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Exploratory analysis of time series data can yield a better understanding of complex dynamical systems. Granger causality is a practical framework for analysing interactions in sequential data, applied in a wide range of domains. In this…

Machine Learning · Computer Science 2021-01-20 Ričards Marcinkevičs , Julia E. Vogt

Granger causal inference is a contentious but widespread method used in fields ranging from economics to neuroscience. The original definition addresses the notion of causality in time series by establishing functional dependence…

Methodology · Statistics 2023-09-19 Noah D. Gade , Jordan Rodu

This paper is motivated by studies in neuroscience experiments to understand interactions between nodes in a brain network using different types of data modalities that capture different distinct facets of brain activity. To assess…

We consider the effects of correlations between the in- and out-degrees of individual neurons on the dynamics of a network of neurons. By using theta neurons, we can derive a set of coupled differential equations for the expected dynamics…

Adaptation and Self-Organizing Systems · Physics 2020-04-02 Carlo R. Laing , Christian Blasche

Functional connectome extends the anatomical connectome by capturing the relations between neurons according to their activity and interactions. When these relations are causal, the functional connectome maps how neural activity flows…

Neurons and Cognition · Quantitative Biology 2020-11-10 Rahul Biswas , Eli Shlizerman

We analyze a neural system which mimics a sensorial cortex, with different input characteristics, in presence of transmission delays. We propose a new measure to characterize collective behavior, based on the nonlinear extension of the…

Disordered Systems and Neural Networks · Physics 2015-06-25 Daniele Marinazzo , Mario Pellicoro , Sebastiano Stramaglia

The co-occurrence of action potentials of pairs of neurons within short time intervals is known since long. Such synchronous events can appear time-locked to the behavior of an animal and also theoretical considerations argue for a…

Neurons and Cognition · Quantitative Biology 2022-05-17 Moritz Helias , Tom Tetzlaff , Markus Diesmann

Estimating causal effects is crucial for decision-makers in many applications, but it is particularly challenging with observational network data due to peer interactions. Many algorithms have been proposed to estimate causal effects…

Artificial Intelligence · Computer Science 2024-09-16 Xiaojing Du , Jiuyong Li , Debo Cheng , Lin Liu , Wentao Gao , Xiongren Chen

The description of the dynamics of complex systems, in particular the capture of the interaction structure and causal relationships between elements of the system, is one of the central questions of interdisciplinary research. While the…

Machine Learning · Statistics 2025-04-30 Jakub Kořenek , Pavel Sanda , Jaroslav Hlinka

Advances in neural recording methods enable sampling from populations of thousands of neurons during the performance of behavioral tasks, raising the question of how recorded activity relates to the theoretical models of computations…

Neurons and Cognition · Quantitative Biology 2020-07-01 Audrey J. Sederberg , Ilya Nemenman

Human brain development is a complex and dynamic process that is affected by several factors such as genetics, sex hormones, and environmental changes. A number of recent studies on brain development have examined functional connectivity…

Computer Vision and Pattern Recognition · Computer Science 2020-01-29 Peyman Hosseinzadeh Kassani , Li Xiao , Gemeng Zhang , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu Ping Wang

Causal inference has traditionally focused on interventions at the unit level. In many applications, however, the central question concerns the causal effects of connections between units, such as transportation links, social relationships,…

Methodology · Statistics 2026-01-13 Shuli Chen , Jie Hu , Zhichao Jiang

Inferring synaptic connectivity from neural population activity is a fundamental challenge in computational neuroscience, complicated by partial observability and mismatches between inference models and true circuit dynamics. In this study,…

Neurons and Cognition · Quantitative Biology 2025-10-28 Kijung Yoon

We propose a novel framework for studying causal inference of gene interactions using a combination of compressive sensing and Granger causality techniques. The gist of the approach is to discover sparse linear dependencies between time…

Quantitative Methods · Quantitative Biology 2015-05-28 Mo Deng , Amin Emad , Olgica Milenkovic

We study Ising models for describing data and show that autoregressive methods may be used to learn their connections, also in the case of asymmetric connections and for multi-spin interactions. For each link the linear Granger causality is…

Neurons and Cognition · Quantitative Biology 2015-05-18 Mario Pellicoro , Sebastiano Stramaglia

The recent development of genetically encoded calcium indicators enables monitoring in vivo the activity of neuronal populations. Most analysis of these calcium transients relies on linear regression analysis based on the sensory stimulus…

Neurons and Cognition · Quantitative Biology 2014-09-10 Fabrizio De Vico Fallani , Martina Corazzol , Jenna R. Sternberg , Claire Wyart , Mario Chavez

Inferring causal relationships in observational time series data is an important task when interventions cannot be performed. Granger causality is a popular framework to infer potential causal mechanisms between different time series. The…

Machine Learning · Computer Science 2022-07-22 Zexuan Yin , Paolo Barucca

In many scenarios, human decisions are explained based on some high-level concepts. In this work, we take a step in the interpretability of neural networks by examining their internal representation or neuron's activations against concepts.…

Machine Learning · Computer Science 2021-11-09 Mohammad Nokhbeh Zaeem , Majid Komeili

Propagation of oscillatory signals through the cortex and coherence is shaped by the connectivity structure of neuronal circuits. This study systematically investigates the network and stimulus properties that shape network responses. The…

Neurons and Cognition · Quantitative Biology 2017-04-28 Hannah Bos , Jannis Schücker , Moritz Helias

Information flow provides a natural measure for the causal interaction between dynamical events. This study extends our previous rigorous formalism of componentwise information flow to the bulk information flow between two complex…

Neurons and Cognition · Quantitative Biology 2021-12-30 X. San Liang