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Computational pathology is a field that has complemented various subspecialties of diagnostic pathology over the last few years. In this article a brief analyzis the different applications in nephrology is developed. To begin, an overview…

Image and Video Processing · Electrical Eng. & Systems 2022-10-20 Manuel Cossio

Mathematical models are increasingly a part of microbiological research. Here, we share our perspective on how modeling advances the discipline by: (i) enforcing logical consistency, (ii) enabling quantitative prediction, (iii) extracting…

Other Quantitative Biology · Quantitative Biology 2026-04-22 Jamie A. Lopez , Amir Erez

Mathematical modelling allows us to concisely describe fundamental principles in biology. Analysis of models can help to both explain known phenomena, and predict the existence of new, unseen behaviours. Model analysis is often a complex…

Quantitative Methods · Quantitative Biology 2020-08-13 Mark Blyth , Ludovic Renson , Lucia Marucci

High-fidelity modeling of blood flow is crucial for enhancing our understanding of cardiovascular disease. Despite significant advances in computational and experimental characterization of blood flow, the knowledge that we can acquire from…

Computational Physics · Physics 2021-06-08 Amirhossein Arzani , Scott T. M. Dawson

Decades of hardware, methodological, and algorithmic development have propelled molecular dynamics (MD) simulations to the forefront of materials-modeling techniques, bridging the gap between electronic-structure theory and continuum…

Soft Condensed Matter · Physics 2020-11-11 Tristan Bereau

In psychiatry, we often speak of constructing "models." Here we try to make sense of what such a claim might mean, starting with the most fundamental question: "What is (and isn't) a model?". We then discuss, in a concrete measurable sense,…

Neurons and Cognition · Quantitative Biology 2020-04-15 LR Mujica-Parodi , HH Strey

We need much better understanding of information processing and computation as its primary form. Future progress of new computational devices capable of dealing with problems of big data, internet of things, semantic web, cognitive robotics…

General Literature · Computer Science 2013-12-10 Mark Burgin , Gordana Dodig-Crnkovic

Computational chemistry allows researchers to experiment in sillico: by running a computer simulations of a biological or chemical processes of interest. Molecular dynamics with molecular mechanics model of interactions simulates N-body…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-03-03 Jana Pazúriková

Numerical model of the peripheral circulation and dynamical model of the large vessels and the heart are discussed in this paper. They combined together into the global model of blood circulation. Some results of numerical simulations…

Biological Physics · Physics 2007-12-31 S. S. Simakov , A. S. Kholodov , A. V. Evdokimov , Y. A. Kholodov

A variety of computational models have been developed to describe active matter at different length and time scales. The diversity of the methods and the challenges in modeling active matter---ranging from molecular motors and cytoskeletal…

Soft Condensed Matter · Physics 2020-04-21 M Reza Shaebani , Adam Wysocki , Roland G Winkler , Gerhard Gompper , Heiko Rieger

In this article, the notion of a mathematical model in science is attempted to be enlightened from several points of view. In particular, it is shown that mathematical models are introduced differently and used differently in different…

History and Overview · Mathematics 2022-05-25 Inge S. Helland

We present multiscale models of cancer tumor invasion with components at the molecular, cellular, and tissue levels. We provide biological justifications for the model components, present computational results from the model, and discuss…

Quantitative Methods · Quantitative Biology 2023-02-14 Bruce P. Ayati , Glenn F. Webb , Alexander R. A. Anderson

Computational modeling helps neuroscientists to integrate and explain experimental data obtained through neurophysiological and anatomical studies, thus providing a mechanism by which we can better understand and predict the principles of…

Neurons and Cognition · Quantitative Biology 2023-09-22 Parvin Zarei Eskikand , David B Grayden , Tatiana Kameneva , Anthony N Burkitt , Michael R Ibbotson

Powered by advanced information technology, more and more complex systems are exhibiting characteristics of the Cyber-Physical-Social Systems (CPSS). Understanding the mechanism of CPSS is essential to our ability to control their actions,…

Multiagent Systems · Computer Science 2022-03-01 Xiao Xue , Xiang-Ning Yu , De-Yu Zhou , Xiao Wang , Zhang-Bin Zhou , Fei-Yue Wang

Computational modeling and simulation have become essential tools in the quest to better understand the brain's makeup and to decipher the causal interrelations of its components. The breadth of biochemical and biophysical processes and…

Neurons and Cognition · Quantitative Biology 2019-06-10 Francesco Cremonesi , Felix Schürmann

Life, services and activities within cities have commonly been studied by separate disciplines, each one independent from the others. One such approach is the computer simulation, which enables in-depth modelling and cost-effective…

Physics and Society · Physics 2021-10-18 Irene Meta , Fernando M. Cucchietti , Diego Navarro , Eduardo Graells-Garrido , Vicente Guallart

Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essential tool for simulating biological systems and revealing…

Molecular Networks · Quantitative Biology 2024-08-13 Lingxia Qiao , Ali Khalilimeybodi , Nathaniel J Linden-Santangeli , Padmini Rangamani

Multi-modality cardiac imaging plays a key role in the management of patients with cardiovascular diseases. It allows a combination of complementary anatomical, morphological and functional information, increases diagnosis accuracy, and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Lei Li , Wangbin Ding , Liqun Huang , Xiahai Zhuang , Vicente Grau

Materials informatics offers a promising pathway towards rational materials design, replacing the current trial-and-error approach and accelerating the development of new functional materials. Through the use of sophisticated data analysis…

Materials Science · Physics 2018-05-17 Cormac Toher , Corey Oses , Stefano Curtarolo

Statistical mechanics is one of the most powerful and elegant tools in the quantitative sciences. One key virtue of statistical mechanics is that it is designed to examine large systems with many interacting degrees of freedom, providing a…

Quantitative Methods · Quantitative Biology 2007-08-15 Hernan G. Garcia , Jané Kondev , Nigel Orme , Julie A. Theriot , Rob Phillips