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Segmentation is an important analysis task for biomedical images, enabling the study of individual organelles, cells or organs. Deep learning has massively improved segmentation methods, but challenges remain in generalization to new…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Carolin Teuber , Anwai Archit , Constantin Pape

Cryo-electron tomography (cryo-ET) is uniquely suited to precisely localize macromolecular complexes in situ, that is in a close-to-native state within their cellular compartments, in three-dimensions at high resolution. Point pattern…

Quantitative Methods · Quantitative Biology 2022-03-02 Antonio Martinez-Sanchez , Wolfgang Baumeister , Vladan Lučić

There is a clear need for developments in characterisation techniques that provide detailed information about structure-function relationships in biology. Using electron microscopy to achieve high resolution while maintaining a broad field…

Quantitative Methods · Quantitative Biology 2023-09-12 Chen Huang , Judy S. Kim , Angus I. Kirkland

Particle-in-cell merging algorithms aim to resample dynamically the six-dimensional phase space occupied by particles without distorting substantially the physical description of the system. Whereas various approaches have been proposed in…

Plasma Physics · Physics 2015-11-16 Marija Vranic , Thomas Grismayer , Joana L. Martins , Ricardo A. Fonseca , Luis O. Silva

Liquid Argon Time Projection Chambers (LArTPCs) are high resolution particle imaging detectors, employed by accelerator-based neutrino oscillation experiments for high precision physics measurements. While images of particle trajectories…

Instrumentation and Detectors · Physics 2020-07-08 Dae Heun Koh , Pierre Côte de Soux , Laura Dominé , François Drielsma , Ran Itay , Qing Lin , Kazuhiro Terao , Ka Vang Tsang , Tracy Usher

Single particle cryogenic electron microscopy (cryo-EM) is an imaging technique capable of recovering the high-resolution 3-D structure of biological macromolecules from many noisy and randomly oriented projection images. One notable…

Biomolecules · Quantitative Biology 2024-01-30 Andy Zhang , Oscar Mickelin , Joe Kileel , Eric J. Verbeke , Nicholas F. Marshall , Marc Aurèle Gilles , Amit Singer

Particle filters are not compatible with automatic differentiation due to the presence of discrete resampling steps. While known estimators for the score function, based on Fisher's identity, can be computed using particle filters, up to…

Machine Learning · Statistics 2021-10-20 Adam Ścibior , Frank Wood

Scanning electron microscopy (SEM), a century-old technique, is today a ubiquitous method of imaging the surface of nanostructures. However, most SEM detectors simply count the number of secondary electrons from a material of interest, and…

This paper extends the concept of Laplacian filtered quasi-Helmholtz decompositions we have recently introduced, to the basis-free projector-based setting. This extension allows the discrete analyses of electromagnetic integral operators…

Image and Video Processing · Electrical Eng. & Systems 2022-03-17 Adrien Merlini , Clément Henry , Davide Consoli , Lyes Rahmouni , Francesco P. Andriulli

In this paper, we propose an approach to the unsupervised segmentation of images using Markov Random Field. The proposed approach is based on the idea of Bit Plane Slicing. We use the planes as initial labellings for an ensemble of…

Computer Vision and Pattern Recognition · Computer Science 2014-10-29 Balint Antal , Bence Remenyik , Andras Hajdu

We introduce neural particle smoothing, a sequential Monte Carlo method for sampling annotations of an input string from a given probability model. In contrast to conventional particle filtering algorithms, we train a proposal distribution…

Computation and Language · Computer Science 2018-05-01 Chu-Cheng Lin , Jason Eisner

Cryo-electron microscopy provides 2-D projection images of the 3-D electron scattering intensity of many instances of the particle under study (e.g., a virus). Both symmetry (rotational point groups) and heterogeneity are important aspects…

Applications · Statistics 2019-05-17 Nan Xu , Peter C Doerschuk

Electron and scanning probe microscopy produce vast amounts of data in the form of images or hyperspectral data, such as EELS or 4D STEM, that contain information on a wide range of structural, physical, and chemical properties of…

Machine Learning · Computer Science 2023-06-09 Arpan Biswas , Maxim Ziatdinov , Sergei V. Kalinin

This work provides a new multinomial resampling procedure for particle filter resampling, focused on the case where the number of samples required is less than or equal to the size of the underlying discrete distribution. This setting is…

Data Structures and Algorithms · Computer Science 2026-04-03 Andrey A. Popov

In recent work (arXiv:1006.3100v1), we have presented a novel approach for improving particle filters for multi-target tracking. The suggested approach was based on drift homotopy for stochastic differential equations. Drift homotopy was…

Numerical Analysis · Mathematics 2011-02-11 Vasileios Maroulas , Panagiotis Stinis

Automatic detection of lymphocyte in H&E images is a necessary first step in lots of tissue image analysis algorithms. An accurate and robust automated lymphocyte detection approach is of great importance in both computer science and…

Computer Vision and Pattern Recognition · Computer Science 2016-12-13 Jianxu Chen , Chukka Srinivas

Cryogenic electron microscopy (cryo-EM) is an invaluable technique for determining high-resolution three-dimensional structures of biological macromolecules using transmission particle images. The inherent symmetry in these macromolecules…

Optimization and Control · Mathematics 2024-11-06 Qi Zhang , Chenglong Bao , Hai Lin , Mingxu Hu

Sequential Monte Carlo methods have been a major breakthrough in the field of numerical signal processing for stochastic dynamical state-space systems with partial and noisy observations. However, these methods still present certain…

Applications · Statistics 2023-12-14 Samuel Nyobe , Fabien Campillo , Serge Moto , Vivien Rossi

Scanning transmission electron microscopy is a common tool used to study the atomic structure of materials. It is an inherently multimodal tool allowing for the simultaneous acquisition of multiple information channels. Despite its…

Recent advances in the synthesis of polar molecular materials have produced practical alternatives to ferroelectric ceramics, opening up exciting new avenues for their incorporation into modern electronic devices. However, in order to…

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