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The accurate classification of lymphoma subtypes using hematoxylin and eosin (H&E)-stained tissue is complicated by the wide range of morphological features these cancers can exhibit. We present LymphoML - an interpretable machine learning…

The task of labeling data for training deep neural networks is daunting and tedious, requiring millions of labels to achieve the current state-of-the-art results. Such reliance on large amounts of labeled data can be relaxed by exploiting…

Machine Learning · Computer Science 2016-02-17 Aysegul Dundar , Jonghoon Jin , Eugenio Culurciello

PURPOSE: Deep learning methods for classifying prostate cancer (PCa) in ultrasound images typically employ convolutional networks (CNNs) to detect cancer in small regions of interest (ROI) along a needle trace region. However, this approach…

The application of supervised deep learning methods in digital pathology is limited due to their sensitivity to domain shift. Digital Pathology is an area prone to high variability due to many sources, including the common practice of…

Image and Video Processing · Electrical Eng. & Systems 2020-12-24 Jelica Vasiljević , Friedrich Feuerhake , Cédric Wemmert , Thomas Lampert

The development of reliable imaging biomarkers for the analysis of colorectal cancer (CRC) in hematoxylin and eosin (H&E) stained histopathology images requires an accurate and reproducible classification of the main tissue components in…

Pathologists find tedious to examine the status of the sentinel lymph node on a large number of pathological scans. The examination process of such lymph node which encompasses metastasized cancer cells is histopathologically organized.…

Computer Vision and Pattern Recognition · Computer Science 2019-06-25 Amit Kumar Jaiswal , Ivan Panshin , Dimitrij Shulkin , Nagender Aneja , Samuel Abramov

Monitoring plankton populations in situ is fundamental to preserve the aquatic ecosystem. Plankton microorganisms are in fact susceptible of minor environmental perturbations, that can reflect into consequent morphological and dynamical…

Computer Vision and Pattern Recognition · Computer Science 2022-09-15 Paolo Didier Alfano , Marco Rando , Marco Letizia , Francesca Odone , Lorenzo Rosasco , Vito Paolo Pastore

Unsupervised learning has been widely applied to various tasks in particle physics. However, existing models lack precise control over their learned representations, limiting physical interpretability and hindering their use for accurate…

High Energy Physics - Experiment · Physics 2025-12-01 Xing-Jian Lv , De-Xing Miao , Zi-Jun Xu , Jian-Chun Wang

Clinical decision support for histopathology image data mainly focuses on strongly supervised annotations, which offers intuitive interpretability, but is bound by expert performance. Here, we propose an explainable cancer relapse…

Computer Vision and Pattern Recognition · Computer Science 2021-11-29 Esther Dietrich , Patrick Fuhlert , Anne Ernst , Guido Sauter , Maximilian Lennartz , H. Siegfried Stiehl , Marina Zimmermann , Stefan Bonn

Supervised Learning has been successfully used to produce phase diagrams and identify phase boundaries when local order parameters are unavailable. Here, we apply unsupervised learning to this task. By using readily available clustering…

Strongly Correlated Electrons · Physics 2019-08-19 Steven Durr , Sudip Chakravarty

Exemplar-based methods rely on informative data points or prototypes to guide the optimization of learning algorithms. Such data facilitate interpretable model design and prediction. Of particular interest is the utility of exemplars in…

Machine Learning · Computer Science 2022-11-22 Priya Mani , Carlotta Domeniconi

Cancer is a number of related yet highly heterogeneous diseases. Correct identification of cancer subtypes is critical for clinical decisions. The advance in sequencing technologies has made it possible to study cancer based on abundant…

Applications · Statistics 2018-11-27 Xiaochun Chen , Honggang Wang , Donghui Yan

Although deep neural networks (DNNs) have shown impressive performance on many perceptual tasks, they are vulnerable to adversarial examples that are generated by adding slight but maliciously crafted perturbations to benign images.…

Machine Learning · Computer Science 2022-10-18 Hui Liu , Bo Zhao , Kehuan Zhang , Peng Liu

Prostate cancer is a disease which poses an interesting clinical question: should it be treated? A small subset of prostate cancers are aggressive and require removal and treatment to prevent metastatic spread. However, conventional…

Quantitative Methods · Quantitative Biology 2024-03-14 Daniel West , Susan Stepney , Y. Hancock

In this work we used unsupervised machine learning methods in order to find possible clustering structures in superconducting materials data sets. We used the SuperCon database, as well as our own data sets complied from literature, in…

Superconductivity · Physics 2022-07-13 B. Roter , N. Ninkovic , S. V. Dordevic

Gene expression profiles have been widely used to characterize patterns of cellular responses to diseases. As data becomes available, scalable learning toolkits become essential to processing large datasets using deep learning models to…

Machine Learning · Computer Science 2019-02-01 Ya Ju Fan , Jonathan E. Allen , Sam Ade Jacobs , Brian C. Van Essen

Prostate cancer is one of the most prevalent malignancies in the world. While deep learning has potential to further improve computer-aided prostate cancer detection on MRI, its efficacy hinges on the exhaustive curation of manually…

Computer Vision and Pattern Recognition · Computer Science 2024-06-19 Alex Chen , Nathan Lay , Stephanie Harmon , Kutsev Ozyoruk , Enis Yilmaz , Brad J. Wood , Peter A. Pinto , Peter L. Choyke , Baris Turkbey

In this paper we propose a reinforcement learning based weakly supervised system for localisation. We train a controller function to localise regions of interest within an image by introducing a novel reward definition that utilises…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Martynas Pocius , Wen Yan , Dean C. Barratt , Mark Emberton , Matthew J. Clarkson , Yipeng Hu , Shaheer U. Saeed

The automatic classification of radar waveform is a fundamental technique in electronic countermeasures (ECM).Recent supervised deep learning-based methods have achieved great success in a such classification task.However, those methods…

Signal Processing · Electrical Eng. & Systems 2022-10-14 HanCong Feng , XinHai Yan , KaiLi Jiang , XinYu Zhao , Bin Tang

In visual recognition tasks, such as image classification, unsupervised learning exploits cheap unlabeled data and can help to solve these tasks more efficiently. We show that the recursive autoconvolution operator, adopted from physics,…

Computer Vision and Pattern Recognition · Computer Science 2017-03-28 Boris Knyazev , Erhardt Barth , Thomas Martinetz
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