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Related papers: MedTQ: Dynamic Topic Discovery and Query Generatio…

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Topic modeling seeks to uncover latent semantic structure in text corpora with minimal supervision. Neural approaches achieve strong performance but require extensive tuning and struggle with lifelong learning due to catastrophic forgetting…

Computation and Language · Computer Science 2026-04-20 Karthik Singaravadivelan , Anant Gupta , Zekun Wang , Christopher J. MacLellan

Semantic concepts and relations encoded in domain-specific ontologies and other medical semantic resources play a crucial role in deciphering terms in medical queries and documents. The exploitation of these resources for tackling the…

Information Retrieval · Computer Science 2020-05-19 Mohammed Maree , Israa Noor , Khaled Rabayah , Mohammed Belkhatir , Saadat M. Alhashmi

In pre-market drug safety review, grouping related adverse event terms into standardised MedDRA queries or the FDA Office of New Drugs Custom Medical Queries (OCMQs) is critical for signal detection. We present a novel quantitative…

Computation and Language · Computer Science 2025-12-09 Francois Vandenhende , Anna Georgiou , Michalis Georgiou , Theodoros Psaras , Ellie Karekla , Elena Hadjicosta

The widespread application of Artificial Intelligence (AI) techniques has significantly influenced the development of new therapeutic agents. These computational methods can be used to design and predict the properties of generated…

Neural and Evolutionary Computing · Computer Science 2024-08-21 Arthur Cerveira , Frederico Kremer , Darling de Andrade Lourenço , Ulisses B Corrêa

This thesis work falls within the framework of question answering (QA) in the biomedical domain where several specific challenges are addressed, such as specialized lexicons and terminologies, the types of treated questions, and the…

Computation and Language · Computer Science 2023-07-26 Mourad Sarrouti

With the rapid development of online medical platforms, consumer health questions (CHQs) are inefficient in diagnosis due to redundant information and frequent non-professional terms. The medical question summary (MQS) task aims to…

Computation and Language · Computer Science 2025-10-07 Chao Liu , Ling Luo , Tengxiao Lv , Huan Zhuang , Lejing Yu , Jian Wang , Hongfei Lin

Similar to managing software packages, managing the ontology life cycle involves multiple complex workflows such as preparing releases, continuous quality control checking, and dependency management. To manage these processes, a diverse set…

Automated generation of high-quality topical hierarchies for a text collection is a dream problem in knowledge engineering with many valuable applications. In this paper a scalable and robust algorithm is proposed for constructing a…

Machine Learning · Computer Science 2014-03-17 Chi Wang , Xueqing Liu , Yanglei Song , Jiawei Han

Biomedical Question Answering systems play a critical role in processing complex medical queries, yet they often struggle with the intricate nature of medical data and the demand for multi-hop reasoning. In this paper, we propose a model…

Computation and Language · Computer Science 2026-01-13 Quoc-An Nguyen , Thi-Minh-Thu Vu , Bich-Dat Nguyen , Dinh-Quang-Minh Tran , Hoang-Quynh Le

Objective: Human-curated disease ontologies are widely used for diagnostic evaluation, treatment and data comparisons over time, and clinical decision support. The classification principles underlying these ontologies are guided by the…

Molecular Networks · Quantitative Biology 2021-04-02 Giorgio Grani , Lorenzo Madeddu , Paola Velardi

Scientific machine learning research spans diverse domains and data modalities, yet existing benchmark efforts remain siloed and lack standardization. This makes novel and transformative applications of machine learning to critical…

The metadata about scientific experiments published in online repositories have been shown to suffer from a high degree of representational heterogeneity---there are often many ways to represent the same type of information, such as a…

Computation and Language · Computer Science 2020-12-17 Rafael S. Gonçalves , Maulik R. Kamdar , Mark A. Musen

Timely detection of critical health conditions remains a major challenge in public health analytics, especially in Big Data environments characterized by high volume, rapid velocity, and diverse variety of clinical data. This study presents…

Databases · Computer Science 2025-10-14 Ritesh Chandra , Sonali Agarwal , Navjot Singh

ChatGPT explores a strategic blueprint of question answering (QA) in delivering medical diagnosis, treatment recommendations, and other healthcare support. This is achieved through the increasing incorporation of medical domain data via…

Computation and Language · Computer Science 2024-01-23 Qing Li , Lei Li , Yu Li

Competency Questions (CQs) are a cornerstone of requirement elicitation in ontology engineering. CQs represent requirements as a set of natural language questions that an ontology should satisfy; they are traditionally modelled by ontology…

Artificial Intelligence · Computer Science 2026-04-20 Reham Alharbi , Valentina Tamma , Terry R. Payne , Jacopo de Berardinis

Biomedical researchers use ontologies to annotate their data with ontology terms, enabling better data integration and interoperability. However, the number, variety and complexity of current biomedical ontologies make it cumbersome for…

Artificial Intelligence · Computer Science 2017-06-09 Marcos Martinez-Romero , Clement Jonquet , Martin J. O'Connor , John Graybeal , Alejandro Pazos , Mark A. Musen

Keyword-based searches are today's standard in digital libraries. Yet, complex retrieval scenarios like in scientific knowledge bases, need more sophisticated access paths. Although each document somewhat contributes to a domain's body of…

Information Retrieval · Computer Science 2024-12-23 Hermann Kroll , Pascal Sackhoff , Timo Breuer , Ralf Schenkel , Wolf-Tilo Balke

Novel information retrieval methods to identify citations relevant to a clinical topic can overcome the knowledge gap existing between the primary literature (MEDLINE) and online clinical knowledge resources such as UpToDate. Searching the…

Computation and Language · Computer Science 2016-09-07 Kalpana Raja , Andrew J Sauer , Ravi P Garg , Melanie R Klerer , Siddhartha R Jonnalagadda

Motivation: The rapid growth of diverse biological data allows us to consider interactions between a variety of objects, such as genes, chemicals, molecular signatures, diseases, pathways and environmental exposures. Often, any pair of…

Machine Learning · Computer Science 2017-08-14 Marinka Zitnik , Blaz Zupan

Domain experts often rely on most recent knowledge for apprehending and disseminating specific biological processes that help them design strategies for developing prevention and therapeutic decision-making in various disease scenarios. A…

Computation and Language · Computer Science 2023-11-21 Md. Rezaul Karim , Lina Molinas Comet , Md Shajalal , Oya Deniz Beyan , Dietrich Rebholz-Schuhmann , Stefan Decker