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Spherical multi-layered structures are prevalent in numerous biological systems and engineered applications, including tumor spheroids, layered tissues, and multi-shell nanoparticles for targeted drug delivery. Despite their widespread…

Information Theory · Computer Science 2025-03-19 Mitra Rezaei , Michael Chappell , Adam Noel

Cells are complex structures which require considerable amounts of organization via transport of large intracellular cargo. While passive diffusion is often sufficiently fast for the transport of smaller cargo, active transport is necessary…

Biomolecules · Quantitative Biology 2018-08-29 Robert Blackwell , David Jung , Mona Bukenberger , Ana-Sunčana Smith

Movements of molecular motors on cytoskeletal filaments are described by directed walks on a line. Detachment from this line is allowed to occur with a small probability. Motion in the surrounding fluid is described by symmetric random…

Statistical Mechanics · Physics 2007-05-23 Theo M. Nieuwenhuizen , Stefan Klumpp , Reinhard Lipowsky

A tight binding model for scanning tunneling microscopy images of a molecule adsorbed on a metal surface is described. The model is similar in spirit to that used to analyze conduction along molecular wires connecting two metal leads and…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 Yoel Calev , Hezy Cohen , Gianaurelio Cuniberti , Abraham Nitzan , Danny Porath

Rolling lubrication with spherical molecules working as 'nanobearings' has failed experimentally so far, without a full understanding of the physics involved and of the reasons why. Past model simulations and common sense have shown that…

Soft Condensed Matter · Physics 2008-09-08 Oleg M. Braun , Erio Tosatti

The goal of the present article is to review the major developments that have led to the current understanding of molecule-field interactions and experimental methods for manipulating molecules with electromagnetic fields. Molecule-field…

Atomic Physics · Physics 2013-09-18 Mikhail Lemeshko , Roman V. Krems , John M. Doyle , Sabre Kais

The fabrication of nanomaterials involves self-ordering processes of functional molecules on inorganic surfaces. To obtain specific molecular arrangements, a common strategy is to equip molecules with functional groups. However, focusing on…

Mesoscale and Nanoscale Physics · Physics 2021-04-28 Andreas Jeindl , Jari Domke , Lukas Hörmann , Falko Sojka , Roman Forker , Torsten Fritz , Oliver T. Hofmann

Colloidal membranes, self assembled monolayers of aligned rod like molecules, offer a template for designing membranes with definite shapes and curvature, and possibly new functionalities in the future. Often the constituent rods, due to…

Soft Condensed Matter · Physics 2020-07-31 Sk Ashif Akram , Arabinda Behera , Prerna Sharma , Anirban Sain

The transport of cargo particles which are pulled by several molecular motors in a cooperative manner is studied theoretically. The transport properties depend primarily on the maximal number, $N$, of motor molecules that may pull…

Subcellular Processes · Quantitative Biology 2007-05-23 Stefan Klumpp , Reinhard Lipowsky

The mechanism of Kondo screening in strongly correlated molecules with several unpaired electrons on a metal surface is still under debate. Here, we provide a theoretical framework that rationalizes the emergence of Kondo screening…

Strongly Correlated Electrons · Physics 2024-10-17 Aitor Calvo-Fernández , Manish Kumar , Diego Soler-Polo , Asier Eiguren , María Blanco-Rey , Pavel Jelínek

The motion of molecules across channels is critically important for understanding mechanisms of cellular processes. Here we investigate the mechanism of interactions in the molecular transport by analyzing exactly solvable discrete…

Soft Condensed Matter · Physics 2015-05-18 Anatoly B. Kolomeisky , Karthik Uppulury

Molecules with versatile functionalities and well-defined structures, can serve as building blocks for extreme nanoscale devices. This requires their precise integration into functional heterojunctions, most commonly in the form of…

The study of Molecular Communication(MC) is more and more prevalence, and channel model of MC plays an important role in the MC System. Since different propagation environment and modulation techniques produce different channel model, most…

Emerging Technologies · Computer Science 2016-03-14 Pengfei Lu , Yang You , Bo Liu , Zhenqiang Wu

Particles moving in oscillating potential with broken mirror symmetry are considered. We calculate their energetic efficiency, when acting as molecular motors carrying a load against external force. It is shown that interaction between…

Statistical Mechanics · Physics 2010-09-03 Frantisek Slanina

In living cells, molecular motors convert chemical energy into mechanical work. Its thermodynamic energy efficiency, i.e. the ratio of output mechanical work to input chemical energy, is usually high. However, using two-state models, we…

Biological Physics · Physics 2015-03-06 Yunxin Zhang

Since the first measurement of electron tunneling through an organic monolayer in 1971,(Mann and Kuhn, 1971) and the gedanken experiment of a molecular current rectifying diode in 1974,(Aviram and Ratner, 1974) molecular-scale electronics…

Mesoscale and Nanoscale Physics · Physics 2010-05-17 D. Vuillaume

Cells are strongly out-of-equilibrium systems driven by continuous energy supply. They carry out many vital functions requiring active transport of various ingredients and organelles, some being small, others being large. The cytoskeleton,…

Biological Physics · Physics 2017-09-20 Cecile Appert-Rolland , Maximilian Ebbinghaus , Ludger Santen

In the last years there has been a great interest in magnetic systems formed by a cluster of transition metal ions covalently bonded via superexchange bridges, embedded in a large organic molecule. Following the synthesis and the structural…

Materials Science · Physics 2007-05-23 F. Borsa , A. Lascialfari , Y. Furukawa

Cellular cargo can be bound to cytoskeletal filaments by one or multiple active or passive molecular motors. Recent experiments have shown that the presence of auxiliary, nondriving motors, results in an enhanced processivity of the cargo,…

Biomolecules · Quantitative Biology 2019-03-27 Filippo Posta , Maria R. D'Orsogna , Tom Chou

Molecular representation is a critical element in our understanding of the physical world and the foundation for modern molecular machine learning. Previous molecular machine learning models have employed strings, fingerprints, global…

Machine Learning · Computer Science 2025-05-28 Daniil A. Boiko , Thiago Reschützegger , Benjamin Sanchez-Lengeling , Samuel M. Blau , Gabe Gomes
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