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The CLARITY method renders brains optically transparent to enable high-resolution imaging in the structurally intact brain. Anatomically annotating CLARITY brains is necessary for discovering which regions contain signals of interest.…

Quantitative Methods · Quantitative Biology 2016-05-09 Kwame S. Kutten , Joshua T. Vogelstein , Nicolas Charon , Li Ye , Karl Deisseroth , Michael I. Miller

Cytoarchitectonic maps provide microstructural reference parcellations of the brain, describing its organization in terms of the spatial arrangement of neuronal cell bodies as measured from histological tissue sections. Recent work provided…

Image and Video Processing · Electrical Eng. & Systems 2021-06-02 Christian Schiffer , Katrin Amunts , Stefan Harmeling , Timo Dickscheid

Purpose: Segmentation of organs-at-risk (OARs) is a bottleneck in current radiation oncology pipelines and is often time consuming and labor intensive. In this paper, we propose an atlas-based semi-supervised registration algorithm to…

Computer Vision and Pattern Recognition · Computer Science 2019-11-26 Charles Huang , Masoud Badiei , Hyunseok Seo , Ming Ma , Xiaokun Liang , Dante Capaldi , Michael Gensheimer , Lei Xing

Detection and segmentation of the hippocampal structures in volumetric brain images is a challenging problem in the area of medical imaging. In this paper, we propose a two-stage 3D fully convolutional neural network that efficiently…

Computer Vision and Pattern Recognition · Computer Science 2019-02-13 Dengsheng Chen , Wenxi Liu , You Huang , Tong Tong , Yuanlong Yu

This paper presents FeTal-SAM, a novel adaptation of the Segment Anything Model (SAM) tailored for fetal brain MRI segmentation. Traditional deep learning methods often require large annotated datasets for a fixed set of labels, making them…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Qi Zeng , Weide Liu , Bo Li , Ryne Didier , P. Ellen Grant , Davood Karimi

Automatic fetal brain tissue segmentation can enhance the quantitative assessment of brain development at this critical stage. Deep learning methods represent the state of the art in medical image segmentation and have also achieved…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Davood Karimi , Caitlin K. Rollins , Clemente Velasco-Annis , Abdelhakim Ouaalam , Ali Gholipour

Fetal Magnetic Resonance Imaging (MRI) is used in prenatal diagnosis and to assess early brain development. Accurate segmentation of the different brain tissues is a vital step in several brain analysis tasks, such as cortical surface…

Image and Video Processing · Electrical Eng. & Systems 2022-05-18 Liu Li , Qiang Ma , Matthew Sinclair , Antonios Makropoulos , Joseph Hajnal , A. David Edwards , Bernhard Kainz , Daniel Rueckert , Amir Alansary

Purpose: Widening the availability of fetal MRI with fully automatic real-time planning of radiological brain planes on 0.55T MRI. Methods: Deep learning-based detection of key brain landmarks on a whole-uterus EPI scan enables the…

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

This paper presents an annotated dataset of brain MRI images designed to advance the field of brain symmetry study. Magnetic resonance imaging (MRI) has gained interest in analyzing brain symmetry in neonatal infants, and challenges remain…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Arnaud Gucciardi , Safouane El Ghazouali , Francesca Venturini , Vida Groznik , Umberto Michelucci

Detecting brain lesions as abnormalities observed in magnetic resonance imaging (MRI) is essential for diagnosis and treatment. In the search of abnormalities, such as tumors and malformations, radiologists may benefit from computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Hassan Baker , Austin J. Brockmeier

Multi-spectral optoacoustic tomography (MSOT) is an emerging optical imaging method providing multiplex molecular and functional information from the rodent brain. It can be greatly augmented by magnetic resonance imaging (MRI) that offers…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Yexing Hu , Berkan Lafci , Artur Luzgin , Hao Wang , Jan Klohs , Xose Luis Dean-Ben , Ruiqing Ni , Daniel Razansky , Wuwei Ren

Accurate automatic tissue segmentation in fetal brain MRI is a crucial step in clinical diagnosis but remains challenging, particularly due to the dynamically changing anatomy and tissue contrast during fetal development. Existing…

Image and Video Processing · Electrical Eng. & Systems 2025-03-12 Haoan Xu , Tianshu Zheng , Xinyi Xu , Yao Shen , Jiwei Sun , Cong Sun , Guangbin Wang , Zhaopeng Cui , Dan Wu

Motion artifacts caused by prolonged acquisition time are a significant challenge in Magnetic Resonance Imaging (MRI), hindering accurate tissue segmentation. These artifacts appear as blurred images that mimic tissue-like appearances,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Sunyoung Jung , Yoonseok Choi , Mohammed A. Al-masni , Minyoung Jung , Dong-Hyun Kim

Registration of images with pathologies is challenging due to tissue appearance changes and missing correspondences caused by the pathologies. Moreover, mass effects as observed for brain tumors may displace tissue, creating larger…

Image and Video Processing · Electrical Eng. & Systems 2020-08-19 Xu Han , Zhengyang Shen , Zhenlin Xu , Spyridon Bakas , Hamed Akbari , Michel Bilello , Christos Davatzikos , Marc Niethammer

The lack of a comprehensive high-resolution atlas of the cerebellum has hampered studies of cerebellar involvement in normal brain function and disease. A good representation of the tightly foliated aspect of the cerebellar cortex is…

Image and Video Processing · Electrical Eng. & Systems 2023-05-30 Xuan Li , Paule-J Toussaint , Alan Evans , Xue Liu

In this paper, we introduce a Fast and Scalable Semi-supervised Multi-view Subspace Clustering (FSSMSC) method, a novel solution to the high computational complexity commonly found in existing approaches. FSSMSC features linear…

Machine Learning · Computer Science 2024-08-13 Huaming Ling , Chenglong Bao , Jiebo Song , Zuoqiang Shi

Joint registration of a stack of 2D histological sections to recover 3D structure (``3D histology reconstruction'') finds application in areas such as atlas building and validation of \emph{in vivo} imaging. Straightforward pairwise…

Image and Video Processing · Electrical Eng. & Systems 2021-12-02 Adrià Casamitjana , Marco Lorenzi , Sebastiano Ferraris , Loc Peter , Marc Modat , Allison Stevens , Bruce Fischl , Tom Vercauteren , Juan Eugenio Iglesias

In the realm of neuroscience, identifying distinctive patterns associated with neurological disorders via brain networks is crucial. Resting-state functional magnetic resonance imaging (fMRI) serves as a primary tool for mapping these…

Image and Video Processing · Electrical Eng. & Systems 2025-10-27 Jiaxing Xu , Mengcheng Lan , Xia Dong , Kai He , Wei Zhang , Qingtian Bian , Yiping Ke

Whole brain neuroanatomy using tera-voxel light-microscopic data sets is of much current interest. A fundamental problem in this field is the mapping of individual brain data sets to a reference space. Previous work has not rigorously…

Neurons and Cognition · Quantitative Biology 2019-04-18 Brian C. Lee , Meng Kuan Lin , Yan Fu , Junichi Hata , Michael I. Miller , Partha P. Mitra