Related papers: Principal Process Analysis of dynamic GlucoCEST MR…
Diabetes is a chronic condition, considered one of the civilization diseases, that is characterized by sustained high blood sugar levels. There is no doubt that more and more people is going to suffer from diabetes, hence it is crucial to…
A device based on Polarization sensitive optical coherence tomography is developed to monitor blood glucose levels in human subjects. The device was initially tested with tissue phantom. The measurements with human subjects for various…
Diabetes is a chronicle disease where the body of a human is irregular to dissolve the blood glucose properly. The diabetes is due to lack of insulin in human body. The continuous monitoring of blood glucose is main important aspect for…
Metabolic heterogeneity is widely recognised as the next challenge in our understanding of non-genetic variation. A growing body of evidence suggests that metabolic heterogeneity may result from the inherent stochasticity of intracellular…
A task of vital clinical importance, within Diabetes management, is the prevention of hypo/hyperglycemic events. Increasingly adopted Continuous Glucose Monitoring (CGM) devices offer detailed, non-intrusive and real time insights into a…
Diabetes mellitus is a complex group of syndromes that have in common a disturbance in the body's use of glucose, resulting in an elevated blood sugar. Once detected, sugar diabetes can be controlled by an appropriate regimen that should…
Purpose: Dynamic glucose enhanced (DGE) MRI studies employ chemical exchange saturation transfer (CEST) or spin lock (CESL) to study glucose uptake. Currently, these methods are hampered by low effect size and sensitivity to motion. To…
Standard objective functions used during the training of neural-network-based predictive models do not consider clinical criteria, leading to models that are not necessarily clinically acceptable. In this study, we look at this problem from…
This study investigates the dynamics of red blood cells (RBCs) under the influence of evanescent waves generated by total internal reflection (TIR). Using a 1064 nm laser system and a dual-chamber prism setup, we quantified the mobility of…
This paper shows results of computer analysis of images in the purpose of finding differences between medical images in order of their classifications in terms of separation malign tissue from a normal and benign tissue. The diagnostics of…
The energetics of cerebral activity critically relies on the functional and metabolic interactions between neurons and astrocytes. Important open questions include the relation between neuronal versus astrocytic energy demand, glucose…
Due to the sensitive nature of diabetes-related data, preventing them from being shared between studies, progress in the field of glucose prediction is hard to assess. To address this issue, we present GLYFE (GLYcemia Forecasting…
An algorithm based on PLS regression has been developed and optimized for measuring blood glucose level using the infra-red transmission spectrum of blood samples. A set of blood samples were tagged with their glucose concentration using an…
In this paper, we build a new, simple, and interpretable mathematical model to estimate and forecast physiology related to the human glucose-insulin system, constrained by available data. By constructing a simple yet flexible model class…
In biomedical applications it is often necessary to estimate a physiological response to a treatment consisting of multiple components, and learn the separate effects of the components in addition to the joint effect. Here, we extend…
Model-driven analysis of biophysical phenomena is gaining increased attention and utility for medical imaging applications. In magnetic resonance imaging (MRI), the availability of well-established models for describing the relations…
Contrast agents in dynamic contrast enhanced magnetic resonance imaging allow to localize tumors and observe their contrast kinetics, which is essential for cancer characterization and respective treatment decision-making. However, contrast…
Intracellular structural alterations are hallmark of several disease conditions and treatment modalities. However, robust methods to quantify these changes are scarce. In view of this, we introduce a new method to quantify structural…
Despite its benefits for tumour detection and treatment, the administration of contrast agents in dynamic contrast-enhanced MRI (DCE-MRI) is associated with a range of issues, including their invasiveness, bioaccumulation, and a risk of…
The increasing number of diabetic patients is a serious issue in society today, which has significant negative impacts on people's health and the country's financial expenditures. Because diabetes may develop into potential serious…