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Neuromorphic applications emulate the processing performed by the brain by using spikes as inputs instead of time-varying analog stimuli. Therefore, these time-varying stimuli have to be encoded into spikes, which can induce important…

Neural and Evolutionary Computing · Computer Science 2024-12-30 Ahmad El Ferdaoussi , Eric Plourde , Jean Rouat

In voltage imaging, where the membrane potentials of individual neurons are recorded at from hundreds to thousand frames per second using fluorescence microscopy, data processing presents a challenge. Even a fraction of a minute of…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Yosuke Bando , Ramdas Pillai , Atsushi Kajita , Farhan Abdul Hakeem , Yves Quemener , Hua-an Tseng , Kiryl D. Piatkevich , Changyang Linghu , Xue Han , Edward S. Boyden

Our knowledge of the sensory world is encoded by neurons in sequences of discrete, identical pulses termed action potentials or spikes. There is persistent controversy about the extent to which the precise timing of these spikes is relevant…

Neurons and Cognition · Quantitative Biology 2007-05-23 Ilya Nemenman , Geoffrey D. Lewen , William Bialek , Rob R. de Ruyter van Steveninck

Convolution is a central operation in Convolutional Neural Networks (CNNs), which applies a kernel to overlapping regions shifted across the image. However, because of the strong correlations in real-world image data, convolutional kernels…

Identification of patterns from discrete data time-series for statistical inference, threat detection, social opinion dynamics, brain activity prediction has received recent momentum. In addition to the huge data size, the associated…

Machine Learning · Computer Science 2019-02-22 Ruochen Yang , Gaurav Gupta , Paul Bogdan

The problem of super-resolution is concerned with the reconstruction of temporally/spatially localized events (or spikes) from samples of their convolution with a low-pass filter. Distinct from prior works which exploit sparsity in…

Signal Processing · Electrical Eng. & Systems 2023-03-06 Pulak Sarangi , Ryoma Hattori , Takaki Komiyama , Piya Pal

Coronary artery calcium (CAC) is a significant marker of atherosclerosis and cardiovascular events. In this work we present a system for the automatic quantification of calcium score in ECG-triggered non-contrast enhanced cardiac computed…

Computer Vision and Pattern Recognition · Computer Science 2017-10-10 G. Santini , D. Della Latta , N. Martini , G. Valvano , A. Gori , A. Ripoli , C. L. Susini , L. Landini , D. Chiappino

Radio astronomy is currently thriving with new large ground-based radio telescopes coming online in preparation for the upcoming Square Kilometre Array (SKA). Facilities like LOFAR, MeerKAT/SKA, ASKAP/SKA, and the future SKA-LOW bring…

Instrumentation and Methods for Astrophysics · Physics 2023-08-02 Benjamin Naoto Chiche , Julien N. Girard , Joana Frontera-Pons , Arnaud Woiselle , Jean-Luc Starck

Calcium imaging has emerged as a workhorse method in neuroscience to investigate patterns of neuronal activity. Instrumentation to acquire calcium imaging movies has rapidly progressed and has become standard across labs. Still, algorithms…

Quantitative Methods · Quantitative Biology 2019-06-03 Quico Spaen , Dorit S. Hochbaum , Roberto Asín-Achá

An optical flow gradient algorithm was applied to spontaneously forming net- works of neurons and glia in culture imaged by fluorescence optical microscopy in order to map functional calcium signaling with single pixel resolution. Optical…

Computational Engineering, Finance, and Science · Computer Science 2010-01-22 Marius Buibas , Diana Yu , Krystal Nizar , Gabriel A. Silva

Neuroprosthesis, as one type of precision medicine device, is aiming for manipulating neuronal signals of the brain in a closed-loop fashion, together with receiving stimulus from the environment and controlling some part of our brain/body.…

Neurons and Cognition · Quantitative Biology 2020-01-14 Zhaofei Yu , Jian K. Liu , Shanshan Jia , Yichen Zhang , Yajing Zheng , Yonghong Tian , Tiejun Huang

Much of studies on neural computation are based on network models of static neurons that produce analog output, despite the fact that information processing in the brain is predominantly carried out by dynamic neurons that produce discrete…

Neurons and Cognition · Quantitative Biology 2017-06-21 Dongsung Huh , Terrence J. Sejnowski

Flow-Imaging Microscopy (FIM) is commonly used in both academia and industry to characterize subvisible particles (those $\le 25 \mu m$ in size) in protein therapeutics. Pharmaceutical companies are required to record vast volumes of FIM…

Quantitative Methods · Quantitative Biology 2017-09-04 Christopher P. Calderon , Austin L. Daniels , Theodore W. Randolph

A novel energy-efficient edge computing paradigm is proposed for real-time deep learning-based image upsampling applications. State-of-the-art deep learning solutions for image upsampling are currently trained using either resize or…

Computer Vision and Pattern Recognition · Computer Science 2021-07-27 Ian Colbert , Ken Kreutz-Delgado , Srinjoy Das

Deep convolutional neural networks (CNNs) are the current state-of-the-art for digital analysis of histopathological images. The large size of whole-slide microscopy images (WSIs) requires advanced memory handling to read, display and…

Machine Learning · Computer Science 2020-11-13 André Pedersen , Marit Valla , Anna M. Bofin , Javier Pérez de Frutos , Ingerid Reinertsen , Erik Smistad

We report experimentally and in theory on the detection of edge information in digital images using ultrafast spiking optical artificial neurons towards convolutional neural networks (CNNs). In tandem with traditional convolution…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Joshua Robertson , Yahui Zhang , Matej Hejda , Andrew Adair , Julian Bueno , Shuiying Xiang , Antonio Hurtado

Reconstructing a sequence of sharp images from the blurry input is crucial for enhancing our insights into the captured scene and poses a significant challenge due to the limited temporal features embedded in the image. Spike cameras,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Kang Chen , Shiyan Chen , Jiyuan Zhang , Baoyue Zhang , Yajing Zheng , Tiejun Huang , Zhaofei Yu

In this paper, we consider linear state-space models with compressible innovations and convergent transition matrices in order to model spatiotemporally sparse transient events. We perform parameter and state estimation using a dynamic…

Machine Learning · Statistics 2016-10-21 Abbas Kazemipour , Ji Liu , Patrick Kanold , Min Wu , Behtash Babadi

Spiking neuronal networks are usually simulated with three main simulation schemes: the classical time-driven and event-driven schemes, and the more recent hybrid scheme. All three schemes evolve the state of a neuron through a series of…

Neurons and Cognition · Quantitative Biology 2018-01-24 Jeyashree Krishnan , PierGianLuca Porta Mana , Moritz Helias , Markus Diesmann , Edoardo Di Napoli

There is extensive evidence that biological neural networks encode information in the precise timing of the spikes generated and transmitted by neurons, which offers several advantages over rate-based codes. Here we adopt a vector space…

Neurons and Cognition · Quantitative Biology 2019-07-16 Dorian Florescu , Daniel Coca