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Random Boolean networks, originally invented as models of genetic regulatory networks, are simple models for a broad class of complex systems that show rich dynamical structures. From a biological perspective, the most interesting networks…

Disordered Systems and Neural Networks · Physics 2009-11-07 Joshua E. S. Socolar , Stuart A. Kauffman

In this paper we show how to formulate and solve disturbance decoupling problems over networks while choosing a minimal number of input and output nodes. Feedback laws that isolate and eliminate the impact of disturbance nodes on specific…

Optimization and Control · Mathematics 2026-03-17 Luca Claude Gino Lebon , Claudio Altafini

Probabilistic Boolean networks (PBNs) is an important mathematical framework widely used for modelling and analysing biological systems. PBNs are suited for modelling large biological systems, which more and more often arise in systems…

Computational Engineering, Finance, and Science · Computer Science 2016-05-04 Andrzej Mizera , Jun Pang , Qixia Yuan

In the applications of Boolean networks to modeling biological systems, an important computational problem is the detection of the fixed points of these networks. This is an NP-complete problem in general. There have been various attempts…

Quantitative Methods · Quantitative Biology 2014-04-23 Yi Ming Zou

In this work, we explore the state-space formulation of a network process to recover, from partial observations, the underlying network topology that drives its dynamics. To do so, we employ subspace techniques borrowed from system…

Signal Processing · Electrical Eng. & Systems 2019-06-26 Mario Coutino , Elvin Isufi , Takanori Maehara , Geert Leus

We construct and investigate Boolean networks that follow a given reliable trajectory in state space, which is insensitive to fluctuations in the updating schedule, and which is also robust against noise. Robustness is quantified as the…

Biological Physics · Physics 2010-12-02 Christoph Schmal , Tiago P. Peixoto , Barbara Drossel

A logical function can be used to characterizing a property of a state of Boolean network (BN), which is considered as an aggregation of states. To illustrate the dynamics of a set of logical functions, which characterize our concerned…

Systems and Control · Electrical Eng. & Systems 2021-04-20 Daizhan Cheng , Lijun Zhang , Dongyao Bi

Random Boolean networks are models of disordered causal systems that can occur in cells and the biosphere. These are open thermodynamic systems exhibiting a flow of energy that is dissipated at a finite rate. Life does work to acquire more…

Other Quantitative Biology · Quantitative Biology 2010-09-16 Hilary A. Carteret , Kelly John Rose , Stuart A. Kauffman

In this paper, we study the distributed control of networked cyber-physical systems when a much more energy-efficient distributed communication management strategy is proposed to solve the well-studied consensus problem. In contrast to the…

Systems and Control · Computer Science 2016-09-14 Yongcan Cao , Eduardo Pasiliao

We investigate how elimination of variables can affect the asymptotic dynamics and phenotype control of Boolean networks. In particular, we look at the impact on minimal trap spaces, and identify a structural condition that guarantees their…

Discrete Mathematics · Computer Science 2024-08-14 Elisa Tonello , Loïc Paulevé

A useful approach to the mathematical analysis of large-scale biological networks is based upon their decompositions into monotone dynamical systems. This paper deals with two computational problems associated to finding decompositions…

Molecular Networks · Quantitative Biology 2007-05-23 Bhaskar DasGupta , German Andres Enciso , Eduardo Sontag , Yi Zhang

We present and discuss the results of an experimental analysis in the design of Boolean networks by means of genetic algorithms. A population of networks is evolved with the aim of finding a network such that the attractor it reaches is of…

Neural and Evolutionary Computing · Computer Science 2011-02-01 Andrea Roli , Cristian Arcaroli , Marco Lazzarini , Stefano Benedettini

In this paper, we focus on the study of quotients of Boolean control networks (BCNs) with the motivation that they might serve as smaller models that still carry enough information about the original network. Given a BCN and an equivalence…

Optimization and Control · Mathematics 2020-07-13 Rui Li , Qi Zhang , Tianguang Chu

A state feedback control strategy is proposed for input-output (IO) decoupling of a class of fully output controllable Boolean control networks (BCNs). Some necessary and sufficient conditions for BCN IO-decoupling are presented. As an…

Systems and Control · Electrical Eng. & Systems 2023-10-05 Yiliang Li , Hongli Lyu , Jun-e Feng , Abdelhamid Tayebi

Previous work in Boolean dynamical networks has suggested that the number of components that must be controlled to select an existing attractor is typically set by the number of attractors admitted by the dynamics, with no dependence on the…

Molecular Networks · Quantitative Biology 2024-10-11 Bryan C. Daniels , Enrico Borriello

Random boolean networks are a model of genetic regulatory networks that has proven able to describe experimental data in biology. They not only reproduce important phenomena in cell dynamics, but they are also extremely interesting from a…

Dynamical Systems · Mathematics 2015-02-26 Marco Villani , Davide Campioli , Chiara Damiani , Andrea Roli , Alessandro Filisetti , Roberto Serra

Controllability of complex networks arises in many technological problems involving social, financial, road, communication, and smart grid networks. In many practical situations, the underlying topology might change randomly with time, due…

Systems and Control · Computer Science 2020-01-08 Fernando Gama , Elvin Isufi , Alejandro Ribeiro , Geert Leus

This paper (parts I and II) provides an expository introduction to monotone and near-monotone dynamical systems associated to biochemical networks, those whose graphs are consistent or near-consistent. Many conclusions can be drawn from…

Molecular Networks · Quantitative Biology 2007-05-23 Eduardo D. Sontag

This paper deals with controllability of dynamical networks. It is often unfeasible or unnecessary to fully control large-scale networks, which motivates the control of a prescribed subset of agents of the network. This specific form of…

Optimization and Control · Mathematics 2016-08-09 Henk J. van Waarde , M. Kanat Camlibel , Harry L. Trentelman

In this Letter we propose a method to control a set of arbitrary nodes in a directed network such that they follow a synchronous trajectory which is, in general, not shared by the other units of the network. The problem is inspired to those…

Chaotic Dynamics · Physics 2021-01-19 Bruno Ursino , Lucia Valentina Gambuzza , Vito Latora , Mattia Frasca