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A significant challenge in molecular dynamics (MD) simulations is ensuring that sampled configurations converge to the equilibrium or nonequilibrium stationary distribution of interest. Lack of convergence constrains the estimation of free…

Computational Physics · Physics 2026-04-03 Sagar Kania , Robert J. Webber , Gideon Simpson , David Aristoff , Daniel M. Zuckerman

We propose a genetic algorithm powered evolution (GAPE) method to create deep learning solutions for energy and position estimation for reactor antineutrino interactions in the Precision Reactor Oscillation and Spectrum Experiment…

Combustion process can become more energy efficient and environment friendly if used with appropriate fuel additive. Discovery of fuel additive can be accelerated by applying hybrid approach of using of chemical kinetics and Machine…

Chemical Physics · Physics 2021-11-12 Shahid Rabbani

Achieving both realism and controllability in closed-loop traffic simulation remains a key challenge in autonomous driving. Dataset-based methods reproduce realistic trajectories but suffer from covariate shift in closed-loop deployment,…

Robotics · Computer Science 2025-09-23 Keyu Chen , Wenchao Sun , Hao Cheng , Sifa Zheng

The application of deep neural networks (DNNs) holds considerable promise as a substitute for the direct integration of chemical source terms in combustion simulations. However, challenges persist in ensuring high precision and…

Fluid Dynamics · Physics 2023-12-29 Han Li , Ruixin Yang , Min Zhang , Runze Mao , Zhi X. Chen

Dynamic Treatment Regimes (DTRs) provide a systematic framework for optimizing sequential decision-making in chronic disease management, where therapies must adapt to patients' evolving clinical profiles. Inverse probability weighting (IPW)…

Methodology · Statistics 2026-03-26 Chloe Si , David A. Stephens , Erica E. M. Moodie

Identifying T-cell receptors (TCRs) that interact with antigenic peptides provides the technical basis for developing vaccines and immunotherapies. The emergent deep learning methods excel at learning antigen binding patterns from known…

Quantitative Methods · Quantitative Biology 2024-11-28 Jiangbin Zheng , Qianhui Xu , Ruichen Xia , Stan Z. Li

Identifying reaction coordinates (RCs) is a key to understanding the mechanism of reactions in complex systems. Deep neural network (DNN) and machine learning approaches have become a powerful tool to find the RC. On the other hand, the…

Chemical Physics · Physics 2025-02-21 Kyohei Kawashima , Takumi Sato , Kei-ichi Okazaki , Kang Kim , Nobuyuki Matubayasi , Toshifumi Mori

This paper introduces PowerDAG, an agentic AI system for automating complex distribution-grid analysis. We address the reliability challenges of state-of-the-art agentic systems in automating complex engineering workflows by introducing two…

Systems and Control · Electrical Eng. & Systems 2026-04-23 Emmanuel O. Badmus , Amritanshu Pandey

We introduce a new shrinkage variable selection operator for linear models which we term the \emph{adaptive ridge selector} (ARiS). This approach is inspired by the \emph{relevance vector machine} (RVM), which uses a Bayesian hierarchical…

Methodology · Statistics 2008-05-28 Artin Armagan , Russell Zaretzki

Utilization of liquid fuels is crucial to enabling commercialization of rotating detonation engines in the near future. In this study, Eulerian-Lagrangian simulations are conducted for rotating detonative combustion with dilute n-heptane…

Fluid Dynamics · Physics 2022-02-15 Shan Jin , Chao Xu , Hongtao Zheng , Huangwei Zhang

The optimal execution problem has always been a continuously focused research issue, and many reinforcement learning (RL) algorithms have been studied. In this article, we consider the execution problem of targeting the volume weighted…

Optimization and Control · Mathematics 2024-11-12 Xingyu Zhou , Wenbin Chen , Mingyu Xu

Self-evolution is indispensable to realize full autonomous driving. This paper presents a self-evolving decision-making system based on the Integrated Decision and Control (IDC), an advanced framework built on reinforcement learning (RL).…

Robotics · Computer Science 2022-10-20 Yang Guan , Liye Tang , Chuanxiao Li , Shengbo Eben Li , Yangang Ren , Junqing Wei , Bo Zhang , Keqiang Li

Instanton theory is an established method to calculate rate constants of chemical reactions including atom tunneling. Technical and methodological improvements increased its applicability. Still, a large number of energy and gradient…

Chemical Physics · Physics 2020-09-10 Jan Meisner , Johannes Kästner

Identification of drug-target interactions (DTIs) plays a key role in drug discovery. The high cost and labor-intensive nature of in vitro and in vivo experiments have highlighted the importance of in silico-based DTI prediction approaches.…

Quantitative Methods · Quantitative Biology 2019-09-11 Ingoo Lee , Jongsoo Keum , Hojung Nam

This paper describes an approach for attractor selection (or multi-stability control) in nonlinear dynamical systems with constrained actuation. Attractor selection is obtained using two different deep reinforcement learning methods: 1) the…

Systems and Control · Electrical Eng. & Systems 2020-06-02 Xue-She Wang , James D. Turner , Brian P. Mann

Effective patient monitoring is vital for timely interventions and improved healthcare outcomes. Traditional monitoring systems often struggle to handle complex, dynamic environments with fluctuating vital signs, leading to delays in…

Machine Learning · Computer Science 2024-10-30 Thanveer Shaik , Xiaohui Tao , Lin Li , Haoran Xie , Hong-Ning Dai , Feng Zhao , Jianming Yong

The rehearsal strategy is widely used to alleviate the catastrophic forgetting problem in class incremental learning (CIL) by preserving limited exemplars from previous tasks. With imbalanced sample numbers between old and new classes, the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-28 Xiuwei Chen , Xiaobin Chang

Several novel statistical methods have been developed to estimate large integrated volatility matrices based on high-frequency financial data. To investigate their asymptotic behaviors, they require a sub-Gaussian or finite high-order…

Statistics Theory · Mathematics 2023-08-15 Minseok Shin , Donggyu Kim , Jianqing Fan

This study proposes an algorithm to synthesize controllers for the power management on board hybrid vehicles that allows the vehicle to reach its maximum range along a given route. The algorithm stems from a level-set approach that computes…

Optimization and Control · Mathematics 2012-09-27 Giovanni Granato
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