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Multiple instance learning (MIL) is the preferred approach for whole slide image classification. However, most MIL approaches do not exploit the interdependencies of tiles extracted from a whole slide image, which could provide valuable…

Computer Vision and Pattern Recognition · Computer Science 2021-08-26 Marvin Lerousseau , Maria Vakalopoulou , Eric Deutsch , Nikos Paragios

Although multiple instance learning (MIL) methods are widely used for automatic tumor detection on whole slide images (WSI), they suffer from the extreme class imbalance within the small tumor WSIs. This occurs when the tumor comprises only…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Ziyu Su , Mostafa Rezapour , Usama Sajjad , Shuo Niu , Metin Nafi Gurcan , Muhammad Khalid Khan Niazi

Partial label learning (PLL) is a typical weakly supervised learning problem, where each training example is associated with a set of candidate labels among which only one is true. Most existing PLL approaches assume that the incorrect…

Machine Learning · Computer Science 2021-10-27 Ning Xu , Congyu Qiao , Xin Geng , Min-Ling Zhang

Histopathological whole slide image (WSI) analysis with deep learning has become a research focus in computational pathology. The current paradigm is mainly based on multiple instance learning (MIL), in which approaches with Transformer as…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hongbo Chu , Qiehe Sun , Jiawen Li , Yuxuan Chen , Lizhong Zhang , Tian Guan , Anjia Han , Yonghong He

We consider machine-learning-based thyroid-malignancy prediction from cytopathology whole-slide images (WSI). Multiple instance learning (MIL) approaches, typically used for the analysis of WSIs, divide the image (bag) into patches…

Learning from Label Proportions (LLP) is a weakly supervised learning method that aims to perform instance classification from training data consisting of pairs of bags containing multiple instances and the class label proportions within…

Machine Learning · Computer Science 2023-02-22 Ryoma Kobayashi , Yusuke Mukuta , Tatsuya Harada

With the increasing demand for histopathological specimen examination and diagnostic reporting, Multiple Instance Learning (MIL) has received heightened research focus as a viable solution for AI-centric diagnostic aid. Recently, to improve…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Sungrae Hong , Sol Lee , Jisu Shin , Jiwon Jeong , Mun Yong Yi

In many real-world tasks, particularly those involving data objects with complicated semantics such as images and texts, one object can be represented by multiple instances and simultaneously be associated with multiple labels. Such tasks…

Machine Learning · Computer Science 2020-07-07 Sheng-Jun Huang , Zhi-Hua Zhou

Automated disease diagnosis using medical image analysis relies on deep learning, often requiring large labeled datasets for supervised model training. Diseases like Acute Myeloid Leukemia (AML) pose challenges due to scarce and costly…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Salome Kazeminia , Max Joosten , Dragan Bosnacki , Carsten Marr

Weakly-supervised action localization aims to recognize and localize action instancese in untrimmed videos with only video-level labels. Most existing models rely on multiple instance learning(MIL), where the predictions of unlabeled…

Computer Vision and Pattern Recognition · Computer Science 2023-09-27 Guiqin Wang , Peng Zhao , Cong Zhao , Shusen Yang , Jie Cheng , Luziwei Leng , Jianxing Liao , Qinghai Guo

Multiple instance learning (MIL) has enabled substantial progress in computational histopathology, where a large amount of patches from gigapixel whole slide images are aggregated into slide-level predictions. Heatmaps are widely used to…

We introduce an extension of the multi-instance learning problem where examples are organized as nested bags of instances (e.g., a document could be represented as a bag of sentences, which in turn are bags of words). This framework can be…

Machine Learning · Computer Science 2020-10-06 Alessandro Tibo , Manfred Jaeger , Paolo Frasconi

Positive instance detection, especially for these in positive bags (true positive instances, TPIs), plays a key role for multiple instance learning (MIL) arising from a specific classification problem only provided with bag (a set of…

Computer Vision and Pattern Recognition · Computer Science 2016-12-13 Dongkuan Xu , Jia Wu , Wei Zhang , Yingjie Tian

Mixed-integer linear programming (MILP), a widely used modeling framework for combinatorial optimization, are central to many scientific and engineering applications, yet remains computationally challenging at scale. Recent advances in deep…

Artificial Intelligence · Computer Science 2026-01-09 Peixin Huang , Yaoxin Wu , Yining Ma , Cathy Wu , Wen Song , Wei Zhang

Quantification, variously called "supervised prevalence estimation" or "learning to quantify", is the supervised learning task of generating predictors of the relative frequencies (a.k.a. "prevalence values") of the classes of interest in…

Machine Learning · Computer Science 2022-11-16 Alejandro Moreo , Manuel Francisco , Fabrizio Sebastiani

Multi-instance partial-label learning (MIPL) is an emerging learning framework where each training sample is represented as a multi-instance bag associated with a candidate label set. Existing MIPL algorithms often overlook the margins for…

Machine Learning · Computer Science 2025-01-23 Wei Tang , Yin-Fang Yang , Zhaofei Wang , Weijia Zhang , Min-Ling Zhang

Despite the substantial progress of active learning for image recognition, there still lacks an instance-level active learning method specified for object detection. In this paper, we propose Multiple Instance Active Object Detection…

Computer Vision and Pattern Recognition · Computer Science 2021-04-07 Tianning Yuan , Fang Wan , Mengying Fu , Jianzhuang Liu , Songcen Xu , Xiangyang Ji , Qixiang Ye

Weakly-supervised temporal action localization aims to localize and recognize actions in untrimmed videos with only video-level category labels during training. Without instance-level annotations, most existing methods follow the…

Computer Vision and Pattern Recognition · Computer Science 2023-05-30 Huan Ren , Wenfei Yang , Tianzhu Zhang , Yongdong Zhang

Diagnosis and treatment of multiple pulmonary nodules are clinically important but challenging. Prior studies on nodule characterization use solitary-nodule approaches on multiple nodular patients, which ignores the relations between…

Image and Video Processing · Electrical Eng. & Systems 2020-07-09 Jiancheng Yang , Haoran Deng , Xiaoyang Huang , Bingbing Ni , Yi Xu

In the field of computational pathology, the use of decision support systems powered by state-of-the-art deep learning solutions has been hampered by the lack of large labeled datasets. Until recently, studies relied on datasets in the…

Computer Vision and Pattern Recognition · Computer Science 2018-10-01 Gabriele Campanella , Vitor Werneck Krauss Silva , Thomas J. Fuchs
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