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Several strategies have been developed recently to ensure valid inference after model selection; some of these are easy to compute, while others fare better in terms of inferential power. In this paper, we consider a selective inference…

Methodology · Statistics 2022-07-13 Snigdha Panigrahi , Jonathan Taylor

We consider the problem of parametric statistical inference when likelihood computations are prohibitively expensive but sampling from the model is possible. Several so-called likelihood-free methods have been developed to perform inference…

Machine Learning · Statistics 2020-09-14 Owen Thomas , Ritabrata Dutta , Jukka Corander , Samuel Kaski , Michael U. Gutmann

Growth in both size and complexity of modern data challenges the applicability of traditional likelihood-based inference. Composite likelihood (CL) methods address the difficulties related to model selection and computational intractability…

Statistics Theory · Mathematics 2017-09-12 Zhendong Huang , Davide Ferrari

Recent studies show that deep learning models achieve good performance on medical imaging tasks such as diagnosis prediction. Among the models, multimodality has been an emerging trend, integrating different forms of data such as chest…

Machine Learning · Computer Science 2022-02-10 Haodi Zhang , Chenyu Xu , Peirou Liang , Ke Duan , Hao Ren , Weibin Cheng , Kaishun Wu

One way to extract patterns from clinical records is to consider each patient record as a bag with various number of instances in the form of symptoms. Medical diagnosis is to discover informative ones first and then map them to one or more…

Machine Learning · Computer Science 2019-04-10 Zeyuan Wang , Josiah Poon , Shiding Sun , Simon Poon

Health-policy planning requires evidence on the burden that epidemics place on healthcare systems. Multiple, often dependent, datasets provide a noisy and fragmented signal from the unobserved epidemic process including transmission and…

Applications · Statistics 2024-09-11 Alice Corbella , Anne M Presanis , Paul J Birrell , Daniela De Angelis

Deep learning has been successful in predicting neurodegenerative disorders, such as Alzheimer's disease, from magnetic resonance imaging (MRI). Combining multiple imaging modalities, such as T1-weighted (T1) and diffusion-weighted imaging…

Artificial Intelligence · Computer Science 2026-01-30 Abhijith Shaji , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Greg Ver Steeg , Paul M. Thompson , Jose-Luis Ambite

We consider a general class of empirical-type likelihoods and develop higher order asymptotics with a view to characterizing members thereof that allow the existence of possibly data-dependent probability matching priors ensuring…

Statistics Theory · Mathematics 2008-12-18 Rahul Mukerjee

Machine learning is employed in healthcare to draw approximate conclusions regarding human diseases and mental health problems. Compared to older traditional methods, it can help to analyze data more efficiently and produce better and more…

Neurons and Cognition · Quantitative Biology 2023-05-25 Narges Ramesh , Yasmin Ghodsi , Hamidreza Bolhasani

Health data are often not symmetric to be adequately modeled through the usual normal distributions; most of them exhibit skewed patterns. They can indeed be modeled better through the larger family of skew-normal distributions covering…

Applications · Statistics 2019-09-24 Amarnath Nandy , Ayanendranath Basu , Abhik Ghosh

In rare disease physician targeting, a major challenge is how to identify physicians who are treating diagnosed or underdiagnosed rare diseases patients. Rare diseases have extremely low incidence rate. For a specified rare disease, only a…

Machine Learning · Statistics 2017-01-23 Yong Cai , Yunlong Wang , Dong Dai

Mild cognitive impairment (MCI) conversion prediction, i.e., identifying MCI patients of high risks converting to Alzheimer's disease (AD), is essential for preventing or slowing the progression of AD. Although previous studies have shown…

Image and Video Processing · Electrical Eng. & Systems 2021-09-27 Hao Guan , Chaoyue Wang , Dacheng Tao

Causal inference with observational studies often relies on the assumptions of unconfoundedness and overlap of covariate distributions in different treatment groups. The overlap assumption is violated when some units have propensity scores…

Methodology · Statistics 2022-07-19 Shu Yang , Peng Ding

This paper extends my research applying statistical decision theory to treatment choice with sample data, using maximum regret to evaluate the performance of treatment rules. The specific new contribution is to study as-if optimization…

Econometrics · Economics 2021-10-05 Charles F. Manski

Logistic regression models are a popular and effective method to predict the probability of categorical response data. However inference for these models can become computationally prohibitive for large datasets. Here we adapt ideas from…

Methodology · Statistics 2020-08-25 Tom Whitaker , Boris Beranger , Scott A. Sisson

The medical community believes binary medical event outcomes in EHR data contain sufficient information for making a sensible recommendation. However, there are two challenges to effectively utilizing such data: (1) modeling the…

Artificial Intelligence · Computer Science 2024-09-12 Xihao Piao , Pei Gao , Zheng Chen , Lingwei Zhu , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun

Randomization inference is a widely-used and appealing approach for analyzing treatment effects in randomized experiments, as it is finite-sample valid and does not require any distributional assumptions. However, naive application of…

Econometrics · Economics 2026-05-12 Xinran Li , Peizan Sheng , Zeyang Yu

The transition from mild cognitive impairment (MCI) to Alzheimer's disease (AD) is of great interest to clinical researchers. This phenomenon also serves as a valuable data source for quantitative methodological researchers developing new…

Applications · Statistics 2020-12-02 Zihuan Liu , Tapabrate Maiti , Andrew R. Bender

The key issues pertaining to collection of epidemic disease data for our analysis purposes are that it is a labour intensive, time consuming and expensive process resulting in availability of sparse sample data which we use to develop…

Machine Learning · Computer Science 2017-04-07 Terence Fusco , Yaxin Bi , Haiying Wang , Fiona Browne

Although there have been so many studies on schizophrenia under the framework of predictive coding, works focusing on treatment are very preliminary. A model-oriented, operationalist, and comprehensive understanding of schizophrenia would…

Neurons and Cognition · Quantitative Biology 2023-09-14 Lingyu Li , Chunbo Li