Erwin Frey

The distribution of local residual stresses (threshold to instability) that controls the statistical properties of plastic flow in athermal amorphous solids is examined with an atomistic simulation technique. For quiescent configurations,…

Disordered Systems and Neural Networks · Physics 2020-07-02 Céline Ruscher , Jörg Rottler

Using longitudinal study data, we dynamically model how aging affects homeostasis in both mice and humans. We operationalize homeostasis as a multivariate mean-reverting stochastic process. We hypothesize that biomarkers have stable…

Other Quantitative Biology · Quantitative Biology 2023-12-14 Glen Pridham , Andrew D. Rutenberg

To produce sounds, we adjust the tension of our vocal folds to shape their properties and control the pitch. This efficient mechanism offers inspiration for designing reconfigurable materials and adaptable soft robots. However,…

Soft Condensed Matter · Physics 2025-06-18 Alexandre Delory , Daniel A. Kiefer , Maxime Lanoy , Antonin Eddi , Claire Prada , Fabrice Lemoult

We analyze the force-extension curve for a general class of systems, which are described at the mesoscopic level by a free energy depending on the extension of its components. Similarly to what is done in real experiments, the total length…

Biological Physics · Physics 2014-07-17 A. Prados , A. Carpio , L. L. Bonilla

Although riparian vegetation is present in or along many water courses of the world, its active role resulting from the interaction with flow and sediment processes has only recently become an active field of research. Especially, the role…

Fluid Dynamics · Physics 2014-11-10 Fabian Bärenbold , Benoît Crouzy , Paolo Perona

In sustained growth with random dynamics stationary distributions can exist without detailed balance. This suggests thermodynamical behavior in fast growing complex systems. In order to model such phenomena we apply both a discrete and a…

Statistical Mechanics · Physics 2017-03-22 Tamás Biró , Zoltán Néda

In this work, we have explored growth-induced mechanical instability in an isotropic circular hyperelastic plate. Consistent two-dimensional governing equations for a plate under a general finite strain are derived using a variational…

Pattern Formation and Solitons · Physics 2021-03-12 Sumit Mehta , Gangadharan Raju , Prashant Saxena

Active processes drive and guide biological dynamics across scales -- from subcellular cytoskeletal remodelling, through tissue development in embryogenesis, to population-level bacterial colonies expansion. In each of these, biological…

Physical experiments can characterize the elastic response of granular materials in terms of macroscopic state-variables, namely volume (packing) fraction and stress, while the microstructure is not accessible and thus neglected. Here, by…

Soft Condensed Matter · Physics 2015-06-16 Nishant Kumar , Stefan Luding , Vanessa Magnanimo

Active stresses in biological cells and tissues drive many developmental processes. However, increasing experimental evidence suggests that additional mechanical interactions with surrounding material can play a crucial role in guiding…

Soft Condensed Matter · Physics 2026-03-10 Douglas MacMyn Brown , Alexander Mietke