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The limited data availability and the low signal-to-noise ratio of fMRI signals lead to the challenging task of fMRI-to-image retrieval. State-of-the-art MindEye remarkably improves fMRI-to-image retrieval performance by leveraging a large…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Zixuan Gong , Qi Zhang , Guangyin Bao , Lei Zhu , Ke Liu , Liang Hu , Duoqian Miao , Yu Zhang

Recent advances in neuroimaging have deepened our understanding of the brain's complex functional and structural organization. Among these, functional Magnetic Resonance Imaging (fMRI) - particularly resting-state fMRI (rs-fMRI) - has…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 M. Moein Esfahani , Sepehr Salem Ghahfarokhi , Mohammed Alser , Jingyu Liu , Vince Calhoun

Two-photon microscopy is a powerful tool for in vivo imaging, but its imaging depth is typically limited to a few hundred microns due to tissue scattering, even with existing scattering correction techniques. Moreover, most active…

Optics · Physics 2025-05-29 Renzhi He , Yucheng Li , Brianna Urbina , Jiandi Wan , Yi Xue

We have designed and characterized a micro-SQUID with dispersive readout for use in low temperature scanning probe microscopy systems. The design features a capacitively shunted RF SQUID with a tunable resonance frequency from 5 to 12 GHz,…

The CamCAN Lifespan Neuroimaging Dataset, Cambridge (UK) Centre for Ageing and Neuroscience, was acquired and processed beginning in December, 2016. The referee consensus solver deployed to the Open Science Grid was used for this task. The…

Neurons and Cognition · Quantitative Biology 2017-12-11 Don Krieger , Paul Shepard , Ben Zusman , Anirban Jana , David O. Okonkwo

Background: X-nuclei imaging (e.g. 31P MRI) suffers low SNR due to lower gyromagnetic ratios and tissue concentrations than 1H MRI. Enhancing SNR requires high fields, advanced coils, optimized sequences, and sophisticated reconstruction…

Medical Physics · Physics 2024-10-08 Pontus Pandurevic , Mark Stephan Widmaier , Zhiwei Huang , Lijing Xin

Currently, state-of-the-art motor intention decoding algorithms in brain-machine interfaces are mostly implemented on a PC and consume significant amount of power. A machine learning co-processor in 0.35um CMOS for motor intention decoding…

Machine Learning · Computer Science 2016-11-15 Yi Chen , Enyi Yao , Arindam Basu

The TT-PET collaboration is developing a small animal TOF-PET scanner based on silicon detectors featuring 30 ps RMS time resolution and intended to be inserted in an existing MRI scanner. The TT-PET scanner makes use of a stack of layers…

Magnetoencephalography (MEG) enables the study of brain activity by recording the magnetic fields generated by neural currents and has become an important technique for neuroscientists in research and clinical settings. Unlike the…

Accurate modeling of electric potential and current distribution in head tissues is crucial for the design and evaluation of neuro-sensing and neuro-stimulation systems operating in the sub megahertz frequency range. Numerical methods are…

Computational Engineering, Finance, and Science · Computer Science 2026-05-29 Angelo Faccia , Ermanno Citraro , Francesco P. Andriulli

Quantum diamond magnetometers using lock-in detection have successfully detected weak bio-magnetic fields from neurons, a live mammalian muscle, and a live mouse heart. This opens up the possibility of quantum diamond magnetometers…

Quantum Physics · Physics 2023-07-04 Sangwon Oh , Seong-Joo Lee , Jeong Hyun Shim , Nam Woong Song , Truong Thi Hien

The combination of surface coils and metamaterials remarkably enhance magnetic resonance imaging (MRI) performance for significant local staging flexibility. However, due to the coupling in between, impeded signal-to-noise ratio (SNR) and…

Medical Physics · Physics 2023-11-01 Qun Ren , Yuxin Lang , Yuqi Ja , Xia Xiao , Yu Liu , Xiangzheng Kong , Ruiqi Jin , Yongqing He , Jianwei You , Wei Sha , Yanwei Pang

Photoacoustic Microscopy (PAM) images integrating the advantages of optical contrast and acoustic resolution have been widely used in brain studies. However, there exists a trade-off between scanning speed and image resolution. Compared…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Kai Pan , Linyang Li , Li Lin , Pujin Cheng , Junyan Lyu , Lei Xi , Xiaoyin Tang

Automated sample preparation and electron microscopy enables acquisition of very large image data sets. These technical advances are of special importance to the field of neuroanatomy, as 3D reconstructions of neuronal processes at the nm…

We report on the design and performance of a cryogenic (300 mK) near-field scanning microwave microscope. It uses a microwave resonator as the near-field sensor, operating at a frequency of 6 GHz and microwave probing amplitudes down to 100…

Mesoscale and Nanoscale Physics · Physics 2014-04-03 S. E. de Graaf , A. V. Danilov , A. Adamyan , S. E. Kubatkin

Purpose: This study aims to develop a high-resolution whole-brain multi-parametric quantitative MRI approach for simultaneous mapping of myelin-water fraction (MWF), T1, T2, and proton-density (PD), all within a clinically feasible scan…

Real-time magnetic resonance imaging (MRI) poses unique challenges related to the speed of data acquisition and to the degree of undersampling necessary to achieve this speed. This Master's thesis introduces and evaluates two pre-processing…

Medical Physics · Physics 2019-06-13 H. Christian M. Holme

The design and experimental demonstration of a large-area, ultra-high-Q-factor and single-mode operation silicon ring resonator based on a strip silicon photonic waveguide are presented, which is suitable for photon gyroscopic application.…

Optics · Physics 2021-11-24 Bai Mou , Yan Boxia , Qi Yan , Wang Yanwei , Han Zhe , Yuanyuan Fan , WangYu

Purpose: To develop an accelerated Cartesian MRF implementation using a multi-shot EPI sequence for rapid simultaneous quantification of T1 and T2 parameters. Methods: The proposed Cartesian MRF method involved the acquisition of highly…

Super-resolution ultrasound imaging (SRUS) is an active area of research as it brings up to a ten-fold improvement in the resolution of microvascular structures. The limitations to the clinical adoption of SRUS include long acquisition…

Image and Video Processing · Electrical Eng. & Systems 2024-08-05 Arthur David Redfern , Katherine G. Brown