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Many events in the vertebrate immune system are influenced by some element of chance. The objective of the present work is to describe affinity maturation of B lymphocytes (in which random events are perhaps the most characteristic), and to…

Molecular Networks · Quantitative Biology 2015-05-05 Tamás Szabados , Gábor Tusnády , László Varga , Tibor Bakács

In this paper, we study the dynamics of epidemic processes taking place in temporal and adaptive networks. Building on the activity-driven network model, we propose an adaptive model of epidemic processes, where the network topology…

Social and Information Networks · Computer Science 2018-02-27 Masaki Ogura , Victor M. Preciado , Naoki Masuda

We analyze the dynamics of a population of independent random walkers on a graph and develop a simple model of epidemic spreading. We assume that each walker visits independently the nodes of a finite ergodic graph in a discrete-time…

Physics and Society · Physics 2021-01-19 Michael Bestehorn , Alejandro P. Riascos , Thomas M. Michelitsch , Bernard A. Collet

A susceptible-infected-susceptible (SIS) model of multiple contagions on multilayer networks is developed to incorporate different spreading channels and disease mutations. The basic reproduction number for this model is estimated…

Physics and Society · Physics 2020-03-31 Petar Jovanovski , Igor Tomovski , Ljupco Kocarev

We investigate a model for spatial epidemics explicitly taking into account bi-directional movements between base and destination locations on individual mobility networks. We provide a systematic analysis of generic dynamical features of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

The current survey paper concerns stochastic mathematical models for the spread of infectious diseases. It starts with the simplest setting of a homogeneous population in which a transmittable disease spreads during a short outbreak.…

Applications · Statistics 2018-01-30 Tom Britton

The spread of ideas across a social network can be studied using complex contagion models, in which agents are activated by contact with multiple activated neighbors. The investigation of complex contagions can provide crucial insights into…

Social and Information Networks · Computer Science 2015-03-19 Sergey Melnik , Jonathan A. Ward , James P. Gleeson , Mason A. Porter

Mathematical models of infectious diseases, which are in principle analytically tractable, use two general approaches. The first approach, generally known as compartmental modeling, addresses the time evolution of disease propagation at the…

Populations and Evolution · Quantitative Biology 2010-09-16 Pierre-André Noël , Bahman Davoudi , Robert C. Brunham , Louis J. Dubé , Babak Pourbohloul

In contrast to previous common wisdom that epidemic activity in heterogeneous networks is dominated by the hubs with the largest number of connections, recent research has pointed out the role that the innermost, dense core of the network…

Physics and Society · Physics 2012-05-04 Claudio Castellano , Romualdo Pastor-Satorras

Antibodies and humoral memory are key components of the adaptive immune system. We consider and computationally model mechanisms by which humoral memory present at baseline might instead increase infection load; we refer to this effect as…

Cell Behavior · Quantitative Biology 2023-02-16 Ariel Nikas , Hasan Ahmed , Mia R. Moore , Veronika I. Zarnitsyna , Rustom Antia

Many network contagion processes are inherently multiplex in nature, yet are often reduced to processes on uniplex networks in analytic practice. We therefore examine how data modeling choices can affect the predictions of contagion…

Physics and Society · Physics 2023-01-24 Nicholas W. Landry , jimi adams

The spread of certain diseases can be promoted, in some cases substantially, by prior infection with another disease. One example is that of HIV, whose immunosuppressant effects significantly increase the chances of infection with other…

Physics and Society · Physics 2014-08-04 M. E. J. Newman , C. R. Ferrario

The simultaneous emergence of several abrupt disease outbreaks or the extinction of some serotypes of multi-strain diseases are fingerprints of the interaction between pathogens spreading within the same population. Here, we propose a…

Physics and Society · Physics 2019-12-25 David Soriano-Paños , Fakhteh Ghanbarnejad , Sandro Meloni , Jesús Gómez-Gardeñes

We developed a mathematical model to investigate the role of indirect transmission in the spread of infectious diseases, using the illustrative example of sarcoptic mange as a case study. This disease can be transmitted through direct…

Populations and Evolution · Quantitative Biology 2024-07-19 Tomás Ignacio González , María Fabiana Laguna , Guillermo Abramson

Records of social interactions provide us with new sources of data for understanding how interaction patterns affect collective dynamics. Such human activity patterns are often bursty, i.e., they consist of short periods of intense activity…

Physics and Society · Physics 2015-06-05 Taro Takaguchi , Naoki Masuda , Petter Holme

can evolve simultaneously. For the information-driven adaptive process, susceptible (infected) individuals who have abilities to recognize the disease would break the links of their infected (susceptible) neighbors to prevent the epidemic…

Physics and Society · Physics 2015-05-20 Xiu-Xiu Zhan , Chuang Liu , Gui-Quan Sun , Zi-Ke Zhang

We study a stochastic epidemic model with multiple patches (locations), where individuals in each patch are categorized into three compartments, Susceptible, Infected and Recovered/Removed, and may migrate from one patch to another in any…

Probability · Mathematics 2023-08-21 Guodong Pang , Etienne Pardoux

Most spreading processes require spatial proximity between agents. The stationary state of spreading dynamics in a population of mobile agents thus depends on the interplay between the time and length scales involved in the epidemic process…

Statistical Mechanics · Physics 2024-03-05 Jorge P. Rodríguez , Matteo Paoluzzi , Demian Levis , Michele Starnini

Host mobility plays a fundamental role in the spatial spread of infectious diseases. Previous theoretical works based on the integration of network theory into the metapopulation framework have shown that the heterogeneities that…

Physics and Society · Physics 2013-09-26 Chiara Poletto , Michele Tizzoni , Vittoria Colizza

Deterministic compartmental models have been used extensively in modeling epidemic propagation. These models are required to fit available data and numerical procedures are often implemented to this end. But not every model architecture is…

Populations and Evolution · Quantitative Biology 2021-11-23 Gabriel Turinici