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Clinical trials of a vaccine during an epidemic face particular challenges, such as the pressure to identify an effective vaccine quickly to control the epidemic, and the effect that time-space-varying infection incidence has on the power…

Populations and Evolution · Quantitative Biology 2021-05-21 Rob Johnson , Chris Jackson , Anne Presanis , Sofia S. Villar , Daniela De Angelis

Facing a global epidemic of new infectious diseases such as COVID-19, non-pharmaceutical interventions (NPIs), which reduce transmission rates without medical actions, are being implemented around the world to mitigate spreads. One of the…

Populations and Evolution · Quantitative Biology 2021-03-04 Naoya Fujiwara , Tomokatsu Onaga , Takayuki Wada , Shouhei Takeuchi , Junji Seto , Tomoki Nakaya , Kazuyuki Aihara

A new age-distributed immuno-epidemiological model with information-based vaccine uptake suggested in this work represents a system of integro-differential equations for the numbers of susceptible individuals, infected individuals,…

Populations and Evolution · Quantitative Biology 2024-04-02 Samiran Ghosh , Malay Banerjee , Vitaly Volpert

Until a vaccine or therapy is found against the SARS-CoV-2 coronavirus, reaching herd immunity appears to be the only mid-term option. However, if the number of infected individuals decreases and eventually fades only beyond this threshold,…

Optimization and Control · Mathematics 2020-06-11 Pierre-Alexandre Bliman , Michel Duprez , Yannick Privat , Nicolas Vauchelet

Given an aftermath of a cascade in the network, i.e. a set $V_I$ of "infected" nodes after an epidemic outbreak or a propagation of rumors/worms/viruses, how can we infer the sources of the cascade? Answering this challenging question is…

Social and Information Networks · Computer Science 2016-08-24 Hung T. Nguyen , Preetam Ghosh , Michael L. Mayo , Thang N. Dinh

Epidemic threshold is one of the most important features of the epidemic dynamics. Through a lot of numerical simulations in classic Susceptible-Infected-Recovered (SIR) and Susceptible-Infected-Susceptible (SIS) models on various types of…

Physics and Society · Physics 2014-10-16 Panpan Shu , Wei Wang , Ming Tang , Younghae Do

Epidemic spread on networks is one of the most studied dynamics in network science and has important implications in real epidemic scenarios. Nonetheless, the dynamics of real epidemics and how it is affected by the underline structure of…

Physics and Society · Physics 2020-09-08 Bnaya Gross , Shlomo Havlin

We introduce a novel compartmental model accounting for the effects of vaccine efficacy, deployment rates and timing of initiation of deployment. We simulate different scenarios and initial conditions, and we find that higher abundancy and…

Populations and Evolution · Quantitative Biology 2022-06-28 Omar El Deeb , Maya Jalloul

This paper develops an individual-based stochastic network SIR model for the empirical analysis of the Covid-19 pandemic. It derives moment conditions for the number of infected and active cases for single as well as multigroup epidemic…

Econometrics · Economics 2022-01-05 M. Hashem Pesaran , Cynthia Fan Yang

We consider the simple epidemiological SIS model for a general heterogeneous population introduced by Lajmanovich and Yorke (1976) in finite dimension, and its infinite dimensional generalization we introduced in previous works. In this…

Dynamical Systems · Mathematics 2022-11-29 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

When modelling epidemics or spread of information on online social networks, it is crucial to include not just the density of the connections through which infections can be transmitted, but also the variability of susceptibility. Different…

Physics and Society · Physics 2020-02-18 Ágnes Backhausz , Edit Bognár

The resurgence of measles is largely attributed to the decline in vaccine adoption and the increase in mobility. Although the vaccine for measles is readily available and highly successful, its current adoption is not adequate to prevent…

Populations and Evolution · Quantitative Biology 2020-08-26 Sheryl L. Chang , Mahendra Piraveenan , Mikhail Prokopenko

This paper studies algorithmic strategies to effectively reduce the number of infections in susceptible-infected-recovered (SIR) epidemic models. We consider a Markov chain SIR model and its two instantiations in the deterministic SIR…

Optimization and Control · Mathematics 2020-11-24 Yuhao Yi , Liren Shan , Philip E. Paré , Karl H. Johansson

We consider an epidemic process on adaptive activity-driven temporal networks, with adaptive behaviour modelled as a change in activity and attractiveness due to infection. By using a mean-field approach, we derive an analytical estimate of…

Physics and Society · Physics 2020-09-02 Marco Mancastroppa , Raffaella Burioni , Vittoria Colizza , Alessandro Vezzani

Random mixing in host populations has been a convenient simplifying assumption in the study of epidemics, but neglects important differences in contact rates within and between population groups. For HIV/AIDS, the assumption of random…

Quantitative Methods · Quantitative Biology 2016-02-24 Brian G. Williams , Christopher Dye

We study the optimal control problem of maximizing the spread of an information epidemic on a social network. Information propagation is modeled as a Susceptible-Infected (SI) process and the campaign budget is fixed. Direct recruitment and…

Social and Information Networks · Computer Science 2016-02-16 Kundan Kandhway , Joy Kuri

We investigate saturation effects in susceptible-infected-susceptible (SIS) models of the spread of epidemics in heterogeneous populations. The structure of interactions in the population is represented by networks with connectivity…

Statistical Mechanics · Physics 2009-11-10 Jaewook Joo , Joel L. Lebowitz

Most researches on adaptive networks mainly concentrate on the properties of steady state, but neglect transient dynamics. In this study, we pay attention to the emergence of community structures in transient process and the effects of…

Physics and Society · Physics 2015-06-05 Hui Yang , Ming Tang , Hai-Feng Zhang

We propose a generative model and an inference scheme for epidemic processes on dynamic, adaptive contact networks. Network evolution is formulated as a link-Markovian process, which is then coupled to an individual-level stochastic SIR…

Methodology · Statistics 2020-04-07 Fan Bu , Allison E. Aiello , Jason Xu , Alexander Volfovsky

Using network-based information to facilitate information spreading is an essential task for spreading dynamics in complex networks, which will benefit the promotion of technical innovations, healthy behaviors, new products, etc. Focusing…

Physics and Society · Physics 2016-06-20 Lei Gao , Wei Wang , Liming Pan , Ming Tang , Hai-Feng Zhang