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Dementia is a collection of symptoms associated with impaired cognition and impedes everyday normal functioning. Dementia, with Alzheimer's disease constituting its most common type, is highly complex in terms of etiology and…

Dementia is a neurodegenerative disease that causes gradual cognitive impairment, which is very common in the world and undergoes a lot of research every year to prevent and cure it. It severely impacts the patient's ability to remember…

As the number of dementia patients rises, the need for accurate diagnostic procedures rises as well. Current methods, like using an MRI scan, rely on human input, which can be inaccurate. However, the decision logic behind machine learning…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Tyler Morris , Ziming Liu , Longjian Liu , Xiaopeng Zhao

Stochastic gradient MCMC (SG-MCMC) algorithms have proven useful in scaling Bayesian inference to large datasets under an assumption of i.i.d data. We instead develop an SG-MCMC algorithm to learn the parameters of hidden Markov models…

Machine Learning · Statistics 2017-06-16 Yi-An Ma , Nicholas J. Foti , Emily B. Fox

We propose a Bayesian nonparametric mixture model for prediction- and information extraction tasks with an efficient inference scheme. It models categorical-valued time series that exhibit dynamics from multiple underlying patterns (e.g.…

Machine Learning · Statistics 2017-06-21 Jan Reubold , Thorsten Strufe , Ulf Brefeld

Hidden Markov models (HMMs) and their extensions have proven to be powerful tools for classification of observations that stem from systems with temporal dependence as they take into account that observations close in time are likely…

Applications · Statistics 2021-11-22 Sofia Ruiz-Suarez , Vianey Leos-Barajas , Juan Manuel Morales

This paper presents a new and flexible prognostics framework based on a higher order hidden semi-Markov model (HOHSMM) for systems or components with unobservable health states and complex transition dynamics. The HOHSMM extends the basic…

Applications · Statistics 2020-02-14 Ying Liao , Yisha Xiang , Min Wang

The ageing population trend is correlated with an increased prevalence of acquired cognitive impairments such as dementia. Although there is no cure for dementia, a timely diagnosis helps in obtaining necessary support and appropriate…

Computer Vision and Pattern Recognition · Computer Science 2021-01-06 Xing Liang , Anastassia Angelopoulou , Epaminondas Kapetanios , Bencie Woll , Reda Al-batat , Tyron Woolfe

Hidden Markov models and their variants are the predominant sequential classification method in such domains as speech recognition, bioinformatics and natural language processing. Being generative rather than discriminative models, however,…

Machine Learning · Statistics 2013-02-18 John A. Quinn , Masashi Sugiyama

This work studies networked agents cooperating to track a dynamical state of nature under partial information. The proposed algorithm is a distributed Bayesian filtering algorithm for finite-state hidden Markov models (HMMs). It can be used…

Signal Processing · Electrical Eng. & Systems 2022-12-07 Mert Kayaalp , Virginia Bordignon , Stefan Vlaski , Vincenzo Matta , Ali H. Sayed

This work attempts to approximate a linear Gaussian system with a finite-state hidden Markov model (HMM), which is found useful in solving sophisticated event-based state estimation problems. An indirect modeling approach is developed,…

Systems and Control · Electrical Eng. & Systems 2020-07-10 Kaikai Zheng , Dawei Shi , Ling Shi

Eye Movement analysis with Hidden Markov Models (EMHMM) is a method for modeling eye fixation sequences using hidden Markov models (HMMs). In this report, we run a simulation study to investigate the estimation error for learning HMMs with…

Machine Learning · Statistics 2019-06-26 Antoni B. Chan , Janet H. Hsiao

Recent studies on modelling the progression of Alzheimer's disease use a single modality for their predictions while ignoring the time dimension. However, the nature of patient data is heterogeneous and time dependent which requires models…

Computers and Society · Computer Science 2021-10-19 Sofia Lahrichi , Maryem Rhanoui , Mounia Mikram , Bouchra El Asri

In a clinical trial of a treatment for alcoholism, a common response variable of interest is the number of alcoholic drinks consumed by each subject each day, or an ordinal version of this response, with levels corresponding to abstinence,…

Applications · Statistics 2010-10-08 Kenneth E. Shirley , Dylan S. Small , Kevin G. Lynch , Stephen A. Maisto , David W. Oslin

Alzheimers disease is a deadly neurological condition, impairing important memory and brain functions. Alzheimers disease promotes brain shrinkage, ultimately leading to dementia. Dementia diagnosis typically takes 2.8 to 4.4 years after…

The hidden Markov model (HMM) provides a powerful framework for inference in time-varying environments, where the underlying state evolves according to a Markov chain. To address the optimal filtering problem in general dynamic settings, we…

Systems and Control · Electrical Eng. & Systems 2025-06-10 Dongyan Sui , Haotian Pu , Siyang Leng , Stefan Vlaski

The hidden Markov model (HMM) is a generative model that treats sequential data under the assumption that each observation is conditioned on the state of a discrete hidden variable that evolves in time as a Markov chain. In this paper, we…

Artificial Intelligence · Computer Science 2011-09-07 Emanuele Coviello , Antoni B. Chan , Gert R. G. Lanckriet

Objective Alzheimer disease (AD) is the most common cause of dementia, a syndrome characterized by cognitive impairment severe enough to interfere with activities of daily life. We aimed to conduct a systematic literature review (SLR) of…

Quantitative Methods · Quantitative Biology 2021-08-31 Sayantan Kumar , Inez Oh , Suzanne Schindler , Albert M Lai , Philip R O Payne , Aditi Gupta

Hidden Markov model (HMM) has been successfully used for sequential data modeling problems. In this work, we propose to power the modeling capacity of HMM by bringing in neural network based generative models. The proposed model is termed…

Machine Learning · Computer Science 2020-05-26 Dong Liu , Antoine Honoré , Saikat Chatterjee , Lars K. Rasmussen

In medicine, comorbidities refer to the presence of multiple, co-occurring diseases. Due to their co-occurring nature, the course of one comorbidity is often highly dependent on the course of the other disease and, hence, treatments can…

Applications · Statistics 2021-03-16 Basil Maag , Stefan Feuerriegel , Mathias Kraus , Maytal Saar-Tsechansky , Thomas Züger