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We study the problem of deconvolution for light-sheet microscopy, where the data is corrupted by spatially varying blur and a combination of Poisson and Gaussian noise. The spatial variation of the point spread function (PSF) of a…

The number of noisy images required for molecular reconstruction in single-particle cryo-electron microscopy (cryo-EM) is governed by the autocorrelations of the observed, randomly-oriented, noisy projection images. In this work, we…

Numerical Analysis · Mathematics 2023-05-03 Tamir Bendory , Yuehaw Khoo , Joe Kileel , Oscar Mickelin , Amit Singer

Fluorescence microscopy has enabled a dramatic development in modern biology. Due to its inherently weak signal, fluorescence microscopy is not only much noisier than photography, but also presented with Poisson-Gaussian noise where Poisson…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Yide Zhang , Yinhao Zhu , Evan Nichols , Qingfei Wang , Siyuan Zhang , Cody Smith , Scott Howard

Imaging the bio-impedance distribution of a biological sample can provide understandings about the sample's electrical properties which is an important indicator of physiological status. This paper presents a multi-frequency electromagnetic…

Applied Physics · Physics 2020-07-29 Jinxi Xiang , Zhou Chen , Yonggui Dong , Yunjie Yang

The Segment Anything Model (SAM) achieves strong open-vocabulary segmentation, but its ViT-based image encoders dominate inference latency and memory. Existing activation compression methods, such as token merging, reduce the token length…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Hoai-Chau Tran , Chi H. Nguyen , Duy M. H. Nguyen , Mathias Niepert , Fan Lai , Khoa D. Doan

Objective:Optoacoustic (photoacoustic) tomography is aimed at reconstructing maps of the initial pressure rise induced by the absorption of light pulses in tissue. In practice, due to inaccurate assumptions in the forward model, noise and…

Medical Physics · Physics 2019-01-21 Jaya Prakash , Subhamoy Mandal , Daniel Razansky , Vasilis Ntziachristos

Ultrasound Localization Microscopy (ULM) is a non-invasive technique that allows for the imaging of micro-vessels in vivo, at depth and with a resolution on the order of ten microns. ULM is based on the sub-resolution localization of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-17 Brice Rauby , Paul Xing , Jonathan Porée , Maxime Gasse , Jean Provost

In this paper we aim to tackle the problem of reconstructing a high-resolution image from a single low-resolution input image, known as single image super-resolution. In the literature, sparse representation has been used to address this…

Computer Vision and Pattern Recognition · Computer Science 2016-03-23 Mohammad Rostami , Zhou Wang

Motivation: Cellular Electron CryoTomography (CECT) is an emerging 3D imaging technique that visualizes subcellular organization of single cells at submolecular resolution and in near-native state. CECT captures large numbers of…

Quantitative Methods · Quantitative Biology 2018-05-16 Yixiu Zhao , Xiangrui Zeng , Qiang Guo , Min Xu

Magnetic resonance imaging has been widely applied in clinical diagnosis, however, is limited by its long data acquisition time. Although imaging can be accelerated by sparse sampling and parallel imaging, achieving promising reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Tieyuan Lu , Xinlin Zhang , Yihui Huang , Yonggui Yang , Gang Guo , Lijun Bao , Feng Huang , Di Guo , Xiaobo Qu

Photoacoustic microscopy (PAM) has been a promising biomedical imaging technology in recent years. However, the point-by-point scanning mechanism results in low-speed imaging, which limits the application of PAM. Reducing sampling density…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Jiasheng Zhou , Da He , Xiaoyu Shang , Zhendong Guo , Sung-liang Chen , Jiajia Luo

In this paper, the problem of Magnetic Resonance (MR) image reconstruction from partial Fourier samples has been considered. To this aim, we leverage the evidence that MR images are sparser than their zero-filled reconstructed ones from…

Information Theory · Computer Science 2015-08-19 Fateme Ghayem , Farokh Marvasti

Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…

Medical Physics · Physics 2023-07-18 Pablo Galve , Alejandro Lopez-Montes , Jose M Udias , Stephen C Moore , Joaquin L Herraiz

We consider the problem of finding a sparse solution for an underdetermined linear system of equations when the known parameters on both sides of the system are subject to perturbation. This problem is particularly relevant to…

Systems and Control · Computer Science 2016-06-16 Reza Arablouei

Ultra low radiation dose in X-ray Computed Tomography (CT) is an important clinical objective in order to minimize the risk of carcinogenesis. Compressed Sensing (CS) enables significant reductions in radiation dose to be achieved by…

We present and evaluate the application of the "Reconstructed Image from Simulations Ensemble" (RISE), a novel tomographic image reconstruction method, in infrared tomography. We demonstrate that established methods of photon emission…

Empirical Bayes methods are widely used for large-scale estimation and inference in the Poisson means problem. Existing results establish theoretical properties of the nonparametric maximum likelihood estimator (NPMLE) for optimal posterior…

Statistics Theory · Mathematics 2026-05-06 Taehyun Kim

In this paper, we propose the family of Iterative Methods with Adaptive Thresholding (IMAT) for sparsity promoting reconstruction of Delta Modulated (DM) voice signals. We suggest a novel missing sampling approach to delta modulation that…

Information Theory · Computer Science 2020-02-11 Mahdi Boloursaz Mashhadi , Saber Malekmohammadi , Farokh Marvasti

Multimodal and multi-information microscopy techniques such as Fluorescence Lifetime Imaging Microscopy (FLIM) extend the informational channels beyond intensity-based fluorescence microscopy but suffer from reduced image quality due to…

Image and Video Processing · Electrical Eng. & Systems 2025-04-15 Hao Chen , Julian Najera , Dagmawit Geresu , Meenal Datta , Cody Smith , Scott Howard

In this paper, we propose a maximum smoothed likelihood method to estimate the component density functions of mixture models, in which the mixing proportions are known and may differ among observations. The proposed estimates maximize a…

Methodology · Statistics 2014-07-14 Tao Yu , Pengfei Li , Jing Qin