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Optical microscopy has so far been restricted to superficial layers, leaving many important biological questions unanswered. Random scattering causes the ballistic focus, which is conventionally used for image formation, to decay…

Optics · Physics 2012-08-28 Ke Si , Reto Fiolka , Meng Cui

Meniscal tear in the knee joint is a highly common injury that can require an ablation. However, the success rate of meniscectomy is highly impacted by difficulties in estimating the thin vascularization of the meniscus, which determines…

Medical Physics · Physics 2023-01-05 Baptiste Pialot , Adeline Bernard , Herve Liebgott , François Varray

X-ray microtomography is a versatile tool allowing the measurement of the 3D structure of optically thick samples. As a non-destructive technique, it is readily adapted to 4D imaging, where a sample can be monitored over time, and…

Instrumentation and Detectors · Physics 2025-12-17 Harry Allan , Tom Partridge , Joseph Jacob , Marco Endrizzi

Ultrasound contrast agents comprise gas microbubbles surrounded by stabilising elastic or viscoelastic shells. Microbubbles containing liquid or solid cores are referred to as antibubbles. The manufacturing process of long-lived antibubbles…

For several centuries, far-field optical microscopy has remained a key instrument in many scientific disciplines including physical, chemical and biomedical research. Nonetheless, far-field imaging has many limitations: the spatial…

Optics · Physics 2020-01-27 Lyubov V. Amitonova , Johannes F. de Boer

Recent investigations have established the physical relevance of spatially-localized instability mechanisms in fluid dynamics and their potential for technological innovations in flow control. In this letter, we show that the mathematical…

Fluid Dynamics · Physics 2024-11-11 Talha Mushtaq , Maziar S. Hemati

Super-resolution is an ill-posed problem, where a ground-truth high-resolution image represents only one possibility in the space of plausible solutions. Yet, the dominant paradigm is to employ pixel-wise losses, such as L_1, which drive…

Computer Vision and Pattern Recognition · Computer Science 2021-11-08 Andreas Lugmayr , Martin Danelljan , Fisher Yu , Luc Van Gool , Radu Timofte

We propose an ultrasound approach which provides, with one single examination and one single device, access to three bone biomarkers: anatomy, tissue quality and blood flow. It unlocks ultrasound imaging inside bone by accounting for…

The discovery and understanding of many ultrafast dynamical processes are often invaluable. This paper is the first report to apply optical parametric amplification to implement single-shot ultrafast imaging with high space and time…

Ultrasound imaging, as a noninvasive, real-time, and low-cost modality, plays a vital role in clinical diagnosis, catheterization intervention, and portable devices. With the development of transducer hardware and the continuous progress of…

Medical Physics · Physics 2025-07-22 Xuyang Chen , Mingtong Chen , Zhengbao Yang

We went below the MRI acceleration factors (a.k.a., k-space undersampling) reported by all published papers that reference the original fastMRI challenge, and then considered powerful deep learning based image enhancement methods to…

Computer Vision and Pattern Recognition · Computer Science 2021-10-01 Aleksandr Belov , Joel Stadelmann , Sergey Kastryulin , Dmitry V. Dylov

In the case of vector flow imaging systems, the most employed flow estimation techniques are the directional beamforming based cross correlation and the triangulation-based autocorrelation. However, the directional beamforming-based…

Signal Processing · Electrical Eng. & Systems 2022-06-07 A. N. Madhavanunni , Mahesh Raveendranatha Panicker

In many imaging applications where segmented features (e.g. blood vessels) are further used for other numerical simulations (e.g. finite element analysis), the obtained surfaces do not have fine resolutions suitable for the task. Increasing…

Analysis of PDEs · Mathematics 2023-09-19 Yiyao Zhang , Ke Chen , Shang-Hua Yang

Magnetic Resonance Spectroscopic Imaging (MRSI) is an essential tool for quantifying metabolites in the body, but the low spatial resolution limits its clinical applications. Deep learning-based super-resolution methods provided promising…

Image and Video Processing · Electrical Eng. & Systems 2022-07-22 Siyuan Dong , Gilbert Hangel , Eric Z. Chen , Shanhui Sun , Wolfgang Bogner , Georg Widhalm , Chenyu You , John A. Onofrey , Robin de Graaf , James S. Duncan

Integrated photonic sensors can provide large scale, flexible detection schemes. Photonic crystal slabs (PCS) offer a miniaturized platform for wideband, sensitive ultrasound detection by exploiting the photoelastic effect in water.…

Applied Physics · Physics 2021-08-17 Eric Y. Zhu , Maria Charles-Herrera , Cory Rewcastle , Raanan Gad , Li Qian , Ofer Levi

In the recent years, we witness a great interest in imaging, in a wide sense, using contrast agents. One of the reasons is that many imaging modalities, as the ones related to medical sciences, suffer from several shortcomings. The most…

Optics · Physics 2020-08-28 Ahcene Ghandriche , Mourad Sini

We present energy-resolved photoelectron momentum maps for orbital tomography that have been collected with a novel and efficient time-of-flight momentum microscopy setup. This setup is combined with a 0.5 MHz table-top femtosecond…

An interferometric fluorescent microscope and a novel theoretic image reconstruction approach were developed and used to obtain super-resolution images of live biological samples and to enable dynamic real time tracking. The tracking…

Understanding the three-dimensional motion of bubbles is essential for interpreting transport and mixing in multiphase flows, especially when bubbles deform under shear or move rapidly through the flow field. In many laboratory setups, only…

Fluid Dynamics · Physics 2026-01-30 Chaitanya S Nayak , Faizaan Mohammed , Vivek Kumar , Shivam Prajapati , Cyrus Aidun

4D flow MRI is a non-invasive imaging method that can measure blood flow velocities over time. However, the velocity fields detected by this technique have limitations due to low resolution and measurement noise. Coordinate-based neural…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Simone Saitta , Marcello Carioni , Subhadip Mukherjee , Carola-Bibiane Schönlieb , Alberto Redaelli