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Functional connectivity is a key approach to investigate oscillatory activities of the brain that provides important insights on the underlying dynamic of neuronal interactions and that is mostly applied for brain activity analysis.…

Neurons and Cognition · Quantitative Biology 2022-02-17 Marie-Constance Corsi , Sylvain Chevallier , Fabrizio De Vico Fallani , Florian Yger

It has become increasingly popular to study the brain as a network due to the realization that functionality cannot be explained exclusively by independent activation of specialized regions. Instead, across a large spectrum of behaviors,…

Neurons and Cognition · Quantitative Biology 2014-07-22 Petko Bogdanov , Nazli Dereli , Danielle S. Bassett , Scott T. Grafton , Ambuj K. Singh

Functional brain network has been widely studied to understand the relationship between brain organization and behavior. In this paper, we aim to explore the functional connectivity of brain network under a \emph{multi-step} cognitive task…

Neurons and Cognition · Quantitative Biology 2017-12-06 Shi-Min Cai , Wei Chen , Dong-Bai Liu , Ming Tang , Xun Chen

Dynamic functional connectivity (DFC) analysis involves measuring correlated neural activity over time across multiple brain regions. Significant regional correlations among neural signals, such as those obtained from resting-state…

The extraction of brain functioning features is a crucial step in the definition of brain-computer interfaces (BCIs). In the last decade, functional connectivity (FC) estimators have been increasingly explored based on their ability to…

Neurons and Cognition · Quantitative Biology 2019-12-06 Tiziana Cattai , Stefania Colonnese , Marie-Constance Corsi , Danielle S. Bassett , Gaetano Scarano , Fabrizio De Vico Fallani

Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…

Most generally, dynamic functional connectivity (FC) refers to the non-instantaneous couplings across timeseries from a set of brain areas, here as measured by fMRI. This is in contrast to static FC, which is defined as purely instantaneous…

Neurons and Cognition · Quantitative Biology 2023-01-10 Christine Ahrends , Diego Vidaurre

Objective: New measures of human brain connectivity are needed to address gaps in the existing measures and facilitate the study of brain function, cognitive capacity, and identify early markers of human disease. Traditional approaches to…

Neurons and Cognition · Quantitative Biology 2023-08-28 Cooper J. Mellema , Albert Montillo

The idea to estimate the statistical interdependence among (interacting) brain regions has motivated numerous researchers to investigate how the resulting connectivity patterns and networks may organize themselves under any conceivable…

Neurons and Cognition · Quantitative Biology 2021-02-03 Matteo Fraschini , Simone Maurizio La Cava , Luca Didaci , Luigi Barberini

Functional magnetic resonance imaging (fMRI) data have become increasingly available and are useful for describing functional connectivity (FC), the relatedness of neuronal activity in regions of the brain. This FC of the brain provides…

Machine Learning · Statistics 2020-10-14 Andrew DiLernia , Karina Quevedo , Jazmin Camchong , Kelvin Lim , Wei Pan , Lin Zhang

Brain function emerges from coordinated activity across anatomically connected regions, where structural connectivity (SC) -- the network of white matter pathways - provides the physical substrate for functional connectivity (FC) -- the…

Neurons and Cognition · Quantitative Biology 2025-07-09 Sam Frank Kelemen , Joaquín Gõni , Sérgio Pequito , Arian Ashourvan

Functional brain network (FBN) modeling often relies on local pairwise interactions, whose limitation in capturing high-order dependencies is theoretically analyzed in this paper. Meanwhile, the computational burden and heuristic nature of…

Machine Learning · Computer Science 2025-10-13 Ling Zhan , Junjie Huang , Xiaoyao Yu , Wenyu Chen , Tao Jia

In recent years, there has been strong interest in neuroscience studies to investigate brain organization through networks of brain regions that demonstrate strong functional connectivity (FC). These networks are extracted from observed…

Applications · Statistics 2017-03-14 Phebe Brenne Kemmer , F. DuBois Bowman , Helen Mayberg , Ying Guo

Mapping the brain imaging data to networks, where each node represents a specific area of the brain, has enabled an objective graph-theoretic analysis of human connectome. However, the latent structure on higher-order connections remains…

Neurons and Cognition · Quantitative Biology 2019-04-09 Bosiljka Tadic , Miroslav Andjelkovic , Roderick Melnik

Connectivity studies using resting-state functional magnetic resonance imaging are increasingly pooling data acquired at multiple sites. While this may allow investigators to speed up recruitment or increase sample size, multisite studies…

Quantitative Methods · Quantitative Biology 2017-02-10 Christian Dansereau , Yassine Benhajali , Celine Risterucci , Emilio Merlo Pich , Pierre Orban , Douglas Arnold , Pierre Bellec

We investigate scaling properties of human brain functional networks in the resting-state. Analyzing network degree distributions, we statistically test whether their tails scale as power-law or not. Initial studies, based on least-squares…

Neurons and Cognition · Quantitative Biology 2017-02-03 Riccardo Zucca , Xerxes D. Arsiwalla , Hoang Le , Mikail Rubinov , Paul Verschure

The study of dynamic functional connectomes has provided valuable insights into how patterns of brain activity change over time. Neural networks process information through artificial neurons, conceptually inspired by patterns of activation…

Neurons and Cognition · Quantitative Biology 2025-08-12 Yutong Wu , Peilin He , Tananun Songdechakraiwut

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

To understand the biological characteristics of neurological disorders with functional connectivity (FC), recent studies have widely utilized deep learning-based models to identify the disease and conducted post-hoc analyses via explainable…

Machine Learning · Computer Science 2023-10-09 Eunsong Kang , Da-woon Heo , Jiwon Lee , Heung-Il Suk

In his book 'A Beautiful Question', physicist Frank Wilczek argues that symmetry is 'nature's deep design,' governing the behavior of the universe, from the smallest particles to the largest structures. While symmetry is a cornerstone of…

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