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Histopathological image classification is an important task in medical image analysis. Recent approaches generally rely on weakly supervised learning due to the ease of acquiring case-level labels from pathology reports. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Bodong Zhang , Hamid Manoochehri , Man Minh Ho , Fahimeh Fooladgar , Yosep Chong , Beatrice S. Knudsen , Deepika Sirohi , Tolga Tasdizen

Recent advances in whole-slide image (WSI) scanners and computational capabilities have significantly propelled the application of artificial intelligence in histopathology slide analysis. While these strides are promising, current…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Weiyi Wu , Chongyang Gao , Joseph DiPalma , Soroush Vosoughi , Saeed Hassanpour

Semi-supervised learning (SSL), which aims at leveraging a few labeled images and a large number of unlabeled images for network training, is beneficial for relieving the burden of data annotation in medical image segmentation. According to…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Xinkai Zhao , Chaowei Fang , De-Jun Fan , Xutao Lin , Feng Gao , Guanbin Li

Pathology deals with the practice of discovering the reasons for disease by analyzing the body samples. The most used way in this field, is to use histology which is basically studying and viewing microscopic structures of cell and tissues.…

Image and Video Processing · Electrical Eng. & Systems 2021-11-08 Virender Ranga , Shivam Gupta , Priyansh Agrawal , Jyoti Meena

Weakly supervised instance labeling using only image-level labels, in lieu of expensive fine-grained pixel annotations, is crucial in several applications including medical image analysis. In contrast to conventional instance segmentation…

Computer Vision and Pattern Recognition · Computer Science 2019-07-31 Jayaraman J. Thiagarajan , Satyananda Kashyap , Alexandros Karagyris

Current state-of-the-art methods for object detection rely on annotated bounding boxes of large data sets for training. However, obtaining such annotations is expensive and can require up to hundreds of hours of manual labor. This poses a…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Hannah Kniesel , Leon Sick , Tristan Payer , Tim Bergner , Kavitha Shaga Devan , Clarissa Read , Paul Walther , Timo Ropinski

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

Image and Video Processing · Electrical Eng. & Systems 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li

Localization of chest pathologies in chest X-ray images is a challenging task because of their varying sizes and appearances. We propose a novel weakly supervised method to localize chest pathologies using class aware deep multiscale…

Computer Vision and Pattern Recognition · Computer Science 2018-08-28 Suman Sedai , Dwarikanath Mahapatra , Zongyuan Ge , Rajib Chakravorty , Rahil Garnavi

Weakly supervised nuclei segmentation is a critical problem for pathological image analysis and greatly benefits the community due to the significant reduction of labeling cost. Adopting point annotations, previous methods mostly rely on…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Weizhen Liu , Qian He , Xuming He

Deep-learning-based pipelines have shown the potential to revolutionalize microscopy image diagnostics by providing visual augmentations to a trained pathology expert. However, to match human performance, the methods rely on the…

One of the biggest challenges for applying machine learning to histopathology is weak supervision: whole-slide images have billions of pixels yet often only one global label. The state of the art therefore relies on strongly-supervised…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Olivier Dehaene , Axel Camara , Olivier Moindrot , Axel de Lavergne , Pierre Courtiol

We propose a new method that employs transfer learning techniques to effectively correct sampling selection errors introduced by sparse annotations during supervised learning for automated tumor segmentation. The practicality of current…

Histopathology image analysis is the golden standard of clinical diagnosis for Cancers. In doctors daily routine and computer-aided diagnosis, the Whole Slide Image (WSI) of histopathology tissue is used for analysis. Because of the…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Honglin Li , Yunlong Zhang , Chenglu Zhu , Jiatong Cai , Sunyi Zheng , Lin Yang

Histology images with multi-gigapixel of resolution yield rich information for cancer diagnosis and prognosis. Most of the time, only slide-level label is available because pixel-wise annotation is labour intensive task. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2022-09-08 Made Satria Wibawa , Kwok-Wai Lo , Lawrence Young , Nasir Rajpoot

In histopathological image analysis, feature extraction for classification is a challenging task due to the diversity of histology features suitable for each problem as well as presence of rich geometrical structures. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2016-03-30 Tiep Huu Vu , Hojjat Seyed Mousavi , Vishal Monga , Arvind UK Rao , Ganesh Rao

Annotation-efficient segmentation of the numerous mitochondria instances from various electron microscopy (EM) images is highly valuable for biological and neuroscience research. Although unsupervised domain adaptation (UDA) methods can…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Shan Xiong , Jiabao Chen , Ye Wang , Jialin Peng

The need for labour intensive pixel-wise annotation is a major limitation of many fully supervised learning methods for segmenting bioimages that can contain numerous object instances with thin separations. In this paper, we introduce a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Rihuan Ke , Aurélie Bugeau , Nicolas Papadakis , Peter Schuetz , Carola-Bibiane Schönlieb

The study of histopathological subtypes is valuable for the personalisation of effective treatment strategies for ovarian cancer. However, increasing diagnostic workloads present a challenge for UK pathology departments, leading to the rise…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Marcus Jenkins , Jasenka Mazibrada , Bogdan Leahu , Michal Mackiewicz

Digital pathology has become a standard in the pathology workflow due to its many benefits. These include the level of detail of the whole slide images generated and the potential immediate sharing of cases between hospitals. Recent…

Human-Computer Interaction · Computer Science 2023-07-18 Cristian Camilo Pulgarín-Ospina , Rocío del Amor , Adrián Colomera , Julio Silva-Rodríguez , Valery Naranjo

A key challenge in cancer immunotherapy biomarker research is quantification of pattern changes in microscopic whole slide images of tumor biopsies. Different cell types tend to migrate into various tissue compartments and form variable…

Computer Vision and Pattern Recognition · Computer Science 2018-09-25 Amal Lahiani , Jacob Gildenblat , Irina Klaman , Nassir Navab , Eldad Klaiman