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In many neural systems anatomical motifs are present repeatedly, but despite their structural similarity they can serve very different tasks. A prime example for such a motif is the canonical microcircuit of six-layered neo-cortex, which is…

Neurons and Cognition · Quantitative Biology 2015-10-07 Michael Wibral , Viola Priesemann , Jim W. Kay , Joseph T. Lizier , William A. Phillips

A core feature of complex systems is that the interactions between elements in the present causally constrain each-other as the system evolves through time. To fully model all of these interactions (between elements, as well as ensembles of…

Neurons and Cognition · Quantitative Biology 2023-04-26 Thomas F. Varley

The Mutual Information (MI) is an often used measure of dependency between two random variables utilized in information theory, statistics and machine learning. Recently several MI estimators have been proposed that can achieve parametric…

Information Theory · Computer Science 2018-11-26 Morteza Noshad , Yu Zeng , Alfred O. Hero

Text-to-image generation and image captioning are recently emerged as a new experimental paradigm to assess machine intelligence. They predict continuous quantity accompanied by their sampling techniques in the generation, making evaluation…

Computer Vision and Pattern Recognition · Computer Science 2022-05-27 Jin-Hwa Kim , Yunji Kim , Jiyoung Lee , Kang Min Yoo , Sang-Woo Lee

In this work, we give efficient algorithms for privately estimating a Gaussian distribution in both pure and approximate differential privacy (DP) models with optimal dependence on the dimension in the sample complexity. In the pure DP…

Data Structures and Algorithms · Computer Science 2023-06-02 Daniel Alabi , Pravesh K. Kothari , Pranay Tankala , Prayaag Venkat , Fred Zhang

We consider the problem of inferring the conditional independence graph (CIG) of a multivariate stationary dicrete-time Gaussian random process based on a finite length observation. Using information-theoretic methods, we derive a lower…

Statistics Theory · Mathematics 2014-03-06 Gabor Hannak , Alexander Jung , Norbert Goertz

This article proposes a new method to estimate an existing mutual information based dependence measure using histogram density estimates. Finding a suitable bin length for histogram is an open problem. We propose a new way of computing the…

Information Theory · Computer Science 2015-09-15 Namita Jain , C. A. Murthy

We introduce the Mutual Information Machine (MIM), a probabilistic auto-encoder for learning joint distributions over observations and latent variables. MIM reflects three design principles: 1) low divergence, to encourage the encoder and…

Machine Learning · Computer Science 2020-02-24 Micha Livne , Kevin Swersky , David J. Fleet

We present an information-theoretic framework for discrete diffusion models that yields principled estimators of log-likelihood using score-matching losses. Inspired by the I-MMSE identity for the Gaussian setup, we derive analogous results…

Machine Learning · Computer Science 2025-10-29 Moongyu Jeon , Sangwoo Shin , Dongjae Jeon , Albert No

Computing expected information gain (EIG) from prior to posterior (equivalently, mutual information between candidate observations and model parameters or other quantities of interest) is a fundamental challenge in Bayesian optimal…

Methodology · Statistics 2026-01-30 Fengyi Li , Ricardo Baptista , Youssef Marzouk

We introduce a novel framework for decomposing interventional causal effects into synergistic, redundant, and unique components, building on the intuition of Partial Information Decomposition (PID) and the principle of M\"obius inversion.…

Artificial Intelligence · Computer Science 2025-09-22 Abel Jansma

We define the concept of dependence among multiple variables using maximum entropy techniques and introduce a graphical notation to denote the dependencies. Direct inference of information theoretic quantities from data uncovers…

Quantitative Methods · Quantitative Biology 2007-07-13 Ilya Nemenman

Gaussian graphical models are widely used to infer dependence structures. Bayesian methods are appealing to quantify uncertainty associated with structural learning, i.e., the plausibility of conditional independence statements given the…

Methodology · Statistics 2025-11-05 Deborah Sulem , Jack Jewson , David Rossell

Partial information decomposition (PID) partitions the information that a set of sources has about a target variable into synergistic, unique, and redundant contributions. This information-theoretic tool has recently attracted attention due…

Information Theory · Computer Science 2020-10-15 Abdullah Makkeh , Dirk Oliver Theis , Raul Vicente

In neural networks, task-relevant information is represented jointly by groups of neurons. However, the specific way in which this mutual information about the classification label is distributed among the individual neurons is not well…

Information Theory · Computer Science 2023-06-08 David A. Ehrlich , Andreas C. Schneider , Viola Priesemann , Michael Wibral , Abdullah Makkeh

Since its introduction in 2011, the partial information decomposition (PID) has triggered an explosion of interest in the field of multivariate information theory and the study of emergent, higher-order ("synergistic") interactions in…

Information Theory · Computer Science 2024-02-14 Thomas F. Varley

Spuriousness arises when there is an association between two or more variables in a dataset that are not causally related. In this work, we propose an explainability framework to preemptively disentangle the nature of such spurious…

Machine Learning · Computer Science 2025-11-17 Barproda Halder , Faisal Hamman , Pasan Dissanayake , Qiuyi Zhang , Ilia Sucholutsky , Sanghamitra Dutta

A reaction-coordinate--resolved information-theoretic analysis of chemical reactivity is developed using mutual information and partial information decomposition (PID). Along an intrinsic reaction coordinate (IRC), a local empirical…

Chemical Physics · Physics 2026-03-09 Kyunghoon Han , Miguel Gallegos

What are the distinct ways in which a set of predictor variables can provide information about a target variable? When does a variable provide unique information, when do variables share redundant information, and when do variables combine…

Information Theory · Computer Science 2018-05-04 Conor Finn , Joseph T Lizier

Chicharro (2017) introduced a procedure to determine multivariate partial information measures within the maximum entropy framework, separating unique, redundant, and synergistic components of information. Makkeh, Theis, and Vicente (2018)…

Computation · Statistics 2020-02-11 Abdullah Makkeh , Daniel Chicharro , Dirk Oliver Theis , Raul Vicente