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Ontology can be used for the interpretation of natural language. To construct an anti-infective drug ontology, one needs to design and deploy a methodological step to carry out the entity discovery and linking. Medical synonym resources…

Computation and Language · Computer Science 2018-12-06 Ying Shen , Yang Deng , Kaiqi Yuan , Li Liu , Yong Liu

In the expanding field of language model applications, medical knowledge representation remains a significant challenge due to the specialized nature of the domain. Large language models, such as GPT-4, obtain reasonable scores on medical…

Computation and Language · Computer Science 2024-05-24 Julien Khlaut , Corentin Dancette , Elodie Ferreres , Alaedine Bennani , Paul Hérent , Pierre Manceron

Question generation over knowledge bases (KBQG) aims at generating natural-language questions about a subgraph, i.e. a set of (connected) triples. Two main challenges still face the current crop of encoder-decoder-based methods, especially…

Computation and Language · Computer Science 2020-10-26 Sheng Bi , Xiya Cheng , Yuan-Fang Li , Yongzhen Wang , Guilin Qi

Medical image quality assessment (Med-IQA) is a prerequisite for clinical AI deployment, yet multimodal large language models (MLLMs) still fall substantially short of human experts, particularly when required to provide descriptive…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Jiyao Liu , Junzhi Ning , Wanying Qu , Lihao Liu , Chenglong Ma , Junjun He , Ningsheng Xu

With the exponential increase in online scientific literature, identifying reliable domain-specific data has become increasingly important but also very challenging. Manual data collection and filtering for domain-specific scientific…

Information Retrieval · Computer Science 2026-03-10 Nikita Gautam , Doina Caragea , Ignacio Ciampitti , Federico Gomez

High-throughput microarray and sequencing technology have been used to identify disease subtypes that could not be observed otherwise by using clinical variables alone. The classical unsupervised clustering strategy concerns primarily the…

Methodology · Statistics 2020-07-23 Peng Liu , Yusi Fang , Zhao Ren , Lu Tang , George C. Tseng

Real-world semantic or knowledge-based systems, e.g., in the biomedical domain, can become large and complex. Tool support for the localization and repair of faults within knowledge bases of such systems can therefore be essential for their…

Artificial Intelligence · Computer Science 2022-08-08 Patrick Rodler , Dietmar Jannach , Konstantin Schekotihin , Philipp Fleiss

As the number of scientific publications and preprints is growing exponentially, several attempts have been made to navigate this complex and increasingly detailed landscape. These have almost exclusively taken unsupervised approaches that…

This study aims to reveal what kind of topics emerged in the biomedical domain by retrospectively analyzing newly added MeSH (Medical Subject Headings) terms from 2001 to 2010 and how they have been used for indexing since their inclusion…

Digital Libraries · Computer Science 2021-09-15 Kun Lu , Guancan Yang , Xue Wang

Despite widespread applications of knowledge graphs (KGs) in various tasks such as question answering and intelligent conversational systems, existing KGs face two major challenges: information granularity and deficiency in timeliness.…

Artificial Intelligence · Computer Science 2024-05-01 Linyi Ding , Sizhe Zhou , Jinfeng Xiao , Jiawei Han

Personalized chronic care requires the integration of multimodal health data to enable precise, adaptive, and preventive decision-making. Yet most current digital twin (DT) applications remain organ-specific or tied to isolated data types,…

Software Engineering · Computer Science 2025-10-13 Amal Elgammal , Bernd J. Krämer , Michael P. Papazoglou , Mira Raheem

Enriching existing medical terminology knowledge bases (KBs) is an important and never-ending work for clinical research because new terminology alias may be continually added and standard terminologies may be newly renamed. In this paper,…

Computation and Language · Computer Science 2019-09-04 Jiaying Zhang , Zhixing Zhang , Huanhuan Zhang , Zhiyuan Ma , Yangming Zhou , Ping He

Multiple choice questions (MCQs) that can be generated from a domain ontology can significantly reduce human effort & time required for authoring & administering assessments in an e-Learning environment. Even though here are various methods…

Artificial Intelligence · Computer Science 2016-07-05 Vinu E. , Tahani Alsubait , P. Sreenivasa Kumar

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

Biomarker discovery is vital in advancing personalized medicine, offering insights into disease diagnosis, prognosis, and therapeutic efficacy. Traditionally, the identification and validation of biomarkers heavily depend on extensive…

Machine Learning · Computer Science 2024-09-25 Wangyang Ying , Dongjie Wang , Xuanming Hu , Ji Qiu , Jin Park , Yanjie Fu

Leveraging generative Artificial Intelligence (AI), we have transformed a dataset comprising 1,000 scientific papers into an ontological knowledge graph. Through an in-depth structural analysis, we have calculated node degrees, identified…

Machine Learning · Computer Science 2024-06-12 Markus J. Buehler

Currently, Medical Subject Headings (MeSH) are manually assigned to every biomedical article published and subsequently recorded in the PubMed database to facilitate retrieving relevant information. With the rapid growth of the PubMed…

Computation and Language · Computer Science 2022-03-15 Xindi Wang , Robert E. Mercer , Frank Rudzicz

Using natural language processing (NLP) technologies to develop medical chatbots makes the diagnosis of the patient more convenient and efficient, which is a typical application in healthcare AI. Because of its importance, lots of research…

Computation and Language · Computer Science 2023-12-06 Ke Liang , Sifan Wu , Jiayi Gu

The Medical Subject Headings (MeSH), one of the main knowledge organization systems in the biomedical domain, continuously evolves to reflect the latest scientific discoveries in health and life sciences. Previous research has focused on…

Social and Information Networks · Computer Science 2025-10-09 Jenny Copara , Nona Naderi , Gilles Falquet , Douglas Teodoro

A main challenge of data-driven sciences is how to make maximal use of the progressively expanding databases of experimental datasets in order to keep research cumulative. We introduce the idea of a modeling-based dataset retrieval engine…

Quantitative Methods · Quantitative Biology 2015-06-19 Ali Faisal , Jaakko Peltonen , Elisabeth Georgii , Johan Rung , Samuel Kaski
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