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Segmentation of Multiple Sclerosis (MS) lesions is a challenging problem. Several deep-learning-based methods have been proposed in recent years. However, most methods tend to be static, that is, a single model trained on a large,…
The diagnosis of early stages of Alzheimer's disease (AD) is essential for timely treatment to slow further deterioration. Visualizing the morphological features for the early stages of AD is of great clinical value. In this work, a novel…
Unsupervised learning can discover various unseen abnormalities, relying on large-scale unannotated medical images of healthy subjects. Towards this, unsupervised methods reconstruct a 2D/3D single medical image to detect outliers either in…
Objective: Identifying disability-related brain changes is important for multiple sclerosis (MS) patients. Currently, there is no clear understanding about which pathological features drive disability in single MS patients. In this work, we…
Acquiring images of the same anatomy with multiple different contrasts increases the diversity of diagnostic information available in an MR exam. Yet, scan time limitations may prohibit acquisition of certain contrasts, and images for some…
Computed tomography (CT) is a popular medical imaging modality in clinical applications. At the same time, the x-ray radiation dose associated with CT scans raises public concerns due to its potential risks to the patients. Over the past…
Fast Magnetic Resonance Imaging (MRI) is highly in demand for many clinical applications in order to reduce the scanning cost and improve the patient experience. This can also potentially increase the image quality by reducing the motion…
Magnetic resonance imaging (MRI) is central to the diagnosis of multiple sclerosis, where the identification of biomarkers such as the central vein sign benefits from high-resolution images. However, most clinical brain MRI scans are…
Background: Several studies indicate that the anterior visual pathway provides information about the dynamics of axonal degeneration in Multiple Sclerosis (MS). Current research in the field is focused on the quest for the most…
State-of-the-art methods for retinal vessel segmentation mainly rely on manually labeled vessels as the ground truth for supervised training. The quality of manual labels plays an essential role in the segmentation accuracy, while in…
Complete and high-quality multi-modal Magnetic Resonance Imaging (MRI) is essential for accurate neuro-oncological assessment, as each contrast provides complementary anatomical and pathological information. However, acquiring all…
Numerous factors could lead to partial deteriorations of medical images. For example, metallic implants will lead to localized perturbations in MRI scans. This will affect further post-processing tasks such as attenuation correction in…
The accurate diagnosis and molecular profiling of colorectal cancers are critical for planning the best treatment options for patients. Microsatellite instability (MSI) or mismatch repair (MMR) status plays a vital role in appropriate…
Recovering the T2 distribution from multi-echo T2 magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this…
Attenuation correction is an essential requirement of positron emission tomography (PET) image reconstruction to allow for accurate quantification. However, attenuation correction is particularly challenging for PET-MRI as neither PET nor…
Morphological and diagnostic evaluation of pediatric musculoskeletal system is crucial in clinical practice. However, most segmentation models do not perform well on scarce pediatric imaging data. We propose a new pre-trained regularized…
Compared to traditional methods, Deep Learning (DL) becomes a key technology for computer vision tasks. Synthetic data generation is an interesting use case for DL, especially in the field of medical imaging such as Magnetic Resonance…
Multiparametric magnetic resonance imaging (mp-MRI) has shown excellent results in the detection of prostate cancer (PCa). However, characterizing prostate lesions aggressiveness in mp-MRI sequences is impossible in clinical practice, and…
White matter hyperintensities (WMH) are bright regions on T2-weighted magnetic resonance imaging (MRI) scans and are associated with cerebrovascular pathology and neurodegeneration, including myelin loss. While Luxol Fast Blue…
[18F]-florbetaben positron emission tomography (PET) imaging is an established marker of {\ss}-Amyloid (A{\ss}) that is being increasingly used to assess A{\ss} deposition in AD. This study presents a novel, explainable machine…