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Epidemic containment is a major concern when confronting large-scale infections in complex networks. Many works have been devoted to analytically understand how to restructure the network to minimize the impact of major outbreaks of…

Physics and Society · Physics 2018-12-27 Joan T. Matamalas , Alex Arenas , Sergio Gómez

We study delay-independent stability in nonlinear models with a distributed delay which have a positive equilibrium. Such models frequently occur in population dynamics and other applications. In particular, we construct a relevant…

Dynamical Systems · Mathematics 2009-01-12 Elena Braverman , Sergey Zhukovskiy

Social distancing has been enacted in order to mitigate the spread of COVID-19. Like many authors, we adopt the classic epidemic SIR model, where the infection rate is the control variable. Its differential flatness property yields ele…

Systems and Control · Electrical Eng. & Systems 2022-10-05 Michel Fliess , Cédric Join , Alberto d'Onofrio

This paper combines a canonical epidemiology model of disease dynamics with government policy of lockdown and testing, and agents' decision to social distance in order to avoid getting infected. The model is calibrated with data on deaths…

General Economics · Economics 2022-02-10 Shomak Chakrabarti , Ilia Krasikov , Rohit Lamba

We consider an epidemiological model that includes waning and boosting of immunity. Assuming that repeated exposure to the pathogen fully restores immunity, we derive an SIRS-type model with discrete and distributed delays. First we prove…

Dynamical Systems · Mathematics 2016-06-14 Maria Vittoria Barbarossa , Monika Polner , Gergely Röst

A two-dimensional system of differential equations with delay modelling the glucose-insulin interaction processes in the human body is considered. Sufficient conditions are derived for the unique positive equilibrium in the system to be…

Dynamical Systems · Mathematics 2020-12-11 M. Angelova , G. Beliakov , A. Ivanov , S. Shelyag

In this paper, we investigate global dynamics for a system of delay differential equations which describes a virus-immune interaction in \textit{vivo}. The model has two distributed time delays describing time needed for infection of cell…

Dynamical Systems · Mathematics 2010-08-17 Yukihiko Nakata

The contact process, or SIS epidemic, is a continuous-time Markov process used to model the spread of infection on a graph. Each vertex is either healthy or infected, and each infected vertex independently infects each of its healthy…

Probability · Mathematics 2025-12-09 Shirshendu Chatterjee , David Sivakoff , Matthew Wascher

The ubiquity of oscillations in epidemics presents a long standing challenge for the formulation of epidemic models. Whether they are external and seasonally driven, or arise from the intrinsic dynamics is an open problem. It is known that…

Populations and Evolution · Quantitative Biology 2011-09-06 S. Goncalves , G. Abramson , M. F. C. Gomes

Epidemic models are useful tools in the fight against infectious diseases, as they allow policy makers to test and compare various strategies to limit disease transmission while mitigating collateral damage on the economy. Epidemic models…

Populations and Evolution · Quantitative Biology 2021-08-18 Joseph D. Peterson , Ronojoy Adhikari

The SIR model is a three-compartment model of the time development of an epidemic. After normalizing the dependent variables, the model is a system of two non-linear differential equations for the susceptible proportion $S$ and the infected…

Dynamical Systems · Mathematics 2021-04-27 William G. Faris

We analyze the identifiability and observability of the well-known SIR epidemic model with an additional compartment Q of the sub-population of infected individuals that are placed in quarantine (SIQR model), considering that the flow of…

Dynamical Systems · Mathematics 2021-03-09 Frédéric Hamelin , Abderrahman Iggidr , Alain Rapaport , Gauthier Sallet , Max Souza

The spread of COVID-19 has been thwarted in most countries through non-pharmaceutical interventions. In particular, the most effective measures in this direction have been the stay-at-home and closure strategies of businesses and schools.…

Physics and Society · Physics 2022-05-04 G. Dimarco , G. Toscani , M. Zanella

This paper considers the classical Susceptible--Infected--Susceptible (SIS) network epidemic model, which describes a disease spreading through $n$ nodes, with the network links governing the possible transmission pathways of the disease…

Systems and Control · Electrical Eng. & Systems 2023-05-29 Liam Walsh , Mengbin Ye , Brian D. O. Anderson , Zhiyong Sun

In this paper, we study a novel control method for a generalized SIS epidemic process. In particular, we use predictive control to design optimal protective resource distribution strategies which balance the need to eliminate the epidemic…

Optimization and Control · Mathematics 2018-08-17 Nicholas J. Watkins , George J. Pappas

A delayed model describing the dynamics of HIV (Human Immunodeficiency Virus) with CTL (Cytotoxic T Lymphocytes) immune response is investigated. The model includes four nonlinear differential equations describing the evolution of…

Optimization and Control · Mathematics 2018-06-13 Karam Allali , Sanaa Harroudi , Delfim F. M. Torres

Networks of contacts capable of spreading infectious diseases are often observed to be highly heterogeneous, with the majority of individuals having fewer contacts than the mean, and a significant minority having relatively very many…

Physics and Society · Physics 2016-12-21 César Parra-Rojas , Thomas House , Alan J. McKane

Partial differential equation (PDE) models for infectious disease have received renewed interest in recent years. Most models of this type extend classical compartmental formulations with additional terms accounting for spatial dynamics,…

Populations and Evolution · Quantitative Biology 2025-04-29 Pierluigi Colli , Gabriela Marinoschi , Elisabetta Rocca , Alex Viguerie

In the wake of epidemics, quarantine measures are typically recommended by health authorities or governments to help control the spread of the disease. Compared with mandatory quarantine, voluntary quarantine offers individuals the liberty…

Physics and Society · Physics 2024-03-14 Simiao Shi , Zhiyuan Wang , Xingru Chen , Feng Fu

We study a discrete Susceptible-Infected-Recovered (SIR) model for the spread of infectious disease on a homogeneous tree and the limit behavior of the model in the case when the tree vertex degree tends to infinity. We obtain the…

Probability · Mathematics 2022-07-08 Alexander Gairat , Vadim Shcherbakov