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The rapid development of high-throughput technologies has enabled the generation of data from biological or disease processes that span multiple layers, like genomic, proteomic or metabolomic data, and further pertain to multiple sources,…

Machine Learning · Statistics 2022-01-25 Subhabrata Majumdar , George Michailidis

The cost of DNA sequencing has resulted in a surge of genetic data being utilised to improve scientific research, clinical procedures, and healthcare delivery in recent years. Since the human genome can uniquely identify an individual, this…

Cryptography and Security · Computer Science 2022-02-11 Sara Jafarbeiki , Raj Gaire , Amin Sakzad , Shabnam Kasra Kermanshahi , Ron Steinfeld

A genetic algorithm (GA) is a search method that optimises a population of solutions by simulating natural evolution. Good solutions reproduce together to create better candidates. The standard GA assumes that any two solutions can mate.…

Neural and Evolutionary Computing · Computer Science 2021-04-12 Aymeric Vie

Network medicine is an emerging area of research dealing with molecular and genetic interactions, network biomarkers of disease, and therapeutic target discovery. Large-scale biomedical data generation offers a unique opportunity to assess…

Molecular Networks · Quantitative Biology 2019-03-14 Abhijeet R. Sonawane , Scott T. Weiss , Kimberly Glass , Amitabh Sharma

Software-as-a-service (SaaS) is a type of software service delivery model which encompasses a broad range of business opportunities and challenges. Users and service providers are reluctant to integrate their business into SaaS due to its…

Cryptography and Security · Computer Science 2015-05-08 Pushpinder Kaur Chouhan , Feng Yao , Suleiman Y. Yerima , Sakir Sezer

The value of graph-based big data can be unlocked by exploring the topology and metrics of the networks they represent, and the computational approaches to this exploration take on many forms. The use-case of performing global computations…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-04-13 Miguel E. Coimbra , Alexandre P. Francisco , Luís Veiga

Generative Artificial Intelligence (GenAI) is taking the world by storm. It promises transformative opportunities for advancing and disrupting existing practices, including healthcare. From large language models (LLMs) for clinical note…

Artificial Intelligence · Computer Science 2025-10-29 Gang Chen , Changshuo Liu , Gene Anne Ooi , Marcus Tan , Zhongle Xie , Jianwei Yin , James Wei Luen Yip , Wenqiao Zhang , Jiaqi Zhu , Beng Chin Ooi

Data visualization is a fundamental tool in genomics research, enabling the exploration, interpretation, and communication of complex genomic features. While machine learning models show promise for transforming data into insightful…

Generative Adversarial Networks (GANs) and their extensions have carved open many exciting ways to tackle well known and challenging medical image analysis problems such as medical image de-noising, reconstruction, segmentation, data…

Computer Vision and Pattern Recognition · Computer Science 2019-10-10 Salome Kazeminia , Christoph Baur , Arjan Kuijper , Bram van Ginneken , Nassir Navab , Shadi Albarqouni , Anirban Mukhopadhyay

Multi-access Edge Computing (MEC) is booming as a promising paradigm to push the computation and communication resources from cloud to the network edge to provide services and to perform computations. With container technologies, mobile…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-20 Hailiang Zhao , Shuiguang Deng , Zijie Liu , Jianwei Yin , Schahram Dustdar

High-throughput sequencing (HTS) technologies have revolutionized the field of genomics, enabling rapid and cost-effective genome analysis for various applications. However, the increasing volume of genomic data generated by HTS…

Hardware Architecture · Computer Science 2023-06-01 Onur Mutlu , Can Firtina

Graphs may be used to represent many different problem domains -- a concrete example is that of detecting communities in social networks, which are represented as graphs. With big data and more sophisticated applications becoming widespread…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-04-03 Miguel E. Coimbra , Alexandre P. Francisco , Luis Veiga

The integration of Generative Artificial Intelligence (GenAI) within the Internet of Things (IoT) is garnering considerable interest. This growing attention stems from the continuous evolution and widespread adoption they are both having…

Artificial Intelligence · Computer Science 2025-04-11 Fabrizio Mangione , Claudio Savaglio , Giancarlo Fortino

Social networks may contain privacy-sensitive information about individuals. The objective of the network anonymization problem is to alter a given social network dataset such that the number of anonymous nodes in the social graph is…

Social and Information Networks · Computer Science 2026-01-16 Samuel Bonello , Rachel G. de Jong , Thomas H. W. Bäck , Frank W. Takes

In recent years, we have witnessed a dramatic data explosion in genomics, thanks to the improvement in sequencing technologies and the drastically decreasing costs. We are entering the era of millions of available genomes. Notably, each…

Other Quantitative Biology · Quantitative Biology 2018-03-28 Ka-Chun Wong

This paper describes a vision and work in progress to elevate network resources and data transfer management to the same level as compute and storage in the context of services access, scheduling, life cycle management, and orchestration.…

Networking and Internet Architecture · Computer Science 2022-03-22 Tom Lehman , Xi Yang , Chin Guok , Frank Wuerthwein , Igor Sfiligoi , John Graham , Aashay Arora , Dima Mishin , Diego Davila , Jonathan Guiang , Tom Hutton , Harvey Newman , Justas Balcas

With the reduction of sequencing costs and the pervasiveness of computing devices, genomic data collection is continually growing. However, data collection is highly fragmented and the data is still siloed across different repositories.…

Cryptography and Security · Computer Science 2022-03-14 Leonard Dervishi , Xinyue Wang , Wentao Li , Anisa Halimi , Jaideep Vaidya , Xiaoqian Jiang , Erman Ayday

Genotype networks are a method used in systems biology to study the "innovability" of a set of genotypes having the same phenotype. In the past they have been applied to determine the genetic heterogeneity, and stability to mutations, of…

Populations and Evolution · Quantitative Biology 2015-06-17 Giovanni Marco Dall'Olio , Jaume Bertranpetit , Andreas Wagner , Hafid Laayouni

HPC and Cloud have evolved independently, specializing their innovations into performance or productivity. Acceleration as a Service (XaaS) is a recipe to empower both fields with a shared execution platform that provides transparent access…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-10 Torsten Hoefler , Marcin Copik , Pete Beckman , Andrew Jones , Ian Foster , Manish Parashar , Daniel Reed , Matthias Troyer , Thomas Schulthess , Dan Ernst , Jack Dongarra

Sensing-as-a-service is anticipated to be the core feature of 6G perceptive mobile networks (PMN), where high-precision real-time sensing will become an inherent capability rather than being an auxiliary function as before. With the…

Signal Processing · Electrical Eng. & Systems 2023-11-09 Fuwang Dong , Fan Liu , Yuanhao Cui , Shihang Lu , Yunxin Li
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