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In cells, cytoskeletal filament networks are responsible for cell movement, growth, and division. Filaments in the cytoskeleton are driven and organized by crosslinking molecular motors. In reconstituted cytoskeletal systems, motor activity…

Dynamics of molecular motors that move along linear lattices and interact with them via reversible destruction of specific lattice bonds is investigated theoretically by analyzing exactly solvable discrete-state ``burnt-bridge'' models.…

Soft Condensed Matter · Physics 2009-11-13 Max N. Artyomov , Alexander Yu. Morozov , Anatoly B. Kolomeisky

The friction and adhesion between elastic bodies are strongly influenced by the roughness of the surfaces in contact. Here we develop a multiscale molecular dynamics approach to contact mechanics, which can be used also when the surfaces…

Soft Condensed Matter · Physics 2007-05-23 C. Yang , U. Tartaglino , B. N. J. Persson

Cell is the structural and functional unit of life. This Resource Letter serves as a guide to the literature on nano-machines which drive not only intracellular movements, but also motility of the cell. These machines are usually proteins…

Biological Physics · Physics 2008-07-18 Debashish Chowdhury

Within living cells, the transport of cargo is accomplished by groups of molecular motors. Such collective transport could utilize mechanisms which emerge from inter-motor interactions in ways that are yet to be fully understood. Here we…

Biomolecules · Quantitative Biology 2016-10-04 David Ando , Michelle K. Mattson , Jing Xu , Ajay Gopinathan

We study the motion of dispersed nanoprobes in entangled active-passive polymer mixtures. By comparing the two architectures of linear vs. unconcatenated and unknotted circular polymers, we demonstrate that novel, rich physics emerge. For…

Soft Condensed Matter · Physics 2021-08-27 Andrea Papale , Jan Smrek , Angelo Rosa

The distances over which biological molecules and their complexes can function range from a few nanometres, in the case of folded structures, to millimetres, for example during chromosome organization. Describing phenomena that cover such…

Soft Condensed Matter · Physics 2011-09-28 Changbong Hyeon , D. Thirumalai

This paper presents a proposal of a rather new type of effective interatomic interaction for molecular dynamics and similar applications. The model consists of atoms with prescribed geometric arrangement of active orbitals, represented by…

Chemical Physics · Physics 2009-10-19 Ladislav Kocbach , Suhail Lubbad

Soft particles such as microgels and core-shell particles can undergo significant and anisotropic deformations when adsorbed to a liquid interface. This, in turn, leads to a complex phase behavior upon compression. Here we develop a…

The molecular machinery of life is largely created via self-organisation of individual molecules into functional assemblies. Minimal coarse-grained models, where a whole macromolecule is represented by a small number of particles, can be of…

Biological Physics · Physics 2019-06-25 Anne E. Hafner , Johannes Krausser , Anđela Šarić

The transport by molecular motors along cytoskeletal filaments is studied theoretically in the presence of static defects. The movements of single motors are described as biased random walks along the filament as well as binding to and…

Biological Physics · Physics 2009-05-08 Yan Chai , Reinhard Lipowsky , Stefan Klumpp

Artificial Intelligence (AI) and Machine Learning (ML) are weaving their way into the fabric of society, where they are playing a crucial role in numerous facets of our lives. As we witness the increased deployment of AI and ML in various…

Emerging Technologies · Computer Science 2022-12-23 Sasitharan Balasubramaniam , Samitha Somathilaka , Sehee Sun , Adrian Ratwatte , Massimiliano Pierobon

A network of semiflexible biopolymers, known as the cytoskeleton, and molecular motors play fundamental mechanical roles in cellular activities. The cytoskeletal response to forces generated by molecular motors is profoundly linked to…

Soft Condensed Matter · Physics 2022-05-25 N. Honda , K. Shiraki , F. van Esterik , S. Inokuchi , H. Ebata , D. Mizuno

Transport of molecular motors along protein filaments in a half-closed geometry is a common feature of biologically relevant processes in cellular protrusions. Using a lattice gas model we study how the interplay between active and…

Biological Physics · Physics 2017-03-30 Isabella R. Graf , Erwin Frey

We present the state-of-the-art theoretical modeling, molecular simulation, and coarse-graining strategies for the transport of gases and liquids in nanoporous materials (pore size 1-100 nm). Special emphasis is placed on the transport of…

Soft Condensed Matter · Physics 2025-01-29 Alexander Schlaich , Jean-Louis Barrat , Benoit Coasne

In recent years, progresses in nanotechnology have established the foundations for implementing nanomachines capable of carrying out simple but significant tasks. Under this stimulus, researchers have been proposing various solutions for…

Emerging Technologies · Computer Science 2018-08-14 Luca Felicetti , Mauro Femminella , Gianluca Reali , Pietro Liò

This article examines recent research in molecular communications from a telecommunications system design perspective. In particular, it focuses on channel models and state-of-the-art physical layer techniques. The goal is to provide a…

Emerging Technologies · Computer Science 2015-07-28 Weisi Guo , Taufiq Asyhari , Nariman Farsad , H. Birkan Yilmaz , Bin Li , Andrew Eckford , Chan-Byoung Chae

Surfaces are at the frontier of every known solid. They provide versatile supports for functional nanostructures and mediate essential physicochemical processes. Being intimately related with 2D materials, interfaces and atomically thin…

In a single molecule assay, the motion of a molecular motor is often inferred from measuring the stochastic trajectory of a large probe particle attached to it. We discuss a simple model for this generic set-up taking into account…

Statistical Mechanics · Physics 2012-11-22 Eva Zimmermann , Udo Seifert

In macroscopic mechanical devices torque is transmitted through gearwheels and clutches. In the construction of devices at the nanoscale, torque and its transmission through soft materials will be a key component. However, this regime is…

Soft Condensed Matter · Physics 2018-06-12 Ian Williams , Erdal C. Oğuz , Thomas Speck , Paul Bartlett , Hartmut Löwen , C. Patrick Royall