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Understanding the complexity of biological neural networks like the human brain is one of the scientific challenges of our century. The organization of the brain can be described at different levels, ranging from small neural networks to…

Neurons and Cognition · Quantitative Biology 2018-05-23 Stefano De Blasi

Computer modeling and simulation is used to analyze system behavior and evaluate strategies for operating in descriptive or predictive modes. In this part of the book, modeling and simulation approaches that have been proposed since the…

Multiagent Systems · Computer Science 2026-01-29 Serdar Abut

Computational fluid dynamics (CFD) has become a cornerstone of modern water engineering, providing quantitative tools for the analysis, prediction, and management of complex hydraulic systems across a wide range of spatial and temporal…

Fluid Dynamics · Physics 2025-12-19 Anshu Kumar , Kemi Olimba , Vyacheslav Kungurtsev , Fabio V. Difonzo

Simulation of post-prandial pharmacokinetics, such as muscle protein synthesis (MPS) through mTORC1 and insulin-induced glucose uptake, is often challenging due to the computational intensity of the multi-compartmental approach. In this…

Other Quantitative Biology · Quantitative Biology 2026-05-28 Alberto Calderone

Driving simulators have been used in the automotive industry for many years because of their ability to perform tests in a safe, reproducible and controlled immersive virtual environment. The improved performance of the simulator and its…

Robotics · Computer Science 2023-04-07 Akhil Chadha , Vishrut Jain , Andrea Michelle Rios Lazcano , Barys Shyrokau

This review examines the emerging role of mechanistic mathematical models based on continuum mechanics to address current challenges in glaucoma research. At present, the advent of Artificial Intelligence and data-based models have resulted…

Tissues and Organs · Quantitative Biology 2025-10-09 Daniel Sebastia-Saez , Jinyuan Luo , Mengqi Qin , Tao Chen , Cynthia Yu-Wai-Man

Simulation models are an absolute necessity in the human and social sciences, which can only very exceptionally use experimental science methods to construct their knowledge. Models enable the simulation of social processes by replacing the…

Computers and Society · Computer Science 2020-01-06 J. Raimbault , D. Pumain

Biological processes involve a variety of spatial and temporal scales. A holistic understanding of many biological processes therefore requires multi-scale models which capture the relevant properties on all these scales. In this manuscript…

Molecular Networks · Quantitative Biology 2015-06-23 Jan Hasenauer , Nick Jagiella , Sabrina Hross , Fabian J. Theis

Within the biological, physical, and social sciences, there are two broad quantitative traditions: statistical and mathematical modeling. Both traditions have the common pursuit of advancing our scientific knowledge, but these traditions…

Other Statistics · Statistics 2026-03-05 Paul N Zivich

The present level of development of molecular force field methods is assessed from the point of view of simulation-based engineering, outlining the immediate perspective for further development and highlighting the newly emerging discipline…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-05-22 Martin Horsch , Christoph Niethammer , Jadran Vrabec , Hans Hasse

Surgeons must accomplish complex technical and intellectual tasks that can generate unexpected and serious challenges with little or no room for error. In the last decade, computer simulations have played an increasing role in surgical…

Human-Computer Interaction · Computer Science 2019-03-12 Felix G. Hamza-Lup , Crenguta M. Bogdan , Dorin M. Popovici , Ovidiu D. Costea

The traditional methods of the biology, based on illustrative descriptions and linear logic explanations, are discussed. This work aims to improve this approach by introducing alternative tools to describe and represent complex biological…

Computational Engineering, Finance, and Science · Computer Science 2012-01-24 Alvaro Juan Ojeda Garcia

Mathematical models are an important tool for neuroscientists. During the last thirty years many papers have appeared on single neuron description and specifically on stochastic Integrate and Fire models. Analytical results have been proved…

Probability · Mathematics 2011-01-31 Laura Sacerdote , Maria Teresa Giraudo

PROTACs, as a highly promising new. therapeutic paradigm, have attracted widespread attention from the academic and pharmaceutical communities in recent years. To date, the design and validation of PROTACs molecule's druggability primarily…

Biomolecules · Quantitative Biology 2023-07-11 Mengman Wei

Computer models of cardiac electro-mechanics (EM) show promise as an effective means for quantitative analysis of clinical data and, potentially, for predicting therapeutic responses.realize such advanced applications methodological key…

Objectives: The main objective of this review article is to evaluate the usability of Computational Fluid Dynamics (CFD) as a supporting clinical tool for respiratory system. Data Source: The English articles referred for this review paper…

Fluid Dynamics · Physics 2023-10-24 Rajneesh Kashyap , R. Thundil Karuppa Raj

Qualitative modelling is a technique integrating the fields of theoretical computer science, artificial intelligence and the physical and biological sciences. The aim is to be able to model the behaviour of systems without estimating…

Computational Engineering, Finance, and Science · Computer Science 2012-09-19 Thomas W. Kelsey , Lars Kotthoff , Christoffer A. Jefferson , Stephen A. Linton , Ian Miguel , Peter Nightingale , Ian P. Gent

Simulations play important and diverse roles in statistical workflows, for example, in model specification, checking, validation, and even directly in model inference. Over the past decades, the application areas and overall potential of…

Computation · Statistics 2025-08-27 Paul-Christian Bürkner , Marvin Schmitt , Stefan T. Radev

Much of the research done by modern physicists would be impossible without the use of computation. And yet, while computation is a crucial tool of practicing physicists, physics curricula do not generally reflect its importance and utility.…

Physics Education · Physics 2015-06-15 Marcos D. Caballero , Steven J. Pollock

Microstructures, characterized by intricate structures at the microscopic scale, hold the promise of important disruptions in the field of mechanical engineering due to the superior mechanical properties they offer. One fundamental…

Computational Geometry · Computer Science 2024-11-26 Qiang Zou , Guoyue Luo
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