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Deep learning approaches for diffusion MRI have so far focused primarily on voxel-based segmentation of lesions or white-matter fiber tracts. A drawback of representing tracts as volumetric labels, rather than sets of streamlines, is that…

Image and Video Processing · Electrical Eng. & Systems 2020-09-10 Christian Ewert , David Kügler , Anastasia Yendiki , Martin Reuter

Diffusion-weighted magnetic resonance imaging (DW-MRI) can be used to characterise the microstructure of the nervous tissue, e.g. to delineate brain white matter connections in a non-invasive manner via fibre tracking. Magnetic Resonance…

Two ubiquitous aspects of large-scale data analysis are that the data often have heavy-tailed properties and that diffusion-based or spectral-based methods are often used to identify and extract structure of interest. Perhaps surprisingly,…

Machine Learning · Computer Science 2010-05-11 Michael W. Mahoney , Hariharan Narayanan

Streamline classification is essential to identify anatomically meaningful white matter tracts from diffusion MRI (dMRI) tractography. However, current streamline classification methods rely primarily on the geometric features of the…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Haotian Yan , Bocheng Guo , Jianzhong He , Nir A. Sochen , Ofer Pasternak , Lauren J O'Donnell , Fan Zhang

In complex visual recognition tasks it is typical to adopt multiple descriptors, that describe different aspects of the images, for obtaining an improved recognition performance. Descriptors that have diverse forms can be fused into a…

Computer Vision and Pattern Recognition · Computer Science 2015-06-15 Jayaraman J. Thiagarajan , Karthikeyan Natesan Ramamurthy , Andreas Spanias

In structural brain networks the connections of interest consist of white-matter fibre bundles between spatially segregated brain regions. The presence, location and orientation of these white matter tracts can be derived using diffusion…

Neurons and Cognition · Quantitative Biology 2012-02-09 M. Hinne , T. Heskes , M. A. J. van Gerven

A large number of mathematical models have been proposed to describe the measured signal in diffusion-weighted (DW) magnetic resonance imaging (MRI) and infer properties about the white matter microstructure. However, a head-to-head…

Purpose: Diffusion weighted MRI (dMRI) and its models of neural structure provide insight into human brain organization and variations in white matter. A recent study by McMaster, et al. showed that complex graph measures of the connectome,…

The compositionality and sparsity of high-throughput sequencing data poses a challenge for regression and classification. However, in microbiome research in particular, conditional modeling is an essential tool to investigate relationships…

Machine Learning · Statistics 2023-07-19 Shimeng Huang , Elisabeth Ailer , Niki Kilbertus , Niklas Pfister

Parcellation of whole-brain tractography streamlines is an important step for tract-based analysis of brain white matter microstructure. Existing fiber parcellation approaches rely on accurate registration between an atlas and the…

Image and Video Processing · Electrical Eng. & Systems 2019-12-24 Feihong Liu , Jun Feng , Geng Chen , Ye Wu , Yoonmi Hong , Pew-Thian Yap , Dinggang Shen

Segmenting white matter bundles from human tractograms is a task of interest for several applications. Current methods for bundle segmentation consider either only prior knowledge about the relative anatomical position of a bundle, or only…

Image and Video Processing · Electrical Eng. & Systems 2019-07-17 Giulia Bertò , Paolo Avesani , Franco Pestilli , Daniel Bullock , Bradley Caron , Emanuele Olivetti

In statistical machine learning, kernel methods allow to consider infinite dimensional feature spaces with a computational cost that only depends on the number of observations. This is usually done by solving an optimization problem…

Optimization and Control · Mathematics 2019-01-17 Guillaume Garrigos , Lorenzo Rosasco , Silvia Villa

White matter microstructure underpins cognition and function in the human brain through the facilitation of neuronal communication, and the non-invasive characterization of this structure remains a research frontier in the neuroscience…

Fiber tractography is an important tool of computational neuroscience that enables reconstructing the spatial connectivity and organization of white matter of the brain. Fiber tractography takes advantage of diffusion Magnetic Resonance…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 Tomer Weiss , Sanketh Vedula , Ortal Senouf , Oleg Michailovich , AlexBronstein

Tractography fiber clustering using diffusion MRI (dMRI) is a crucial method for white matter (WM) parcellation to enable analysis of brains structural connectivity in health and disease. Current fiber clustering strategies primarily use…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Bocheng Guo , Jin Wang , Yijie Li , Junyi Wang , Mingyu Gao , Puming Feng , Yuqian Chen , Jarrett Rushmore , Nikos Makris , Yogesh Rathi , Lauren J O'Donnell , Fan Zhang

We present the concept of fiber-flux density for locally quantifying white matter (WM) fiber bundles. By combining scalar diffusivity measures (e.g., fractional anisotropy) with fiber-flux measurements, we define new local descriptors…

Computer Vision and Pattern Recognition · Computer Science 2017-09-20 Itay Benou , Ronel Veksler , Alon Friedman , Tammy Riklin Raviv

Tractography from high-dimensional diffusion magnetic resonance imaging (dMRI) data allows brain's structural connectivity analysis. Recent dMRI studies aim to compare connectivity patterns across subject groups and disease populations to…

A novel approach is presented for group statistical analysis of diffusion weighted MRI datasets through voxelwise Orientation Distribution Functions (ODF). Recent advances in MRI acquisition make it possible to use high quality diffusion…

Medical Physics · Physics 2019-05-13 Steven H. Baete , Jingyun Chen , Ying-Chia Lin , Xiuyuan Wang , Ricardo Otazo , Fernando E. Boada

Diffusion-weighted magnetic resonance imaging (dMRI) is widely used to assess the brain white matter. One of the most common computations in dMRI involves cross-subject tract-specific analysis, whereby dMRI-derived biomarkers are compared…

Image and Video Processing · Electrical Eng. & Systems 2023-07-12 Davood Karimi , Hamza Kebiri , Ali Gholipour