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We present a fast and accurate analytical method for fluorescence lifetime imaging microscopy (FLIM) using the extreme learning machine (ELM). We used extensive metrics to evaluate ELM and existing algorithms. First, we compared these…

Biological Physics · Physics 2022-03-28 Zhenya Zang , Dong Xiao , Quan Wang , Zinuo Li , Wujun Xie , Yu Chen , David Day Uei Li

Free-form strong-lensing (SL) mass reconstructions typically suffer from overfitting, which manifest itself as false-positive small-scale fluctuations. We present a new free-form MAximum-entropy ReconStruction (${\tt MARS}$) method without…

Cosmology and Nongalactic Astrophysics · Physics 2022-06-08 Sangjun Cha , M. James Jee

Accurate noise estimation is essential for fault-tolerant quantum computing, as decoding performance depends critically on the fidelity of the circuit-level noise parameters. In this work, we introduce a differentiable Maximum Likelihood…

Quantum Physics · Physics 2026-02-24 Hanyan Cao , Dongyang Feng , Cheng Ye , Feng Pan

Objective: To propose and validate an unsupervised MRI reconstruction method that does not require fully sampled k-space data. Materials and Methods: The proposed method, deep image prior with structured sparsity (DISCUS), extends the deep…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Muhammad Ahmad Sultan , Chong Chen , Yingmin Liu , Katarzyna Gil , Karolina Zareba , Rizwan Ahmad

The development of fast and accurate image reconstruction algorithms is a central aspect of computed tomography. In this paper, we investigate this issue for the sparse data problem in photoacoustic tomography (PAT). We develop a direct and…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Stephan Antholzer , Markus Haltmeier , Johannes Schwab

Sparse-view Computed Tomography (CT) is an emerging protocol designed to reduce X-ray dose radiation in medical imaging. Traditional Filtered Back Projection algorithm reconstructions suffer from severe artifacts due to sparse data. In…

Numerical Analysis · Mathematics 2024-12-03 Elena Loli Piccolomini , Davide Evangelista , Elena Morotti

Fluorescence microscopy image (FMI) denoising faces critical challenges due to the compound mixed Poisson-Gaussian noise with strong spatial correlation and the impracticality of acquiring paired noisy/clean data in dynamic biomedical…

Image and Video Processing · Electrical Eng. & Systems 2025-09-25 Jizhihui Liu , Qixun Teng , Qing Ma , Junjun Jiang

Confocal laser-scanning microscopy (CLSM) is one of the most popular optical architectures for fluorescence imaging. In CLSM, a focused laser beam excites the fluorescence emission from a specific specimen position. Some actuators scan the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-10 Alessandro Zunino , Marco Castello , Giuseppe Vicidomini

Convergence of the block iterative method in image reconstruction for positron emission tomography (PET) requires careful control of relaxation parameters, which is a challenging task. The automatic determination of relaxation parameters…

Medical Physics · Physics 2025-01-15 Kibo Ote , Fumio Hashimoto , Yuya Onishi , Yasuomi Ouchi

Recently, the problem of blind image separation has been widely investigated, especially the medical image denoise which is the main step in medical diag-nosis. Removing the noise without affecting relevant features of the image is the main…

Computer Vision and Pattern Recognition · Computer Science 2018-07-11 R. M. Farouk , M. E. Abd El-aziz , A. M. Adam

A key processing step in ground-based astronomy involves combining multiple noisy and blurry exposures to produce an image of the night sky with an improved signal-to-noise ratio. Typically, this is achieved via image coaddition, and can be…

Instrumentation and Methods for Astrophysics · Physics 2025-09-15 Yashil Sukurdeep , Tamás Budavári , Andrew J. Connolly , Fausto Navarro

Low-dose tomography is highly preferred in medical procedures for its reduced radiation risk when compared to standard-dose Computed Tomography (CT). However, the lower the intensity of X-rays, the higher the acquisition noise and hence the…

Image and Video Processing · Electrical Eng. & Systems 2019-12-24 Preeti Gopal , Sharat Chandran , Imants Svalbe , Ajit Rajwade

Imaging the bio-impedance distribution of the brain can provide initial diagnosis of acute stroke. This paper presents a compact and non-radiative tomographic modality, i.e. multi-frequency Electromagnetic Tomography (mfEMT), for the…

Applied Physics · Physics 2020-07-29 Jinxi Xiang , Yonggui Dong , Yunjie Yang

The purpose of this note is to show how the method of maximum entropy in the mean (MEM) may be used to improve parametric estimation when the measurements are corrupted by large level of noise. The method is developed in the context on a…

Machine Learning · Computer Science 2021-08-23 Henryk Gzyl , Enrique ter Horst

Light-field microscopy (LFM) enables rapid volumetric imaging through single-frame acquisition and fast 3D reconstruction algorithms. The high speed and low phototoxicity of LFM make it highly suitable for real-time 3D fluorescence imaging,…

Optics · Physics 2025-02-24 Bohan Qu , Zhouyu Jin , You Zhou , Bo Xiong , Xun Cao

Many computer vision problems can be posed as learning a low-dimensional subspace from high dimensional data. The low rank matrix factorization (LRMF) represents a commonly utilized subspace learning strategy. Most of the current LRMF…

Computer Vision and Pattern Recognition · Computer Science 2016-09-21 Xiangyong Cao , Qian Zhao , Deyu Meng , Yang Chen , Zongben Xu

Multi-frequency Electrical Impedance Tomography (mfEIT) is a promising biomedical imaging technique that estimates tissue conductivities across different frequencies. Current state-of-the-art (SOTA) algorithms, which rely on supervised…

Image and Video Processing · Electrical Eng. & Systems 2024-09-18 Hao Fang , Zhe Liu , Yi Feng , Zhen Qiu , Pierre Bagnaninchi , Yunjie Yang

Sparse-view computed tomography (CT) is a practical solution to reduce radiation dose, but the resulting ill-posed inverse problem poses significant challenges for accurate image reconstruction. Although deep learning and diffusion-based…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Changsheng Fang , Yongtong Liu , Bahareh Morovati , Shuo Han , Yu Shi , Li Zhou , Shuyi Fan , Hengyong Yu

We present a physics-informed deep learning framework to address common limitations in Confocal Laser Scanning Microscopy (CLSM), such as diffraction limited resolution, noise, and undersampling due to low laser power conditions. The…

Materials Science · Physics 2025-01-27 Zaheer Ahmad , Junaid Shabeer , Usman Saleem , Tahir Qadeer , Abdul Sami , Zahira El Khalidi , Saad Mehmood

This paper considers the problem of networks reconstruction from heterogeneous data using a Gaussian Graphical Mixture Model (GGMM). It is well known that parameter estimation in this context is challenging due to large numbers of variables…

Machine Learning · Statistics 2013-10-08 Anani Lotsi , Ernst Wit