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This paper categorizes the parameterized complexity of the algorithmic problems Perfect Phylogeny and Triangulating Colored Graphs when parameterized by the number of genes and colors, respectively. We show that they are complete for the…

Computational Complexity · Computer Science 2023-11-28 Jorke M. de Vlas

Perfect sorting by reversals, a problem originating in computational genomics, is the process of sorting a signed permutation to either the identity or to the reversed identity permutation, by a sequence of reversals that do not break any…

Discrete Mathematics · Computer Science 2012-01-05 Mathilde Bouvel , Cedric Chauve , Marni Mishna , Dominique Rossin

Algorithms to find optimal alignments among strings, or to find a parsimonious summary of a collection of strings, are well studied in a variety of contexts, addressing a wide range of interesting applications. In this paper, we consider…

Social and Information Networks · Computer Science 2020-11-09 Patty Commins , David Liben-Nowell , Tina Liu , Kiran Tomlinson

Likelihood-based methods are widely considered the best approaches for reconstructing ancestral states. Although much effort has been made to study properties of these methods, previous works often assume that both the tree topology and…

Methodology · Statistics 2021-04-02 Lam Si Tung Ho , Edward Susko

Predicting horizontal gene transfers often requires comparative sequence data, but recent work has shown that character-based approaches could also be useful for this task. Notably, perfect transfer networks (PTN) explain the character…

Discrete Mathematics · Computer Science 2025-06-17 Alitzel López Sánchez , Manuel Lafond

To the known fact that Parsimony method sometimes fails on the problem of inferring species trees from gene trees, here we proved that no mater of what topology the true 9-taxon and greater species tree is the only thing one needs to break…

Populations and Evolution · Quantitative Biology 2019-08-13 Vikenty Mikheev , Serge E. Miheev

We apply the theory of markov random fields on trees to derive a phase transition in the number of samples needed in order to reconstruct phylogenies. We consider the Cavender-Farris-Neyman model of evolution on trees, where all the inner…

Probability · Mathematics 2007-05-23 Elchanan Mossel

Phylogenetic trees canonically arise as embeddings of phylogenetic networks. We recently showed that the problem of deciding if two phylogenetic networks embed the same sets of phylogenetic trees is computationally hard, \blue{in…

Combinatorics · Mathematics 2021-04-13 Janosch Doecker , Simone Linz , Charles Semple

Motivation: Many inference tools use the Perfect Phylogeny Model (PPM) to learn trees from noisy variant allele frequency (VAF) data. Learning in this setting is hard, and existing tools use approximate or heuristic algorithms. An…

Quantitative Methods · Quantitative Biology 2019-08-26 Surjyendu Ray , Bei Jia , Sam Safavi , Tim van Opijnen , Ralph Isberg , Jason Rosch , José Bento

Several algorithms build on the perfect phylogeny model to infer evolutionary trees. This problem is particularly hard when evolutionary trees are inferred from the fraction of genomes that have mutations in different positions, across…

Data Structures and Algorithms · Computer Science 2018-12-31 Bei Jia , Surjyendu Ray , Sam Safavi , José Bento

Phylogenetic comparative methods (PCMs) are widely used to study trait evolution. However, many evolutionary histories involve reticulate evolutionary scenarios, such as hybridization, that violate core assumptions of these methods. In this…

Populations and Evolution · Quantitative Biology 2026-03-30 Lydia Morley , Emma Lehmberg , Sungsik Kong

A normal (phylogenetic) network with $k$ reticulations displays $2^k$ phylogenetic trees. In this paper, we establish an analogous result for tree-child (phylogenetic) networks with no underlying $3$-cycles. In particular, we show that a…

Combinatorics · Mathematics 2025-08-20 Charles Semple , Kristina Wicke

We study the natural problem of Triplet Reconstruction (also Rooted Triplets Consistency or Triplet Clustering), originally motivated in computational biology and relational databases (Aho, Sagiv, Szymanski, and Ullman, 1981): given $n$…

Data Structures and Algorithms · Computer Science 2023-04-06 Vaggos Chatziafratis , Konstantin Makarychev

More than ever, today we are left with the abundance of molecular data outpaced by the advancements of the phylogenomic methods. Especially in the case of presence of many genes over a set of species under the phylogeny question, more…

Applications · Statistics 2021-11-29 Ali Amiryousefi

Recently, the minimum number of reticulation events that is required to simultaneously embed a collection P of rooted binary phylogenetic trees into a so-called temporal network has been characterized in terms of cherry-picking sequences.…

Populations and Evolution · Quantitative Biology 2021-04-13 Janosch Döcker , Simone Linz

Given $n$ men, $n$ women, and $n$ dogs, we assume that each man has a complete preference list of women, while each woman does a complete preference list of dogs, and each dog does a complete preference list of men. We study the so-called…

Combinatorics · Mathematics 2022-02-01 E. Yu Lerner

We resolve a long-standing open question, about the existence of a constant-factor approximation algorithm for the average-case \textsc{Decision Tree} problem with uniform probability distribution over the hypotheses. We answer the question…

Data Structures and Algorithms · Computer Science 2026-04-29 Michał Szyfelbein

Given a pattern string $P$ of length $n$ and a query string $T$ of length $m$, where the characters of $P$ and $T$ are drawn from an alphabet of size $\Delta$, the {\em exact string matching} problem consists of finding all occurrences of…

Data Structures and Algorithms · Computer Science 2015-10-01 Srikrishnan Divakaran

A coloring of a tree is convex if the vertices that pertain to any color induce a connected subtree; a partial coloring (which assigns colors to some of the vertices) is convex if it can be completed to a convex (total) coloring. Convex…

Data Structures and Algorithms · Computer Science 2007-05-23 Shlomo Moran , Sagi Snir

We show that there exists a constant $c>0$ such that every $n$-vertex tree $T$ with $\Delta(T)\le cn$ has Ramsey number $R(T)=\max\{t_1+2t_2,2t_1\}-1$, where $t_1\ge t_2$ are the sizes of the bipartition classes of $T$. This improves an…

Combinatorics · Mathematics 2025-09-10 Richard Montgomery , Matías Pavez-Signé , Jun Yan
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