English
Related papers

Related papers: SMAGEXP: a galaxy tool suite for transcriptomics d…

200 papers

Spatial transcriptomics is a modern sequencing technology that allows the measurement of the activity of thousands of genes in a tissue sample and map where the activity is occurring. This technology has enabled the study of the so-called…

Methodology · Statistics 2022-09-15 Andrea Sottosanti , Davide Risso

Syntax-guided synthesis is a paradigm in program synthesis in which the search space of candidate solutions is constrained by a syntactic template in the form of a grammar. These syntactic constraints serve two purposes: constraining the…

Software Engineering · Computer Science 2023-06-06 Yixuan Li , Federico Mora , Elizabeth Polgreen , Sanjit A. Seshia

Single-cell RNA sequencing (scRNA-seq) provides unprecedented insights into cellular heterogeneity, enabling detailed analysis of complex biological systems at single-cell resolution. However, the high dimensionality and technical noise…

Genomics · Quantitative Biology 2025-09-04 Hojjat Torabi Goudarzi , Maziyar Baran Pouyan

As gene expression measurement technology is shifting from microarrays to sequencing, the statistical tools available for their analysis must be adapted since RNA-seq data are measured as counts. Recently, it has been proposed to tackle the…

Applications · Statistics 2022-11-10 Denis Agniel , Boris P Hejblum

Advances in high-throughput sequencing technology have led to significant progress in measuring gene expressions at the single-cell level. The amount of publicly available single-cell RNA-seq (scRNA-seq) data is already surpassing 50M…

Machine Learning · Computer Science 2024-02-27 Jing Gong , Minsheng Hao , Xingyi Cheng , Xin Zeng , Chiming Liu , Jianzhu Ma , Xuegong Zhang , Taifeng Wang , Le Song

Analyzing the increasingly large volumes of data that are available today, possibly including the application of custom machine learning models, requires the utilization of distributed frameworks. This can result in serious productivity…

Databases · Computer Science 2019-08-20 Phanwadee Sinthong , Michael J. Carey

Metagenomics, the study of genome sequences of diverse organisms cohabiting in a shared environment, has experienced significant advancements across various medical and biological fields. Metagenomic analysis is crucial, for instance, in…

While scientists increasingly recognize the importance of metadata in describing their data, spreadsheets remain the preferred tool for supplying this information despite their limitations in ensuring compliance and quality. Various tools…

Digital Libraries · Computer Science 2023-12-15 Martin J. O'Connor , Marcos Martínez-Romero , Mete Ugur Akdogan , Josef Hardi , Mark A. Musen

As the first paper in a series on the study of the galaxy-galaxy lensing from Sloan Digital Sky Survey Data Release 7 (SDSS DR7), we present our image processing pipeline that corrects the systematics primarily introduced by the Point…

Cosmology and Nongalactic Astrophysics · Physics 2017-02-15 Wentao Luo , Xiaohu Yang , Jun Zhang , Dylan Tweed , Liping Fu , H. J. Mo , Frank C. van den Bosch , Chenggang Shu , Ran Li , Nan Li , Xiangkun Liu , Chuzhong Pan , Yiran Wang , Mario Radovich

This paper introduces the first open-source FPGA-based infrastructure, MetaSys, with a prototype in a RISC-V core, to enable the rapid implementation and evaluation of a wide range of cross-layer techniques in real hardware.…

We apply four statistical learning methods to a sample of $7941$ galaxies ($z<0.06$) from the Galaxy and Mass Assembly (GAMA) survey to test the feasibility of using automated algorithms to classify galaxies. Using $10$ features measured…

When performing an aggregate data meta-analysis of a continuous outcome, researchers often come across primary studies that report the sample median of the outcome. However, standard meta-analytic methods typically cannot be directly…

This work presents MeKDDaM-SAGA, computer-aided automation software for implementing a novel knowledge discovery and data mining process model that was designed for performing justifiable, traceable and reproducible metabolomics data…

Quantitative Methods · Quantitative Biology 2019-07-11 Ahmed BaniMustafa , Nigel Hardy

Microarrays are made it possible to simultaneously monitor the expression profiles of thousands of genes under various experimental conditions. It is used to identify the co-expressed genes in specific cells or tissues that are actively…

Machine Learning · Computer Science 2012-03-15 T. Chandrasekhar , K. Thangavel , E. Elayaraja

Molecular simulations are an important tool for research in physics, chemistry, and biology. The capabilities of simulations can be greatly expanded by providing access to advanced sampling methods and techniques that permit calculation of…

Synthetic data has emerged as a crucial solution to the data scarcity bottleneck in large language models (LLMs), particularly for specialized domains and low-resource languages. However, the broader adoption of existing synthetic data…

Machine Learning · Computer Science 2026-05-12 Zhichao Shi , Cehao Yang , Hao Zhou , Xiaojun Wu , Huajie Li , Xuhui Jiang , Chengjin Xu , Yuanzhuo Wang , Jian Guo

Methods: We have developed a software suite (DataSet Tracker) for real-time analysis designed to run on computers, smartphones, and smart glasses hardware and suitable for resource-constrained, on-the-fly computing in microscopes without…

Quantitative Methods · Quantitative Biology 2025-08-13 Alexandre Matov

Single-cell RNA sequencing (scRNA-seq) enables high-resolution analysis of cellular heterogeneity, but its complexity, which is marked by high dimensionality, sparsity, and batch effects, which poses major computational challenges.…

Computation and Language · Computer Science 2026-03-25 Cong Qi , Hanzhang Fang , Siqi Jiang , Xun Song , Tianxing Hu , Wei Zhi

The vast majority of connections between complex disease and common genetic variants were identified through meta-analysis, a powerful approach that enables large samples sizes while protecting against common artifacts due to population…

We present a dataset built for machine learning applications consisting of galaxy photometry, images, spectroscopic redshifts, and structural properties. This dataset comprises 286,401 galaxy images and photometry from the Hyper-Suprime-Cam…

Cosmology and Nongalactic Astrophysics · Physics 2024-10-02 Tuan Do , Bernie Boscoe , Evan Jones , Yun Qi Li , Kevin Alfaro