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Ovarian cancer detection has traditionally relied on a multi-step process that includes biopsy, tissue staining, and morphological analysis by experienced pathologists. While widely practiced, this conventional approach suffers from several…

A large part of the current success of deep learning lies in the effectiveness of data -- more precisely: labelled data. Yet, labelling a dataset with human annotation continues to carry high costs, especially for videos. While in the image…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Yuki M. Asano , Mandela Patrick , Christian Rupprecht , Andrea Vedaldi

Despite fluorescent cell-labelling being widely employed in biomedical studies, some of its drawbacks are inevitable, with unsuitable fluorescent probes or probes inducing a functional change being the main limitations. Consequently, the…

Quantitative Methods · Quantitative Biology 2020-03-03 Yan Ge , Philipp Rosendahl , Claudio Durán , Nicole Töpfner , Sara Ciucci , Jochen Guck , Carlo Vittorio Cannistraci

Hyperspectral image analysis has become an important topic widely researched by the remote sensing community. Classification and segmentation of such imagery help understand the underlying materials within a scanned scene, since…

Computer Vision and Pattern Recognition · Computer Science 2020-12-02 Jakub Nalepa , Michal Myller , Yasuteru Imai , Ken-ichi Honda , Tomomi Takeda , Marek Antoniak

We propose a selective learning method using meta-learning and deep reinforcement learning for medical image interpretation in the setting of limited labeling resources. Our method, MedSelect, consists of a trainable deep learning selector…

Computer Vision and Pattern Recognition · Computer Science 2021-03-29 Akshay Smit , Damir Vrabac , Yujie He , Andrew Y. Ng , Andrew L. Beam , Pranav Rajpurkar

Purpose: In digital histopathology, virtual multi-staining is important for diagnosis and biomarker research. Additionally, it provides accurate ground-truth for various deep-learning tasks. Virtual multi-staining can be obtained using…

Image and Video Processing · Electrical Eng. & Systems 2023-12-15 Johannes Lotz , Nick Weiss , Jeroen van der Laak , Stefan Heldmann

Unlike other histology analysis, classification of tubule status in testis histology is very challenging due to their high similarity of texture and shape. Traditional deep learning networks have difficulties to capture nuance details among…

Computer Vision and Pattern Recognition · Computer Science 2017-07-20 Chia-Yu Kao , Leonard McMillan

Data cleaning consumes about 80% of the time spent on data analysis for clinical research projects. This is a much bigger problem in the era of big data and machine learning in the field of medicine where large volumes of data are being…

Medical Physics · Physics 2018-01-03 Timothy Rozario , Troy Long , Mingli Chen , Weiguo Lu , Steve Jiang

We present an unsupervised deep learning method for text line segmentation that is inspired by the relative variance between text lines and spaces among text lines. Handwritten text line segmentation is important for the efficiency of…

Computer Vision and Pattern Recognition · Computer Science 2020-10-27 Berat Kurar Barakat , Ahmad Droby , Rym Alasam , Boraq Madi , Irina Rabaev , Raed Shammes , Jihad El-Sana

In the medical domain, the lack of large training data sets and benchmarks is often a limiting factor for training deep neural networks. In contrast to expensive manual labeling, computer simulations can generate large and fully labeled…

Most existing works in few-shot learning rely on meta-learning the network on a large base dataset which is typically from the same domain as the target dataset. We tackle the problem of cross-domain few-shot learning where there is a large…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Ashraful Islam , Chun-Fu Chen , Rameswar Panda , Leonid Karlinsky , Rogerio Feris , Richard J. Radke

Here we report a method for visualization of volumetric structural information of live biological samples with no exogenous contrast agents. The process is made possible through a technique that involves generation, synthesis and analysis…

Deep learning has significantly advanced medical imaging analysis (MIA), achieving state-of-the-art performance across diverse clinical tasks. However, its success largely depends on large-scale, high-quality labeled datasets, which are…

Computer Vision and Pattern Recognition · Computer Science 2025-05-09 Cheng Jin , Zhengrui Guo , Yi Lin , Luyang Luo , Hao Chen

Joint analysis of multiple biomarker images and tissue morphology is important for disease diagnosis, treatment planning and drug development. It requires cross-staining comparison among Whole Slide Images (WSIs) of immuno-histochemical and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-05 Abubakr Shafique , Morteza Babaie , Mahjabin Sajadi , Adrian Batten , Soma Skdar , H. R. Tizhoosh

Histological visualizations are critical to clinical disease management and are fundamental to biological understanding. However, current approaches that rely on bright-field microscopy require extensive tissue preparation prior to imaging.…

It is a critical task to evalaute HER2 expression level accurately for breast cancer evaluation and targeted treatment therapy selection. However, the standard multi-step Immunohistochemistry (IHC) staining is resource-intensive, expensive,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Peide Zhu , Linbin Lu , Zhiqin Chen , Xiong Chen

These days deep learning is the fastest-growing area in the field of Machine Learning. Convolutional Neural Networks are currently the main tool used for image analysis and classification purposes. Although great achievements and…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Agnieszka Mikołajczyk , Michał Grochowski

Semi-supervised learning for medical image segmentation presents a unique challenge of efficiently using limited labeled data while leveraging abundant unlabeled data. Despite advancements, existing methods often do not fully exploit the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-12 Bin Zhao , Chunshi Wang , Shuxue Ding

Histopathology image analysis plays a critical role in cancer diagnosis and treatment. To automatically segment the cancerous regions, fully supervised segmentation algorithms require labor-intensive and time-consuming labeling at the pixel…

Image and Video Processing · Electrical Eng. & Systems 2019-08-29 Gang Xu , Zhigang Song , Zhuo Sun , Calvin Ku , Zhe Yang , Cancheng Liu , Shuhao Wang , Jianpeng Ma , Wei Xu

Deep learning-based analysis of high-frequency, high-resolution micro-ultrasound data shows great promise for prostate cancer detection. Previous approaches to analysis of ultrasound data largely follow a supervised learning paradigm.…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Paul F. R. Wilson , Mahdi Gilany , Amoon Jamzad , Fahimeh Fooladgar , Minh Nguyen Nhat To , Brian Wodlinger , Purang Abolmaesumi , Parvin Mousavi
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