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Estimating intra- and extra-axonal microstructure parameters, such as volume fractions and diffusivities, has been one of the major efforts in brain microstructure imaging with MRI. The Standard Model (SM) of diffusion in white matter has…

Diffusion models have demonstrated powerful performance in generating high-quality images. A typical example is text-to-image generator like Stable Diffusion. However, their widespread use also poses potential privacy risks. A key concern…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Guo Li , Weihong Chen , Yongfu Fan

The white matter of the brain is organised into axonal bundles that support long-range neural communication. Although diffusion MRI (dMRI) enables detailed mapping of these pathways through tractography, how white matter pathways directly…

Neurons and Cognition · Quantitative Biology 2026-02-24 Yifei Sun , James M. Shine , Robert D. Sanders , Robin F. H. Cash , Sharon L. Naismith , Fernando Calamante , Jinglei Lv

We propose a data-driven framework to learn interaction kernels in stochastic multi-agent systems. Our approach aims at identifying the functional form of nonlocal interaction and diffusion terms directly from trajectory data, without any a…

Machine Learning · Computer Science 2026-03-18 Giacomo Albi , Alessandro Alla , Elisa Calzola

We propose Fiber Bundle Networks (FiberNet), a novel machine learning framework integrating differential geometry with machine learning. Unlike traditional deep neural networks relying on black-box function fitting, we reformulate…

Machine Learning · Computer Science 2025-12-02 Dong Liu

We present StreamNet, an autoencoder architecture for the analysis of the highly heterogeneous geometry of large collections of white matter streamlines. This proposed framework takes advantage of geometry-preserving properties of the…

Quantitative Methods · Quantitative Biology 2022-10-20 Andrew Lizarraga , Katherine L. Narr , Kirsten A. Donald , Shantanu H. Joshi

The individual course of white matter fiber tracts is an important key for analysis of white matter characteristics in healthy and diseased brains. Uniquely, diffusion-weighted MRI tractography in combination with region-based or…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Jakob Wasserthal , Peter Neher , Klaus H. Maier-Hein

Diffusion MRI (dMRI) tractography enables in vivo mapping of brain structural connections, but traditional connectome generation is time-consuming and requires gray matter parcellation, posing challenges for large-scale studies. We…

Image and Video Processing · Electrical Eng. & Systems 2025-06-12 Marcus J. Vroemen , Yuqian Chen , Yui Lo , Tengfei Xue , Weidong Cai , Fan Zhang , Josien P. W. Pluim , Lauren J. O'Donnell

Diffusion MRI (dMRI) streamline tractography, the gold standard for in vivo estimation of brain white matter (WM) pathways, has long been considered indicative of macroscopic relationships with WM microstructure. However, recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Tian Yu , Yunhe Li , Michael E. Kim , Chenyu Gao , Qi Yang , Leon Y. Cai , Susane M. Resnick , Lori L. Beason-Held , Daniel C. Moyer , Kurt G. Schilling , Bennett A. Landman

Shape plays an important role in computer graphics, offering informative features to convey an object's morphology and functionality. Shape analysis in brain imaging can help interpret structural and functionality correlations of the human…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Yui Lo , Yuqian Chen , Dongnan Liu , Wan Liu , Leo Zekelman , Fan Zhang , Yogesh Rathi , Nikos Makris , Alexandra J. Golby , Weidong Cai , Lauren J. O'Donnell

Multi-modality image fusion aims to synthesize a single, comprehensive image from multiple source inputs. Traditional approaches, such as CNNs and GANs, offer efficiency but struggle to handle low-quality or complex inputs. Recent advances…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Ran Zhang , Xuanhua He , Ke Cao , Liu Liu , Li Zhang , Man Zhou , Jie Zhang

White matter structures composed of myelinated axons in the living human brain are primarily studied by diffusion-weighted MRI (dMRI). These long-range projections are typically characterized in a two-step process: dMRI is used to estimate…

Neurons and Cognition · Quantitative Biology 2017-10-09 Matthew Cieslak , Tegan Brennan , Wendy Meiring , Lukas J. Volz , Clint Greene , Alexander Asturias , Subhash Suri , Scott T. Grafton

Internal features from large-scale pre-trained diffusion models have recently been established as powerful semantic descriptors for a wide range of downstream tasks. Works that use these features generally need to add noise to images before…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Nick Stracke , Stefan Andreas Baumann , Kolja Bauer , Frank Fundel , Björn Ommer

Remote sensing semantic segmentation must address both what the ground objects are within an image and where they are located. Consequently, segmentation models must ensure not only the semantic correctness of large-scale patches…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Hao Wang , Keyan Hu , Xin Guo , Haifeng Li , Chao Tao

This article proposes diffusion LMS strategies for distributed estimation over adaptive networks that are able to exploit sparsity in the underlying system model. The approach relies on convex regularization, common in compressive sensing,…

Machine Learning · Computer Science 2015-06-05 Paolo Di Lorenzo , Ali H. Sayed

Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections at macro scale. Over the last two decades, the study of brain connectivity using…

Quantitative Methods · Quantitative Biology 2021-04-26 Fan Zhang , Alessandro Daducci , Yong He , Simona Schiavi , Caio Seguin , Robert Smith , Chun-Hung Yeh , Tengda Zhao , Lauren J. O'Donnell

A different route to identification of time-invariant linear systems has been recently proposed which does not require committing to a specific parametric model structure. Impulse responses are described in a nonparametric Bayesian…

Systems and Control · Electrical Eng. & Systems 2020-05-15 Gianluigi Pillonetto , Alessandro Chiuso , Giuseppe De Nicolao

White matter hyperintensities (WMH) are radiological markers of small vessel disease and neurodegeneration, whose accurate segmentation and spatial localization are crucial for diagnosis and monitoring. While multimodal MRI offers…

Image and Video Processing · Electrical Eng. & Systems 2025-06-30 Julia Machnio , Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

With the growing interest in foundation models for brain signals, graph-based pretraining has emerged as a promising paradigm for learning transferable representations from connectome data. However, existing contrastive and masked…

Machine Learning · Computer Science 2026-03-10 Xinxu Wei , Rong Zhou , Lifang He , Yu Zhang

Diffusion weighted MRI (dMRI) provides a non invasive virtual reconstruction of the brain's white matter structures through tractography. Analyzing dMRI measures along the trajectory of white matter bundles can provide a more specific…

Quantitative Methods · Quantitative Biology 2019-06-21 Samuel St-Jean , Maxime Chamberland , Max A. Viergever , Alexander Leemans