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Recent studies suggest that combined analysis of Magnetic resonance imaging~(MRI) that measures brain atrophy and positron emission tomography~(PET) that quantifies hypo-metabolism provides improved accuracy in diagnosing Alzheimer's…
For effective treatment of Alzheimer disease (AD), it is important to identify subjects who are most likely to exhibit rapid cognitive decline. Herein, we developed a novel framework based on a deep convolutional neural network which can…
Recent attempts at Super-Resolution for medical images used deep learning techniques such as Generative Adversarial Networks (GANs) to achieve perceptually realistic single image Super-Resolution. Yet, they are constrained by their…
The spinal cord is frequently affected by atrophy and/or lesions in multiple sclerosis (MS) patients. Segmentation of the spinal cord and lesions from MRI data provides measures of damage, which are key criteria for the diagnosis,…
Automated segmentation of multiple sclerosis (MS) lesions using multicontrast magnetic resonance (MR) images improves efficiency and reproducibility compared to manual delineation, with deep learning (DL) methods achieving state-of-the-art…
Positron Emission Tomography and Magnetic Resonance Imaging (PET-MRI) systems can obtain functional and anatomical scans. PET suffers from a low signal-to-noise ratio. Meanwhile, the k-space data acquisition process in MRI is…
In clinical medicine, magnetic resonance imaging (MRI) is one of the most important tools for diagnosis, triage, prognosis, and treatment planning. However, MRI suffers from an inherent slow data acquisition process because data is…
Optical coherence tomography (OCT) is one of the non-invasive and easy-to-acquire biomarkers (the thickness of the retinal layers, which is detectable within OCT scans) being investigated to diagnose Alzheimer's disease (AD). This work aims…
The diagnosis, prognosis, and treatment of patients with musculoskeletal (MSK) disorders require radiology imaging (using computed tomography, magnetic resonance imaging(MRI), and ultrasound) and their precise analysis by expert…
Multiple Sclerosis is a degenerative condition of the central nervous system that affects nearly 2.5 million of individuals in terms of their physical, cognitive, psychological and social capabilities. Researchers are currently…
Segmentation of magnetic resonance (MR) images is a fundamental step in many medical imaging-based applications. The recent implementation of deep convolutional neural networks (CNNs) in image processing has been shown to have significant…
Medical image super-resolution (MedSR) is essential for improving diagnostic precision across diverse imaging modalities such as MRI, CT, X-ray, Ultrasound, and Fundus imaging. Despite rapid advances in deep learning, challenges remain in…
Multiple imaging modalities are often used for disease diagnosis, prediction, or population-based analyses. However, not all modalities might be available due to cost, different study designs, or changes in imaging technology. If the…
Magnetic Resonance Angiography (MRA) has become an essential MR contrast for imaging and evaluation of vascular anatomy and related diseases. MRA acquisitions are typically ordered for vascular interventions, whereas in typical scenarios,…
Large high-quality medical image datasets are difficult to acquire but necessary for many deep learning applications. For positron emission tomography (PET), reconstructed image quality is limited by inherent Poisson noise. We propose a…
This study investigates the application of surface-enhanced Raman spectroscopy (SERS) as a diagnostic tool for myasthenia gravis, a severe neuromuscular disorder characterized by muscle weakness and fatigue. Blood serum samples were…
In medical image synthesis, model training could be challenging due to the inconsistencies between images of different modalities even with the same patient, typically caused by internal status/tissue changes as different modalities are…
Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by the death of dopaminergic neurons, leading to various movement disorder symptoms. Early diagnosis of PD is crucial to prevent adverse effects, yet…
Structure-preserved denoising of 3D magnetic resonance imaging (MRI) images is a critical step in medical image analysis. Over the past few years, many algorithms with impressive performances have been proposed. In this paper, inspired by…
$\textbf{Purpose}$: Automatic quantification of longitudinal changes in PET scans for lymphoma patients has proven challenging, as residual disease in interim-therapy scans is often subtle and difficult to detect. Our goal was to develop a…