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Stochastic fluctuations of molecule numbers are ubiquitous in biological systems. Important examples include gene expression and enzymatic processes in living cells. Such systems are typically modelled as chemical reaction networks whose…

Quantitative Methods · Quantitative Biology 2017-01-13 David Schnoerr , Guido Sanguinetti , Ramon Grima

Boolean network models of strongly connected modules are capable of capturing the high regulatory complexity of many biological gene regulatory circuits. We study numerically the previously introduced basin entropy, a parameter for the…

Disordered Systems and Neural Networks · Physics 2009-11-13 P. Krawitz , I. Shmulevich

The rate of entropy production by a stochastic process quantifies how far it is from thermodynamic equilibrium. Equivalently, entropy production captures the degree to which detailed balance and time-reversal symmetry are broken. Despite…

Statistical Mechanics · Physics 2020-12-02 Luca Cocconi , Rosalba Garcia-Millan , Zigan Zhen , Bianca Buturca , Gunnar Pruessner

We define the concept of dependence among multiple variables using maximum entropy techniques and introduce a graphical notation to denote the dependencies. Direct inference of information theoretic quantities from data uncovers…

Quantitative Methods · Quantitative Biology 2007-07-13 Ilya Nemenman

This paper deals with the asymptotic behavior and FEM error analysis of a class of strongly damped wave equations using a semidiscrete finite element method in spatial directions combined with a finite difference scheme in the time…

Numerical Analysis · Mathematics 2025-11-03 Krishan Kumar , P. Danumjaya , Anil Kumar , Amiya K. Pani

Understanding the non-equilibrium dynamics of extended quantum systems after the trigger of a sudden, global perturbation (quench) represents a daunting challenge, especially in the presence of interactions. The main difficulties stem from…

Strongly Correlated Electrons · Physics 2009-11-13 Alexandre Faribault , Pasquale Calabrese , Jean-Sebastien Caux

Exponential random graph models (ERGMs) are a widely used framework for network data, enabling hypothesis testing on the structural mechanisms underlying observed networks. Bayesian ERGMs provide principled uncertainty quantification and…

Methodology · Statistics 2026-05-26 Alberto Caimo , Isabella Gollini

Problems of probabilistic inference and decision making under uncertainty commonly involve continuous random variables. Often these are discretized to a few points, to simplify assessments and computations. An alternative approximation is…

Artificial Intelligence · Computer Science 2013-03-08 William B. Poland , Ross D. Shachter

We investigate a Poisson-Nernst-Planck type system in three spatial dimensions where the strength of the electric drift depends on a possibly small parameter and the particles are assumed to diffuse quadratically. On grounds of the global…

Analysis of PDEs · Mathematics 2015-10-23 Jonathan Zinsl

In this paper, we consider diagonal hyperbolic systems with monotone continuous initial data. We propose a natural semi-explicit and upwind first order scheme. Under a certain non-negativity condition on the Jacobian matrix of the…

Numerical Analysis · Mathematics 2016-12-01 Laurent Monasse , Régis Monneau

Bayesian inference for exponential family random graph models (ERGMs) is a doubly-intractable problem because of the intractability of both the likelihood and posterior normalizing factor. Auxiliary variable based Markov Chain Monte Carlo…

Computation · Statistics 2020-07-15 Fan Yin , Carter T. Butts

We consider the problem of estimating a probability distribution that maximizes the entropy while satisfying a finite number of moment constraints, possibly corrupted by noise. Based on duality of convex programming, we present a novel…

Optimization and Control · Mathematics 2019-10-22 Tobias Sutter , David Sutter , Peyman Mohajerin Esfahani , John Lygeros

We report multipronged progress on the stochastic averaging approach to numerical analytic continuation of quantum Monte Carlo data. With the sampled spectrum parametrized with delta-functions in continuous frequency space, a calculation of…

Strongly Correlated Electrons · Physics 2023-01-11 Hui Shao , Anders W. Sandvik

We consider a model system consisting of two reaction-diffusion equations, where one species diffuses in a volume while the other species diffuses on the surface which surrounds the volume. The two equations are coupled via a nonlinear…

Analysis of PDEs · Mathematics 2017-07-21 Tang Quoc Bao , Klemens Fellner , Evangelos Latos

We study the exponential stability of evolutionary equations. The focus is laid on second order problems and we provide a way to rewrite them as a suitable first order evolutionary equation, for which the stability can be proved by using…

Analysis of PDEs · Mathematics 2015-05-11 Sascha Trostorff

Systems with long-range interactions display a short-time relaxation towards Quasi Stationary States (QSS) whose lifetime increases with the system size. In the paradigmatic Hamiltonian Mean-field Model (HMF) out-of-equilibrium phase…

Statistical Mechanics · Physics 2016-02-15 Gabriele Martelloni , Gianluca Martelloni , Pierre de Buyl , Duccio Fanelli

We consider a damped linear hyperbolic system modelling the propagation of pressure waves in a network of pipes. Well-posedness is established via semi-group theory and the existence of a unique steady state is proven in the absence of…

Numerical Analysis · Mathematics 2016-05-11 Herbert Egger , Thomas Kugler

We characterize different cell states, related to cancer and ageing phenotypes, by a measure of entropy of network ensembles, integrating gene expression values and protein interaction networks. The entropy measure estimates the parameter…

Molecular Networks · Quantitative Biology 2013-05-24 G. Menichetti , G. Bianconi , E. Giampieri , G. Castellani , D. Remondini

Aussel et al. (J Optim Theory Appl 170 818-837 2016) introduced the concept of projected solutions for the quasi-variational inequalities with a non-self constraint map, that is, the case where the constraint map may take values outside the…

Optimization and Control · Mathematics 2025-06-30 Didier Aussel , Jauny , Asrifa Sultana , Shivani Valecha

We consider the one-dimensional $XX$-model in a quasi-periodic transverse-field described by the Harper potential, which is equivalent to a tight-binding model of spinless fermions with a quasi-periodic chemical potential. For weak…

Disordered Systems and Neural Networks · Physics 2014-11-26 Gergö Roósz , Uma Divakaran , Heiko Rieger , Ferenc Iglói
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