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Estimating the angular separation between two incoherent thermal sources is a challenging task for direct imaging, especially when it is smaller than or comparable to the Rayleigh length. In addition, the task of discriminating whether…

Quantum Physics · Physics 2025-06-23 Ugo Zanforlin , Cosmo Lupo , Peter W. R. Connolly , Pieter Kok , Gerald S. Buller , Zixin Huang

Super-resolution localization microscopy is based on determining the positions of individual fluorescent markers in a sample. The major challenge in reaching an ever higher localization precision lies in the limited number of collected…

Optics · Physics 2020-08-05 Daniel Böning , Franz-Ferdinand Wieser , Vahid Sandoghdar

In the past years, optical fluorescence microscopy (OFM) made steady progress towards increasing the localisation precision of fluorescent emitters in biological samples. The high precision achieved by these techniques has prompted new…

We realize a scanning probe microscope using single trapped $^{87}$Rb atoms to measure optical fields with subwavelength spatial resolution. Our microscope operates by detecting fluorescence from a single atom driven by near-resonant light…

Atomic Physics · Physics 2022-03-02 Emma Deist , Justin A. Gerber , Yue-Hui Lu , Johannes Zeiher , Dan M. Stamper-Kurn

We present a quantum sensing protocol for the simultaneous estimation of the difference in the localization parameters of two single-photon sources, paving the way to single-photon 3D imaging and 3D nanoscopy beyond the diffraction limit.…

Quantum Physics · Physics 2026-02-18 Luca Maggio , Vincenzo Tamma

Aims. We investigate the maximum astrometric precision that can be reached on moving targets observed with digital-sensor arrays, and provide an estimate for its ultimate lower limit based on the Cram\'er-Rao bound. Methods. We extend…

Instrumentation and Methods for Astrophysics · Physics 2017-10-04 S. Bouquillon , R. A. Mendez , M. Altmann , T. Carlucci , C. Barache , F. Taris , A. H. Andrei , R. Smart

In this paper we explore the maximum precision attainable in the location of a point source imaged by a pixel array detector in the presence of a background, as a function of the detector properties. For this we use a well-known result from…

Instrumentation and Methods for Astrophysics · Physics 2015-06-15 Rene Mendez , Jorge Silva , Rodrigo Lobos

Only with the simultaneous estimation of multiple parameters are the quantum aspects of metrology fully revealed. This is due to the incompatibility of observables. The fundamental bound for multi-parameter quantum estimation is the Holevo…

Quantum Physics · Physics 2019-11-20 Francesco Albarelli , Jamie F. Friel , Animesh Datta

Already since the work by Abbe and Rayleigh the difficulty of super resolution where one wants to recover a collection of point sources from low-resolved microscopy measurements is thought to be dependent on whether the distance between the…

Numerical Analysis · Mathematics 2023-11-07 Mathias Hockmann

Multimode Gaussian quantum light, including multimode squeezed and/or multipartite quadrature entangled light, is a very general and powerful quantum resource with promising applications to quantum information processing and metrology…

Quantum Physics · Physics 2010-08-05 Olivier Pinel , Julien Fade , Nicolas Treps , Claude Fabre

Sensitivity limits are usually determined using the Cram\'er-Rao bound. Recently this approach has been used to obtain the ultimate resolution limit for the estimation of the separation between two incoherent point sources. However, methods…

Quantum Physics · Physics 2021-09-22 Giacomo Sorelli , Manuel Gessner , Mattia Walschaers , Nicolas Treps

We present novel lower bounds on the mean square error (MSE) of the location estimation of an emitting source via a network where the sensors are deployed randomly. The sensor locations are modeled as a homogenous Poisson point process. In…

Information Theory · Computer Science 2018-02-14 Itsik Bergel , Yair Noam

In location estimation, we are given $n$ samples from a known distribution $f$ shifted by an unknown translation $\lambda$, and want to estimate $\lambda$ as precisely as possible. Asymptotically, the maximum likelihood estimate achieves…

Statistics Theory · Mathematics 2023-02-07 Shivam Gupta , Jasper C. H. Lee , Eric Price

Various techniques have been developed to measure the 2D and 3D positions and 2D and 3D orientations of fluorescent molecules with improved precision over standard epifluorescence microscopes. Due to the challenging signal-to-background…

Optics · Physics 2021-02-02 Oumeng Zhang , Matthew D. Lew

The application of quantum estimation theory to the problem of imaging two incoherent point sources has recently led to new insights and better measurements for incoherent imaging and spectroscopy. To establish a more general limit beyond…

Quantum Physics · Physics 2019-01-09 Mankei Tsang

Biphoton frequency comb (BFC), which encompasses multiple discrete frequency modes and represents high-dimensional frequency entanglement, is crucial in quantum information processing due to its high information capacity and error…

Quantum Physics · Physics 2025-07-30 Baihong Li , Qi-qi Li , Boxin Yuan , Ruifang Dong , Shougang Zhang , Rui-Bo Jin

The Rayleigh diffraction limit imposes a fundamental restriction on the resolution of direct imaging systems, hindering the identification of incoherent optical sources, such as celestial bodies in astronomy and fluorophores in bioimaging.…

Quantum Physics · Physics 2025-12-12 Danilo Triggiani , Cosmo Lupo

Distributed aperture telescopes are a well-established approach for boosting resolution in astronomical imaging. However, theoretical limits on quantitative imaging precision, and the fundamentally best possible beam-combining and detection…

Quantum Physics · Physics 2024-03-15 Aqil Sajjad , Michael R Grace , Saikat Guha

Passive source localization is a well known inverse problem in which we convert the observed measurements into information about the direction of arrivals. In this paper we focus on the optimal resolution of such problem. More precisely, we…

Information Theory · Computer Science 2015-06-15 Rémy Boyer , Mohammed Nabil El Korso , Alexandre Renaux , Sylvie Marcos

We derive fundamental precision bounds for single-point axial localization. For the case of a Gaussian beam, this ultimate limit can be achieved with a single intensity scan, provided the camera is placed at one of two optimal transverse…

Quantum Physics · Physics 2019-10-14 J. Rehacek , M. Paur , B. Stoklasa , D. Koutny , Z. Hradil , L. L. Sanchez-Soto