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Definitive cancer diagnosis and management depend upon the extraction of information from microscopy images by pathologists. These images contain complex information requiring time-consuming expert human interpretation that is prone to…

Trained using only image class label, deep weakly supervised methods allow image classification and ROI segmentation for interpretability. Despite their success on natural images, they face several challenges over histology data where ROI…

Image and Video Processing · Electrical Eng. & Systems 2022-05-13 Soufiane Belharbi , Jérôme Rony , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Recent years witnessed remarkable progress in computational histopathology, largely fueled by deep learning. This brought the clinical adoption of deep learning-based tools within reach, promising significant benefits to healthcare,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-29 Ahmad Obeid , Said Boumaraf , Anabia Sohail , Taimur Hassan , Sajid Javed , Jorge Dias , Mohammed Bennamoun , Naoufel Werghi

Annotating cancerous regions in whole-slide images (WSIs) of pathology samples plays a critical role in clinical diagnosis, biomedical research, and machine learning algorithms development. However, generating exhaustive and accurate…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Zhenzhen Wang , Carla Saoud , Sintawat Wangsiricharoen , Aaron W. James , Aleksander S. Popel , Jeremias Sulam

Diagnosing basal cell carcinomas (BCC), one of the most common cutaneous malignancies in humans, is a task regularly performed by pathologists and dermato-pathologists. Improving histological diagnosis by providing diagnosis suggestions,…

Deep learning-based methods are gaining traction in digital pathology, with an increasing number of publications and challenges that aim at easing the work of systematically and exhaustively analyzing tissue slides. These methods often…

Image and Video Processing · Electrical Eng. & Systems 2020-06-25 Ting-An Yen , Hung-Chun Hsu , Pushpak Pati , Maria Gabrani , Antonio Foncubierta-Rodríguez , Pau-Choo Chung

To train a robust deep learning model, one usually needs a balanced set of categories in the training data. The data acquired in a medical domain, however, frequently contains an abundance of healthy patients, versus a small variety of…

Image and Video Processing · Electrical Eng. & Systems 2020-03-09 Jevgenij Gamper , Brandon Chan , Yee Wah Tsang , David Snead , Nasir Rajpoot

In digital pathology, segmenting densely distributed objects like glands and nuclei is crucial for downstream analysis. Since detailed pixel-wise annotations are very time-consuming, we need semi-supervised segmentation methods that can…

Image and Video Processing · Electrical Eng. & Systems 2024-07-18 Meilong Xu , Xiaoling Hu , Saumya Gupta , Shahira Abousamra , Chao Chen

This paper presents a study on few-shot classification in the context of histopathology images. While few-shot learning has been studied for natural image classification, its application to histopathology is relatively unexplored. Given the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Ardhendu Sekhar , Ravi Kant Gupta , Amit Sethi

Pixel-wise segmentation is one of the most data and annotation hungry tasks in our field. Providing representative and accurate annotations is often mission-critical especially for challenging medical applications. In this paper, we propose…

Computer Vision and Pattern Recognition · Computer Science 2021-04-28 Simon Reiß , Constantin Seibold , Alexander Freytag , Erik Rodner , Rainer Stiefelhagen

Histopathology is critical for the diagnosis of many diseases, including cancer. These protocols typically require pathologists to manually evaluate slides under a microscope, which is time-consuming and subjective, leading to interest in…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Kianoush Falahkheirkhah , Alex Lu , David Alvarez-Melis , Grace Huynh

A critical challenge of training deep learning models in the Digital Pathology (DP) domain is the high annotation cost by medical experts. One way to tackle this issue is via transfer learning from the natural image domain (NI), where the…

Image and Video Processing · Electrical Eng. & Systems 2022-01-24 Eu Wern Teh , Graham W. Taylor

Standard segmentation of medical images based on full-supervised convolutional networks demands accurate dense annotations. Such learning framework is built on laborious manual annotation with restrict demands for expertise, leading to…

Computer Vision and Pattern Recognition · Computer Science 2020-10-26 Liyan Sun , Jianxiong Wu , Xinghao Ding , Yue Huang , Guisheng Wang , Yizhou Yu

The clinical diagnosis of skin lesion involves the analysis of dermoscopic and clinical modalities. Dermoscopic images provide a detailed view of the surface structures whereas clinical images offer a complementary macroscopic information.…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Hao Wang , Euijoon Ahn , Lei Bi , Jinman Kim

We present a novel approach to train pixel resolution segmentation models on whole slide images in a weakly supervised setup. The model is trained to classify patches extracted from slides. This leads the training to be made under noisy…

Image and Video Processing · Electrical Eng. & Systems 2019-07-19 Nicolas Pinchaud

Few-shot learning is a standard practice in most deep learning based histopathology image segmentation, given the relatively low number of digitized slides that are generally available. While many models have been developed for domain…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Zheng Yuan , Andre Esteva , Ran Xu

Cell detection and segmentation is fundamental for all downstream analysis of digital pathology images. However, obtaining the pixel-level ground truth for single cell segmentation is extremely labor intensive. To overcome this challenge,…

Computer Vision and Pattern Recognition · Computer Science 2019-10-29 Alireza Chamanzar , Yao Nie

Annotated images and ground truth for the diagnosis of rare and novel diseases are scarce. This is expected to prevail, considering the small number of affected patient population and limited clinical expertise to annotate images. Further,…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Karthik Desingu , Mirunalini P. , Aravindan Chandrabose

Cell detection and segmentation are integral parts of automated systems in digital pathology. Encoder-decoder networks have emerged as a promising solution for these tasks. However, training of these networks has typically required full…

In pathology, the spatial distribution and proportions of tissue types are key indicators of disease progression, and are more readily available than fine-grained annotations. However, these assessments are rarely mapped to pixel-wise…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Yangping Li , Thomas Pinetz , Michael Hölzel , Marieta Toma , Alexander Effland
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